IP Library Granted Patent US 11,259,703
Granted Patent B2
US 11,259,703 · App. 17/080,295 · Granted Mar 1, 2022

Microscopy imaging device with advanced imaging properties

Inventors: Kunal Ghosh (San Francisco, CA); Laurie D. Burns (Menlo Park, CA); Abbas El Gamal (Palo Alto, CA); Mark J. Schnitzer (Palo Alto, CA); Eric Cocker (Palo Alto, CA); Tatt Wei Ho (Stanford, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61B5/0071A61B90/20G01N21/6458G02B3/0087G02B21/008G02B21/0008G02B21/16G02B21/36G02B21/361G02B21/362G02B21/365G02B27/141G06T7/0012H04N5/2254H04N5/2256H04N5/23296A61B5/0042A61B5/0082A61B5/489A61B2090/306A61B2503/40A61B2503/42A61B2562/0233A61B2562/04A61B2576/026G06T2207/30016G06T2207/30101
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Quick Facts
Patent No.
US 11,259,703
App. No.
17/080,295
Granted
Mar 1, 2022
Kind
B2
Abstract

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm 2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

Claims (8)

1. An imaging device comprising:

a portable housing that is less than a cubic inch in size, the portable housing containing:

an excitation source configured to provide excitation light,

an optical pathway comprising a first end and a second end;

an objective lens disposed adjacent to the first end;

one or more emission elements configured and arranged to provide a focal plane adjacent to the second end from epifluorescent emission light received from the objective lens; and

an array of optical sensors positioned at the focal plane and configured and arranged to capture an image of a target object from the epifluorescent emission light,

wherein the portable housing comprises a modular design that permits individual components to be replaced.

Assignments (4)
CONFIRMATORY LICENSE Recorded Aug 14, 2026
From: STANFORD UNIVERSITY
To: NATIONAL NUCLEAR SECURITY ADMINISTRATION
Reel/Frame 075655/0923 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2022
From: GHOSH, KUNAL; BURNS, LAURIE D.; EL GAMAL, ABBAS; SCHNITZER, MARK J.; COCKER, ERIC; HO, TATT WEI
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 058835/0408 →
SECURITY INTEREST Recorded Nov 5, 2021
From: INSCOPIX, INC.
To: WTI FUND X, INC.
Reel/Frame 058828/0424 →
SECURITY INTEREST Recorded May 5, 2021
From: INSCOPIX, INC.
To: VENTURE LENDING & LEASING IX, INC.
Reel/Frame 056152/0329 →