IP Library Granted Patent US 12,060,548
Granted Patent B2
US 12,060,548 · App. 16/962,331 · Granted Aug 13, 2024

Fluid handling apparatus

Inventors: Espir Kahatt (Carlsbad, CA); Chris Harder (Dunrobin, CA); Louwrens Stassen (Kanata, CA); Marie Ashman (Ottawa, CA); Peter Goodings (Ottawa, CA); Saakshi Sutarwala (Ottawa, CA)
Assignee: Genomadix Inc.
C12M23/38C12M23/40C12M37/02C12M37/04G01N1/4077G01N2001/4088
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Quick Facts
Patent No.
US 12,060,548
App. No.
16/962,331
Granted
Aug 13, 2024
Kind
B2
Abstract

A fluid handling apparatus having a two-sided channel plate with channel ports extending from one side to the other. Fluid channels on both sides of the channel plate connected to the channel ports direct fluid through the channel plate in a desired fluid path, and the first face and the second face of the channel plate are sealed to fluidly encase the fluid channels.

Claims (52)

1. A fluid handling apparatus comprising:

a channel plate having a first face and a second face, the channel plate comprising:

a plurality of channel ports extending from the first face to the second face for directing fluid between the first face and the second face of the channel plate;

a plurality of fluid channels, the fluid channels on the first face and the second face of the channel plate, each fluid channel fluidly connected to at least one channel port, wherein each of the fluid channels connects to a channel port of the plurality of channel ports extending from the first face to the second face;

a sample port for receiving fluid to be handled, the sample port fluidly connected to at least one of the plurality of fluid channels; and

an exit port for extracting fluid from the fluid handling apparatus,

wherein the first face and the second face of the channel plate are sealed to fluidly encase the fluid channels; and

a valve plate movable relative to the channel plate, the valve plate comprising at least one channel valve to fluidly connect at least two of the plurality of channel ports and fluid channels, wherein the valve plate is a rotary valve comprising:

a top surface comprising a knob to control rotation of the rotary valve about a central axis; and

a bottom surface comprising the at least one channel valve; and

wherein the channel plate comprises an annular housing to support the rotary valve, and the rotary valve and housing comprises complimentary alignment pins and rotation guides to angularly align the rotary valve relative to the plurality of channel ports.

2. The apparatus of claim 1 , wherein the first face and the second face of the channel plate are sealed with a sealing film.

3. The apparatus of claim 1 , wherein the channel plate has a top side and a bottom side, and wherein the channel plate comprises fluid channels on both the top side and the bottom side.

4. The apparatus of claim 1 , further comprising a hydrophobic vent in at least one of the plurality of fluid channels.

5. The apparatus of claim 1 , wherein the plurality of channel ports are arranged annularly around an axis.

6. The apparatus of claim 1 , wherein the channel plate is fluidly connected to a waste reservoir.

7. The apparatus of claim 1 , wherein the channel plate further comprises a wash aperture.

8. The apparatus of claim 1 , further comprising a base.

9. The apparatus of claim 1 , further comprising a filter fluidly connected to at least one of the plurality of fluid channels.

10. The apparatus of claim 1 , wherein the valve plate is compressible against the channel plate.

11. The apparatus of claim 10 , wherein the valve plate comprises at least one of elastomer and an elastomer gasket.

12. The apparatus of claim 1 , further comprising a compression plate to compress the channel valve of the valve plate against the channel plate.

13. The apparatus of claim 1 , wherein the valve plate comprises a plurality of channel valves.

14. The apparatus of claim 12 , wherein the compression plate and rotary valve comprise complimentary divets and compression bumps to bias the rotary valve against the channel plate.

15. The apparatus of claim 8 , further comprising a cover.

16. The apparatus of claim 15 , wherein the cover is movable relative to the base.

17. The apparatus of claim 15 , wherein the cover is rotatable relative to the base.

18. The apparatus of claim 1 , wherein the channel plate is supported by a sidewall.

19. A fluid handling apparatus comprising:

a channel plate having a first face and a second face, the channel plate comprising :

a plurality of channel ports extending from the first face to the second face for directing fluid between the first face and the second face of the channel plate; a plurality of fluid channels, the fluid channels on the first face and the second face of the channel plate, each fluid channel fluidly connected to at least one channel port, wherein each of the fluid channels connects the channel ports extending from the first face to the second face;

a sample port for receiving fluid to be handled, the sample port fluidly connected to at least one of the plurality of fluid channels; and

an exit port for extracting fluid from the fluid handling apparatus, wherein the first face and the second face of the channel plate are sealed to fluidly encase the fluid channels;

a valve plate movable relative to the channel plate, the valve plate comprising at least one channel valve to fluidly connect at least two of the plurality of channel ports and fluid channels, wherein the valve plate is a rotary valve comprising:

a top surface comprising a knob to control rotation of the rotary valve about a central axis; and

a bottom surface comprising the at least one channel valve; and

a compression plate to compress the channel valve of the valve plate against the channel plate wherein the compression plate and rotary valve comprise complimentary divets and compression bumps to bias the rotary valve against the channel plate.

20. The apparatus of claim 19 , wherein the first face and the second face of the channel plate are sealed with a sealing film.

21. The apparatus of claim 19 , wherein the channel plate has a top side and a bottom side, and wherein the channel plate comprises fluid channels on both the top side and the bottom side.

22. The apparatus of claim 19 , further comprising a hydrophobic vent in at least one of the plurality of fluid channels.

23. The apparatus of claim 19 , wherein the plurality of channel ports are arranged annularly around an axis.

24. The apparatus of claim 19 , wherein the channel plate is fluidly connected to a waste reservoir.

25. The apparatus of claim 19 , wherein the channel plate further comprises a wash aperture.

26. The apparatus of claim 19 , further comprising a base.

27. The apparatus of claim 19 , further comprising a filter fluidly connected to at least one of the plurality of fluid channels.

28. The apparatus of claim 19 , wherein the valve plate is compressible against the channel plate.

29. The apparatus of claim 28 , wherein the valve plate comprises at least one of elastomer and an elastomer gasket.

30. The apparatus of claim 19 , wherein the valve plate comprises a plurality of channel valves.

31. The apparatus of claim 26 , further comprising a cover.

32. The apparatus of claim 31 , wherein the cover is movable relative to the base.

33. The apparatus of claim 31 , wherein the cover is rotatable relative to the base.

34. The apparatus of claim 19 , wherein the channel plate is supported by a sidewall.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 18, 2023
From: SPARTAN BIOSCIENCE INC.
To: 2856031 ONTARIO INC.
Reel/Frame 065261/0674 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2022
From: SPARTAN BIOSCIENCE, LTD.
To: 2856031 ONTARIO INC.
Reel/Frame 061108/0300 →
CHANGE OF NAME Recorded Sep 15, 2022
From: 2856031 ONTARIO INC.
To: GENOMADIX INC.
Reel/Frame 061448/0242 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 27, 2020
From: KAHATT, ESPIR; HARDER, CHRIS; STASSEN, LOUWRENS; ASHMAN, MARIE; SUTARWALA, SAAKSHI
To: SPARTAN BIOSCIENCE INC.
Reel/Frame 054174/0443 →
Continuity (2)
Provisional Application 62619661 · Jan 19, 2018
Related Publication 20200339928A1 · Oct 29, 2020