IP Library Granted Patent US 11,021,480
Granted Patent B2
US 11,021,480 · App. 17/001,086 · Granted Jun 1, 2021

Inhibiting (α-V)(β-6) integrin

Inventors: Bryce A. Harrison (Framingham, MA); James E. Dowling (Lexington, MA); Matthew G. Bursavich (Needham, MA); Dawn M. Troast (Bedford, MA); Blaise S. Lippa (Newton, MA); Bruce N. Rogers (Belmont, MA); Cheng Zhong (Belmont, MA); Qi Qiao (Natick, MA); Fu-Yang Lin (Sudbury, MA); Brian Sosa (Cambridge, MA); Aleksey I. Gerasyuto (Flemington, NJ); Andrea Bortolato (Metuchen, NJ)
Assignee: Morphic Therapeutic, Inc.
C07D471/04A61K9/0053
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Quick Facts
Patent No.
US 11,021,480
App. No.
17/001,086
Granted
Jun 1, 2021
Kind
B2
Abstract

Disclosed are small molecule inhibitors of αvβ6 integrin, and methods of using them to treat a number of diseases and conditions.

Claims (3)

1. A compound having the formula:

or a pharmaceutically acceptable salt thereof.

2. A compound having the formula:

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2020
From: SCHRÖDINGER, INC.
To: SCHRÖDINGER, LLC
Reel/Frame 054283/0972 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2020
From: SCHRÖDINGER, LLC
To: MORPHIC THERAPEUTIC, INC.
Reel/Frame 054283/0980 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2020
From: HARRISON, BRYCE A.; DOWLING, JAMES E.; BURSAVICH, MATTHEW G.; TROAST, DAWN M.; LIPPA, BLAISE S.; ROGERS, BRUCE N.; HAHN, KRISTOPHER N.; ZHONG, CHENG; QIAO, QI; LIN, FU-YANG; SOSA, BRIAN
To: MORPHIC THERAPEUTIC, INC.
Reel/Frame 054284/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 5, 2020
From: GERASYUTO, ALEKSEY I.; BORTOLATO, ANDREA; SVENSSON, MATS A.; HICKEY, EUGENE; KONZE, KYLE D.; DAY, TYLER; KIM, BYUNGCHAN
To: SCHRÖDINGER, INC.
Reel/Frame 054284/0014 →
Continuity (4)
Continuation 16555589 · Aug 29, 2019
Provisional Application 62859457 · Jun 10, 2019
Provisional Application 62724423 · Aug 29, 2018
Related Publication 20200385384A1 · Dec 10, 2020
Cited By (4)
US 12,415,796 US 12,459,942 US 12,528,803 US 12,552,786