IP Library Granted Patent US 11,506,613
Granted Patent B2
US 11,506,613 · App. 16/968,484 · Granted Nov 22, 2022

Fluid analysis apparatus and method of controlling the same

Inventors: Hong-Geun Kim (Suwon-si, KR); Hyun-Suk Kang (Suwon-si, KR); Jong Gun Lee (Yongin-si, KR); Jong Cheol Kim (Seoul, KR); Seung Woo Han (Busan, KR)
Assignee: PRECISION BIOSENSOR INC.
G01N21/77G01N21/85G01N21/27G01N33/487
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Quick Facts
Patent No.
US 11,506,613
App. No.
16/968,484
Granted
Nov 22, 2022
Kind
B2
Abstract

Provided is a fluid analysis apparatus and a method of controlling the same. The fluid analysis apparatus include an actuator provided on a part of the fluid analysis apparatus, a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated, a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, and a controller configured to control an operation of the actuator based on the optical signal detected by the measurement portion such that the light transmitted from the measurement portion passes through a central portion of the well to perform an accurate inspection on the fluid sample.

Claims (33)

1. A fluid analysis apparatus comprising:

an actuator provided on a part of the fluid analysis apparatus;

a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated;

a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, the measurement portion comprising:

a light source configured to transmit light to the well of the fluid accommodating cartridge; and

a light detector configured to detect optical signals from the transmitted light; and

a controller comprising at least one processor, the controller being configured to control an operation of the actuator to move at least a portion of the measurement portion or the mounting portion based on a width of a strength value of the optical signal detected by the measurement portion, to cause the light transmitted from the measurement portion to pass through a central portion of the well to perform an accurate inspection on the fluid sample,

wherein the width corresponds to a length of time in which the strength value is detected by the measurement portion.

2. The fluid analysis apparatus of claim 1 , wherein the controller is further configured to control the operation of the actuator to align the measurement portion with the well to cause the light transmitted from the measurement portion to pass through the central portion of the well.

3. The fluid analysis apparatus of claim 2 ,

wherein the controller is further configured to control the operation of the actuator to move at least the portion of the measurement portion or the mounting portion to cause a center of the light source, a center of the light detector, and a center of the well to be vertically in line with each other within an error range of a predetermined diameter.

4. The fluid analysis apparatus of claim 1 , wherein the actuator is provided on the mounting portion or the measurement portion, and

the controller is further configured to control the operation of the actuator to move at least the portion of the mounting portion or the measurement portion to cause the light transmitted from the measurement portion to pass through the central portion of the well.

5. The fluid analysis apparatus of claim 4 , wherein the controller is further configured to control the operation of the actuator to move a pin hole portion included in the measurement portion.

6. The fluid analysis apparatus of claim 1 , wherein the controller is further configured to:

identify that the fluid accommodating cartridge is abnormally mounted based on the width of the strength value of the optical signal being outside of an allowable range, and

control the operation of the actuator to cause the width of the strength value of the optical signal to be within the allowable range.

7. The fluid analysis apparatus of claim 6 , wherein the controller is further configured to:

upon identifying that the fluid accommodating cartridge is abnormally mounted, identify a mis-installation direction of the fluid accommodating cartridge based on a change in the width of the strength value while controlling the operation of the actuator, and

control, based on the mis-installation direction that is identified, the operation of the actuator to cause the width of the strength value of the optical signal to be within the allowable range.

8. The fluid analysis apparatus of claim 1 , wherein the measurement portion is further configured to transmit the light to at least one of the well or a groove provided in the fluid accommodating cartridge, and detect the optical signal from the light passed through the at least one of the well or the groove.

9. The fluid analysis apparatus of claim 1 , wherein the fluid analysis apparatus further comprises a plurality of actuators, including the actuator, that are mounted on the mounting portion, and the controller is further configured to control the plurality of actuators to move the mounting portion in an upward direction, a downward direction, a clockwise direction, or a counter-clockwise direction.

10. A fluid analysis apparatus comprising:

an actuator provided on a part of the fluid analysis apparatus;

a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated;

a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, the measurement portion comprising:

a light source configured to transmit light to the well of the fluid accommodating cartridge; and

a light detector configured to detect optical signals from the transmitted light; and

a controller comprising at least one processor, the controller being configured to control an operation of the actuator to move at least a portion of the measurement portion or the mounting portion based on a strength of the optical signal detected by the measurement portion, to cause the light transmitted from the measurement portion to pass through a central portion of the well to perform an accurate inspection on the fluid sample,

wherein the controller is further configured to:

identify that the fluid accommodating cartridge is abnormally mounted based on the strength of the optical signal being outside of an allowable range,

upon identifying that the fluid accommodating cartridge is abnormally mounted, identify a mis-installation direction of the fluid accommodating cartridge based on a change in the strength of the optical signal while controlling the operation of the actuator, and

control, based on the mis-installation direction that is identified, the operation of the actuator to cause the strength of the optical signal to be within the allowable range.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 12, 2022
From: SAMSUNG ELECTRONICS CO., LTD.
To: PRECISION BIOSENSOR INC.
Reel/Frame 060632/0598 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2020
From: KIM, HONG-GEUN; KANG, HYUN-SUK; LEE, JONG GUN; KIM, JONG CHEOL; HAN, SEUNG WOO
To: SAMSUNG ELECTRONICS CO., LTD.
Reel/Frame 053437/0589 →
Priority Claims (1)
KR 10-2018-0015486 · Feb 8, 2018 · national
Continuity (1)
Related Publication 20200400582A1 · Dec 24, 2020