IP Library › Granted Patent US 11,359,214
Granted Patent B2
US 11,359,214 · App. 17/002,064 · Granted Jun 14, 2022

Simian (gorilla) adenovirus or adenoviral vectors and methods of use

Inventors: Douglas E. Brough (Gaithersburg, MD); Jason G. D. Gall (Germantown, MD); Duncan McVey (Derwood, MD)
Assignee: GenVec, Inc.
C12N15/86C07K14/005C12N7/00A61K48/00C12N2710/10322C12N2710/10333C12N2710/10343C12N2760/18034C12N2760/18522C12N2840/60
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Quick Facts
Patent No.
US 11,359,214
App. No.
17/002,064
Granted
Jun 14, 2022
Kind
B2
Abstract

The invention provides an adenovirus or adenoviral vector characterized by comprising one or more particular nucleic acid sequences or one or more particular amino acid sequences, or portions thereof, pertaining to, for example, an adenoviral pIX protein, DNA polymerase protein, penton protein, hexon protein, and/or fiber protein.

Claims (4)

1. An adenovirus or adenoviral vector comprising the nucleic acid sequence of SEQ ID NO: 21, SEQ ID NO: 23, SEQ ID NO: 24, SEQ ID NO: 25, SEQ ID NO: 26, SEQ ID NO: 27, or SEQ ID NO: 28, wherein said adenovirus or adenoviral vector comprises a non-native nucleic acid sequence.

2. The adenovirus or adenoviral vector of claim 1 , wherein said adenovirus or adenoviral vector is replication-competent.

3. The adenovirus or adenoviral vector of claim 1 , wherein said adenovirus or adenoviral vector is conditionally replication-competent.

4. The adenovirus or adenoviral vector of claim 1 , wherein said adenovirus or adenoviral vector is replication-deficient.

Assignments (2)
PATENT SECURITY AGREEMENT Recorded Sep 3, 2025
From: PRECIGEN, INC.; GENVEC LLC; PRECIGEN ACTOBIO, INC.; EXEMPLAR GENETICS, LLC
To: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
Reel/Frame 072828/0564 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2025
From: BROUGH, DOUGLAS E.; GALL, JASON G.D.; MCVEY, DUNCAN
To: GENVEC, INC.
Reel/Frame 072749/0229 →