IP Library Granted Patent US 12,558,289
Granted Patent B2
US 12,558,289 · App. 17/038,226 · Granted Feb 24, 2026

Gastrointestinal treatment system including a vibrating capsule and method of use thereof

Inventors: Lior Ben-Tsur (Netanya, IL); Shai Molnar (Shorashim, IL); Roni Shabat (Kibbutz Yizra'el, IL)
Assignee: VIBRANT LTD.
A61H23/0254A61H2201/0157A61H2201/501A61H2205/08
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Quick Facts
Patent No.
US 12,558,289
App. No.
17/038,226
Granted
Feb 24, 2026
Kind
B2
Abstract

A gastrointestinal treatment system including a gastrointestinal capsule adapted to treat a subject following ingestion of the gastrointestinal capsule. The gastrointestinal capsule includes: (a) a housing; (b) a vibrating agitator, powered by the battery, the vibrating agitator adapted such that, in a first vibrating mode of operation, the housing exerts vibrations on an environment surrounding the capsule; (c) a power supply disposed within the housing and adapted to power the vibrating agitator; and (d) a controller adapted, in response to receipt of an activation input, to activate the vibrating agitator to operate in the first vibrating mode of operation at at least one predetermined time of day. The system and method may be used to treat an ailment of the gastrointestinal tract and/or to mitigate at least one symptom of jetlag in a subject travelling from an origin location to a destination location.

Claims (24)

1 . A method for treatment of a subject, the method comprising:

(a) obtaining, by the subject, a first gastrointestinal treatment system and a second gastrointestinal treatment system, each of the first and second gastrointestinal treatment systems comprising:

(i) a clock configured to provide clock-based information in the form of an hour, minute, and/or second combination; and

(ii) a gastrointestinal capsule for vibrating in a gastrointestinal tract of a subject for constipation following ingestion of said gastrointestinal capsule, said gastrointestinal capsule comprising:

(A) a housing;

(B) a vibrating agitator adapted such that, in a first vibrating mode of operation, said housing exerts vibrations on an environment surrounding said gastrointestinal capsule;

(C) a power supply disposed within said housing and adapted to power said vibrating agitator; and

(D) a programmable controller, functionally associated with the clock and programmed, in response to receipt of an activation input, to enforce activation of said vibrating agitator at a predetermined time of day by:

based on the clock-based information, computing a delay-time between the receipt of the activation input and said predetermined time of day;

waiting the computed delay-time; and

following passage of the computed delay-time, activating the vibrating agitator, such that a time at which said vibrating agitator operates in said first vibrating mode of operation is at said predetermined time of day, which coincides with a mealtime;

(b) configuring said first and second gastrointestinal treatment systems with the predetermined time of day;

(c) at a first time of day, causing activation of a first gastrointestinal capsule forming part of the first gastrointestinal system by providing a first activation input thereto, such that a first programmable controller of the first gastrointestinal capsule computes a first delay-time from said first time of day to said predetermined time of day;

(d) ingesting said first gastrointestinal capsule by the subject, wherein said first programmable controller waits said first delay-time, and following passage of said first delay-time, at a time coinciding with said predetermined time of day, activates a first vibrating agitator of said first gastrointestinal capsule to operate in said first vibrating mode of operation;

(e) at a second time of day, different from said first time of day, causing activation of a second gastrointestinal capsule forming part of the second gastrointestinal system by providing a second activation input thereto, such that a second programmable controller of the second gastrointestinal capsule computes a second delay-time from said second time of day to said predetermined time of day, the second delay-time being different from the first delay-time; and

(f) ingesting said second gastrointestinal capsule by the subject, wherein said second programmable controller waits said second delay-time, and following passage of said second delay-time, at a time coinciding with said predetermined time of day, activates a second vibrating agitator of said first gastrointestinal capsule to operate in said first vibrating mode of operation.

2 . The method of claim 1 , wherein at steps (c) and (d) occur on a first day, with respect to the predetermined time of day on said first day, and steps (e) and (f) occur on a second day, different from the first day, with respect to the predetermined time of day on said second day, and

wherein the predetermined time of day on the first day is the same time of day as the predetermined time of day on the second day.

3 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and/or said second gastrointestinal treatment systems comprises obtaining at least one gastrointestinal treatment system wherein said gastrointestinal capsule further comprises at least one sensor adapted to provide said activation input.

4 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and/or said second gastrointestinal treatment systems comprises obtaining at least one gastrointestinal treatment system wherein said clock forms part of said gastrointestinal capsule, and wherein in response to receipt of said activation input, said programmable controller is adapted to activate operation of said clock to track a time of day so as to identify said predetermined time of day for activation of said vibration agitator.

5 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and/or said second gastrointestinal treatment systems comprises obtaining at least one gastrointestinal treatment system that further comprises a control unit, adapted to provide said activation input to said programmable controller of said gastrointestinal capsule, wherein said clock forms part of said control unit.

6 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and said second gastrointestinal treatment systems comprises obtaining said first and second gastrointestinal treatment systems that include an input mechanism for receiving subject-specific input from the subject, and wherein said configuring of said first and second gastrointestinal treatment systems with said predetermined mealtime comprises configuring said first and said second gastrointestinal systems with a subject-specific mealtime of the subject, via the input mechanism.

7 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and said second gastrointestinal treatment systems comprises obtaining said first and second gastrointestinal treatment systems that include a location sensor adapted to identify a geographical region in which each of said first and second gastrointestinal capsules are located, and wherein said configuring of said first and second gastrointestinal treatment systems with said predetermined mealtime comprises configuring said first and said second gastrointestinal systems with a region-specific mealtime of said geographical region in which each of said first and second gastrointestinal capsules is located.

8 . The method of claim 1 , wherein said obtaining said first gastrointestinal treatment system and said second gastrointestinal treatment systems comprises obtaining said first and second gastrointestinal treatment systems that said programmable controller of each of said first and second gastrointestinal capsules is programmed such that said vibrating agitator operates in said first vibrating mode of operation at said predetermined time of day only if a minimum delay duration has passed between receipt of said activation input and said predetermined time of day.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2025
From: BEN-TSUR, LIOR; MOLNAR, SHAI; SHABAT, RONI
To: VIBRANT LTD.
Reel/Frame 072533/0272 →
Priority Claims (2)
GB 1805325 · Mar 30, 2018 · national
GB 1808859 · May 31, 2018 · national
Continuity (2)
Continuation In Part PCTIB2019052529 · Mar 28, 2019
Related Publication 20230059127A1 · Feb 23, 2023
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