Methods of making unit-dose products with supercooling
Disclosed is a method for producing a unit-dose capsule which includes optionally forming the first film into the shape of a first cavity, supercooling a first component to a temperature at which the equilibrium state of the first component is a solid or semi-solid, dispensing the first component in a supercooled state into the first cavity, such that the first component gels to form at least one layer of gel adhered to and/or in contact with the first film, forming a second film into the shape of a second cavity, filling the second cavity with a second component, sealing the first film to the second film to form a sealed cavity having at least one chamber containing the first component and the second component. The method may further include wetting and perforating the first film. The unit-dose capsule includes the sealed container and the two components.
1. A method for producing a unit dose capsule including at least one solid or semi-solid component, comprising:
forming a first film into the shape of a first cavity;
providing a first component under a first condition that makes the first component fluid and/or flowable;
dispensing the first component onto the first film or into the first cavity under a second condition such that the first component transforms to a solid or semi-solid state and forms a layer adhered to and/or in contact with the first film after dispensing;
forming a second film into the shape of a second cavity;
filling the second cavity with a second component; and
sealing the first and second films to form a sealed chamber comprising a single chamber containing the first and the second component,
wherein there is no film layer disposed in the single chamber between the first and second components such that the first and second components are disposed in contact with one another.
2. The method of claim 1 , wherein the first component is a gel and the second component is a powder.
3. The method of claim 1 , further comprising a step of wetting the first film before the dispensing step.
4. The method of claim 1 , further comprising a step of perforating the first film.
5. The method of claim 4 , wherein the first film is not perforated in a first region defined by the first component; and wherein the first film is perforated in a second region defined by the area of the first film that is 10 to 100 microns distant from the first region.
6. The method of claim 4 , wherein the perforating comprises laser perforation.
7. The method of claim 4 , wherein the perforating the first film step is completed within 0.5 to 1.0 seconds following the dispensing step.
8. The method of claim 1 , wherein the first condition is a supercooling condition.
9. The method of claim 8 , wherein, when the first component is dispensed, the first component is supercooled to a temperature 5° F. to 50° F. below the freezing temperature of the first component.
10. The method of claim 8 , wherein, when the first component is dispensed, the first component is supercooled to a temperature 20° F. to 30° F. below the freezing temperature of the first component.
11. The method of claim 8 , wherein, when the first component is dispensed, the first component is supercooled to a temperature of 125° F. to 200° F.
12. The method of claim 8 , wherein the supercooling step is completed within 0.4 seconds to 0.8 seconds.
13. The method of claim 8 , wherein the supercooling of the first component is performed in a votator.
14. The method of claim 1 , further comprising forming a second layer of gel over the first component or forming a second layer of gel adjacent to the first component.
15. The method of claim 14 , wherein the second layer of gel comprises a third component different from the first and second components.
16. The method of claim 1 , wherein the first component and the second component are positioned as layered one on top of the other.
17. The unit dose capsule of claim 1 , wherein the first component and the second component are positioned as layered side-by-side.
18. A method for producing a unit dose capsule including at least one solid or semi-solid component, comprising:
forming a first film into the shape of a first cavity;
providing a first component under a first condition that makes the first component fluid and/or flowable;
dispensing the first component onto the first film or into the first cavity under a second condition such that the first component transforms to a solid or semi-solid state and forms a layer adhered to and/or in contact with the first film after dispensing;
forming a second film into the shape of a second cavity;
filling the second cavity with a second component; and
sealing the first and second films to form a sealed chamber comprising at least one chamber containing the first and the second component,
wherein the first condition is a supercooling condition.
19. The method of claim 18 , wherein,
when the first component is dispensed, the first component is supercooled to a temperature 5° F. to 50° F. below the freezing temperature of the first component; or
when the first component is dispensed, the first component is supercooled to a temperature 20° F. to 30° F. below the freezing temperature of the first component; or
when the first component is dispensed, the first component is supercooled to a temperature of 125° F. to 200° F.
20. A method for producing a unit dose capsule including at least one solid or semi-solid component, comprising:
forming a first film into the shape of a first cavity;
providing a first component under a first condition that makes the first component fluid and/or flowable;
dispensing the first component onto the first film or into the first cavity under a second condition such that the first component transforms to a solid or semi-solid state and forms a layer adhered to and/or in contact with the first film after dispensing;
forming a second film into the shape of a second cavity;
filling the second cavity with a second component; and
sealing the first and second films to form a sealed chamber comprising a single chamber containing the first and the second component,
wherein there is no film layer disposed in the single chamber between the first and second components such that the first and second components are disposed in contact with one another,
wherein the first component is a gel and the second component is a powder,
further comprising a step of wetting the first film before the dispensing step,
further comprising a step of perforating the first film,
wherein the first film is not perforated in a first region defined by the first component; and
wherein the first film is perforated in a second region defined by the area of the first film that is 10 to 100 microns distant from the first region,
wherein the perforating comprises laser perforation,
wherein the perforating the first film step is completed within 0.5 to 1.0 seconds following the dispensing step,
wherein the first condition is a supercooling condition that is completed within 0.4 seconds to 0.8 seconds, and wherein
when the first component is dispensed, the first component is supercooled to a temperature 5° F. to 50° F. below the freezing temperature of the first component; or
when the first component is dispensed, the first component is supercooled to a temperature 20° F. to 30° F. below the freezing temperature of the first component; or
when the first component is dispensed, the first component is supercooled to a temperature of 125° F. to 200° F.