Treatment of intrahepatic cholestatic diseases
Treatment of intrahepatic cholestatic diseases by therapy with seladelpar or a salt thereof.
1. A method of treating an intrahepatic cholestatic disease by administering a therapeutically effective amount of a compound that is seladelpar or a salt thereof, where the amount is between 0.5 mg/day and 2 mg/day when the amount of the compound is calculated as seladelpar.
2. The method of claim 1 where the compound is seladelpar L -lysine dihydrate salt.
3. The method of claim 1 where the compound is administered orally.
4. The method of claim 1 where the amount of the compound is 0.5 mg/day, 1 mg/day, or 2 mg/day.
5. The method of claim 4 where the amount of the compound is 0.5 mg/day.
6. The method of claim 4 where the amount of the compound is 1 mg/day.
7. The method of claim 4 where the amount of the compound is 2 mg/day.
8. The method of claim 1 where the compound is administered once/day.
9. The method of claim 1 where the compound is administered between once/week and every other day.
10. The method of claim 1 where the intrahepatic cholestatic disease is primary biliary cholangitis, primary sclerosing cholangitis, progressive familial intrahepatic cholestasis, or Alagille syndrome.
11. The method of claim 10 where the intrahepatic cholestatic disease is progressive familial intrahepatic cholestasis.
12. The method of claim 10 where the intrahepatic cholestatic disease is Alagille syndrome.