Methods for treating melanoma
The present invention is directed to a method for preventing and/or treating melanoma such as superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma. The method comprises administering to a subject in need thereof an effective amount of dapansutrile. The method optionally comprising co-administering anti-PD-1 antibody with dapansutrile. A preferred route of administration is oral administration.
1. A method of treating melanoma in a subject, comprising the step of:
administering to the subject suffering from the melanoma an effective amount of dapansutrile, or a pharmaceutically acceptable solvate thereof.
2. The method according to claim 1 , wherein the melanoma is selected from the group consisting of: superficial spreading melanoma, nodular melanoma, lentigo maligna melanoma, and acral lentiginous melanoma.
3. The method according to claim 1 , wherein dapansutrile is administered by systemic administration.
4. The method according to claim 3 , wherein the dapansutrile is administered by oral administration.
5. The method according to claim 1 , where the method treats melanoma by reducing the size of melanoma.
6. The method according to claim 1 , further comprising administering anti-PD-1 antibody to the subject.