IP Library Granted Patent US 10,821,109
Granted Patent B1
US 10,821,109 · App. 16/988,508 · Granted Nov 3, 2020

Pyrazine-containing compound

Inventors: Gonul Velicelebi (San Diego, CA); Kenneth Stauderman (San Diego, CA); Michael Dunn (La Jolla, CA); Jack Roos (San Diego, CA)
Assignee: CALCIMEDICA, INC.
A61K31/497A61K31/415A61K31/4155A61K31/421A61K31/427A61K31/444A61K31/4439A61K31/485A61K31/506A61K45/06A61P1/18C07D401/04C07D405/04C07D413/14C07D417/10C07D417/14C07D491/04Y02A50/30
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Quick Facts
Patent No.
US 10,821,109
App. No.
16/988,508
Granted
Nov 3, 2020
Kind
B1
Abstract

Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

Claims (2)

1. A compound having the chemical name N-(5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable excipient thereof.

Assignments (2)
SECURITY INTEREST Recorded Mar 4, 2025
From: CALCIMEDICA, INC.
To: AVENUE CAPITAL MANAGEMENT II, L.P.
Reel/Frame 070394/0314 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 10, 2020
From: VELICELEBI, GONUL; STAUDERMAN, KENNETH; DUNN, MICHAEL; ROOS, JACK
To: CALCIMEDICA, INC.
Reel/Frame 053442/0173 →
Cited By (2)
US 12,522,589 US 12,544,371