Ocular implant and delivery system
An ocular implant including a drug releasing element and having an inlet portion and a Schlemm's canal portion distal to the inlet portion, the inlet portion being disposed at a proximal end of the implant and sized and configured to be placed within an anterior chamber of a human eye, the Schlemm's canal portion being arranged and configured to be disposed within Schlemm's canal of the eye when the inlet portion is disposed in the anterior chamber.
1. An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye, the implant comprising:
a tubular body having an inner surface and an outer surface and comprising a plurality of struts extending along a longitudinal axis of the tubular body and a plurality of open areas surrounded by the plurality of struts, the tubular body extending in a curved volume whose longitudinal axis forms an arc of a circle;
a polymer rod disposed within the curved volume of the tubular body;
at least one therapeutic agent disposed within an interstitial space of the polymer rod; and
the tubular body having a diameter of between 0.005 inches and 0.04 inches.
2. The implant of claim 1 , further comprising a sleeve disposed over an outer surface of the tubular body and the polymer rod.
3. The implant of claim 2 , wherein the sleeve is porous.
4. The implant of claim 1 , wherein the therapeutic agent is an intraocular pressure reducing drug.
5. The implant of claim 1 , wherein when implanted the therapeutic agent is configured to elute from the polymer rod over a period of 1 to 15 years.
6. The implant of claim 1 , further comprising a heparin related coating disposed over an outer surface of the tubular body and the polymer rod.
7. The implant of claim 3 , wherein an elution rate of the therapeutic agent, when implanted, is controlled by a size of one or more pores in the sleeve.