Holding device for the flexible treatment of pharmaceutical packaging materials
A container holding device for holding one or more containers includes: a base plate having an upper surface, a bottom surface, and one or more holes each extending from the upper surface to the bottom surface and having a central symmetry axis L axis orthogonal to the base plate; and two or more holding elements that are located around each hole beneath the bottom surface of the base plate. The holding elements are configured to: contact an outer surface of a container that is placed into the container holding device at a bottom edge of a top region of the container, such that the container hangs in the container holding device in a first position p1 in which the holding elements do not exert any force on the outer surface of the container that is radial; and contact the outer surface of the container in a shoulder region.
1. A container holding device for holding one or more containers, the container holding device comprising:
a base plate having an upper surface and a bottom surface, the base plate comprising one or more holes, each hole extending from the upper surface to the bottom surface and having a central symmetry axis L axis orthogonal to the base plate; and
two or more holding elements that are located around each hole beneath the bottom surface of the base plate; the holding elements being configured to:
i) contact an outer surface of a container that is placed into the container holding device at a bottom edge of a top region of the container, such that the container hangs in the container holding device in a first position p1 in which the holding elements do not exert any force on the outer surface of the container that is, with respect to the central symmetry axis L axis , radial; and
ii) contact the outer surface of the container in a shoulder region of the container, thereby stabilizing the container if the container is raised upwards in the container holding device towards a second position p2.
2. The container holding device of claim 1 , wherein at least two holding elements are arranged along a circle around each hole.
3. The container holding device of claim 1 , wherein the holding elements are designed in the form of clips that are arranged obliquely below the base plate so that the clips, when an object that has a same or almost the same diameter as the hole is introduced into the hole from the upper surface of the base plate, are pushed away from the central symmetry axis L axis of the holes by the introduced object.
4. The container holding device of claim 3 , wherein the clips comprise a substantially planar inner surface that is directed towards the central symmetry axis L axis of the holes, wherein a straight line that is tangentially applied to the inner surface and that runs in a same plane as the central symmetry axis L axis of the holes includes an angle α with the central symmetry axis L axis of the holes.
5. The container of claim 4 , wherein a is in a range from 1 to 45 degrees.
6. The container of claim 5 , wherein a is in a range from 1.5 to 20 degrees.
7. The container holding device of claim 1 , further comprising one or more containers that are hanging in the first position p1.
8. The container holding device of claim 1 , further comprising one or more containers held by the container holding device, each container comprising a top region with a top edge, a bottom edge and an outer diameter d1, a neck region having an outer diameter d2<d1, a shoulder region, and a body region with an outer diameter d3>d1.
9. The container holding device of claim 8 , wherein the one or more containers is selected from a group consisting of a vial, a vartridge, an ampule, a cartridge, and a syringe.
10. The container holding device of claim 8 , wherein the holes have a diameter d4<d3.
11. The container holding device of claim 10 , wherein the diameter d4<0.95×d3.
12. The container holding device of claim 10 , wherein d4>1.25×d1.
13. The container holding device of claim 10 , wherein d1<d4<d3.
14. The container holding device of claim 8 , wherein the holes have a diameter d4>d1.
15. The container holding device of claim 14 , wherein the diameter d4<1.25×d1.
16. The container holding device of claim 8 , wherein at least one of the one or more containers protrudes with the top region beyond the upper surface of the base plate when the at least one container is raised from the first position p1 into the second position p2.
17. A kit, comprising:
a container holding device, comprising:
a base plate having an upper surface and a bottom surface, the base plate comprising one or more holes, each hole extending from the upper surface to the bottom surface and having a central symmetry axis L axis orthogonal to the base plate; and
two or more holding elements that are located around each hole beneath the bottom surface of the base plate; the holding elements being configured to:
contact an outer surface of a container that is placed into the container holding device at a bottom edge of a top region of the container, such that the container hangs in the container holding device in a first position p1 in which the holding elements do not exert any force on the outer surface of the container that is, with respect to the central symmetry axis L axis , radial; and
contact the outer surface of the container in a shoulder region of the container, thereby stabilizing the container if the container is raised upwards in the container holding device towards a second position p2;
one or more containers held by the container holding device; and
a closure system holding device that holds one or more closure systems, wherein an arrangement of the closure systems in the closure system holding device corresponds to an arrangement of the one or more containers in the container holding device.
18. The kit of claim 17 , wherein the one or more closure systems comprises a closure cap and an integrated flexible stopper.
19. The kit of claim 17 , wherein the closure system holding device comprises a base plate having an upper surface and a bottom surface, and closure system holding elements that are located at the top surface or the bottom surface of the base plate, the closure system holding elements being configured such that, when the container holding device and the closure system holding device are pressed together in order to close the one or more containers in the container holding device with the one or more closure systems in the closure system holding device, the holding elements of the container holding device are pushed away from the central symmetry axis L axis by the approaching closure system holding elements.
20. A process for producing closed containers, the process comprising:
I) providing a container holding device, wherein one or more containers having an opening at a top edge of a top region is hanging in a first position p1 in the container holding device, the container holding device comprising:
a base plate having an upper surface and a bottom surface, the base plate comprising one or more holes, each hole extending from the upper surface to the bottom surface and having a central symmetry axis L axis orthogonal to the base plate; and
two or more holding elements that are located around each hole beneath the bottom surface of the base plate; the holding elements being configured to:
contact an outer surface of the one or more containers that is placed into the container holding device at a bottom edge of the top region of the container, such that the container hangs in the container holding device in the first position p1 in which the holding elements do not exert any force on the outer surface of the container that is, with respect to the central symmetry axis L axis , radial; and
contact the outer surface of the container in a shoulder region of the container, thereby stabilizing the container if the container is raised upwards in the container holding device towards a second position p2;
II) bringing one or more of the containers from the first position p1 into the second position p2; and
III) imposing the top region of the container with a closure system comprising a closure cap and an integrated flexible stopper.