IP Library Granted Patent US 11,957,397
Granted Patent B2
US 11,957,397 · App. 17/081,437 · Granted Apr 16, 2024

Cryogenic device with quick-connect needle probes

Inventors: Andrew Huffmaster (Fremont, CA); Erika Danielle Anderson-Bolden (Fremont, CA); Eric J. Darby (San Francisco, CA); Eric Theodore Johansson (Dublin, CA); Paul Tanaka-Roche (San Jose, CA); Jeff Gamelsky (Palo Alto, CA)
Assignee: Pacira CryoTech, Inc.
A61B18/02A61B2017/00424A61B2017/00526A61B2017/3413A61B2018/00023A61B2018/0293
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Quick Facts
Patent No.
US 11,957,397
App. No.
17/081,437
Granted
Apr 16, 2024
Kind
B2
Abstract

A cryogenic device with a cartridge holder for a cryogen cartridge, cryogen cartridge is coupleable to a cryogen pathway; a probe receptacle for receiving a needle probe, wherein the probe receptacle is configured to couple the needle probe to the cryogen cartridge via the cryogen pathway, and wherein the needle probe comprises: one or more needles having needle lumens disposed therein; a probe extension extending proximally, the probe extension having a probe lumen disposed therein, the probe lumen including an elongate element that extends from a proximal end to a distal end, wherein the probe lumen is coupled to the needle lumens at the distal end, and the cryogen pathway at a first location in between the proximal end and the distal end. Various connection mechanisms for securing needle probes to a handpiece portion are disclosed.

Claims (31)

1. A cryogenic device comprising:

a cartridge holder for holding a cryogen cartridge comprising a cryogen, wherein the cryogen cartridge is coupleable to a cryogen pathway; and

a probe receptacle configured to receive a needle probe, wherein the probe receptacle is configured to couple the needle probe to the cryogen cartridge via the cryogen pathway, and wherein the needle probe comprises:

one or more needles each having a needle lumen disposed therein;

a first sealing element at a proximal side of a first location;

a second sealing element at a distal side of the first location;

a supply valve between the cryogen cartridge and the second sealing element, the supply valve configured to transition from an open position to a closed position; and

a probe extension extending proximally, the probe extension having a probe lumen disposed therein, the probe lumen including an elongate element that extends from a proximal end to a distal end, wherein the probe lumen is coupled to:

the needle lumens at the distal end, and

an inlet of the cryogen pathway at the first location in between the proximal end and the distal end so as to reduce an outward force on the needle probe,

wherein the first sealing element and the second sealing element seal the proximal end and the distal end of the probe receptacle from venting to ambient air when the supply valve is in the open position and when the supply valve is in the closed position, and wherein the first sealing element and the second sealing element do not translate with the supply valve in the open position and the closed position so as to stabilize pressure within the probe receptacle.

2. The cryogenic device of claim 1 , wherein the first and second sealing elements are configured to seal the probe receptacle at the proximal and distal sides of the first location.

3. The cryogenic device of claim 2 , wherein the first and second sealing elements are O-rings.

4. The cryogenic device of claim 1 , wherein the supply valve is disposed along the cryogen pathway between the cryogen cartridge and the probe receptacle.

5. The cryogenic device of claim 1 , wherein the cryogen pathway comprises a bore through an internal chassis, wherein an interior surface of the cryogen pathway comprises a metal material configured to reduce formation of bubbles from vaporization of the cryogen.

6. The cryogenic device of claim 1 , wherein the cartridge holder and the probe receptacle are housed in a handpiece capable of being held by a user.

7. The cryogenic device of claim 6 , further comprising a piercing point integrated into the handpiece, wherein the piercing point is configured to pierce the cryogen cartridge when the cryogen cartridge is disposed within the cartridge holder.

8. The cryogenic device of claim 6 , wherein the handpiece comprises an elongate housing extending along an axis, the elongate housing of the handpiece comprising a movable cartridge door fixed to the elongate housing along the axis of the elongate housing, wherein the cartridge door is configured to move from an open position for allowing the cartridge holder to receive the cryogen cartridge to a closed position for securing the cryogen cartridge within the elongate housing.

9. The cryogenic device of claim 8 , wherein the cartridge door is fixed to the elongate housing such that it is configured to swivel from the open position to the closed position.

10. The cryogenic device of claim 6 , wherein the handpiece comprises an elongate housing extending along an axis, and wherein the handpiece is configured to rest substantially horizontally along the axis on a charging cradle to receive charging energy from the charging cradle.

11. The cryogenic device of claim 6 , further comprising a processor located within the handpiece, wherein the processor is configured to receive a probe descriptor information from the needle probe, wherein the processor is further configured to determine that the needle probe is of a first probe type of a plurality of probe types.

12. The cryogenic device of claim 1 , further comprising a passageway terminating at a proximal end of the probe extension, wherein the passageway is exposed to ambient air such that the proximal end of the probe extension is exposed to ambient air.

13. The cryogenic device of claim 1 , wherein the one or more needles include one or more depressions or projections configured to make one or more portions of the needles echogenic so as to allow for visualization of the needles using ultrasound.

14. The cryogenic device of claim 13 , wherein the depressions or projections have a polygonal design.

15. A cryogenic device comprising:

a cartridge holder for holding a cryogen cartridge comprising a cryogen, wherein the cryogen cartridge is coupleable to a cryogen pathway;

a probe receptacle configured to receive a probe extension of a needle probe, the probe extension having a proximal end and a distal end, wherein the probe receptacle is configured to receive the proximal end of the probe extension, and wherein the probe receptacle comprises:

a first sealing element and a second sealing element for sealing the probe receptacle;

a supply valve between the cryogen cartridge and the second sealing element, the supply valve configured to transition from an open position to a closed position; and

a probe receptacle configured to, when the probe extension is secured to the probe receptacle, couple a lumen of the probe extension to an inlet of the cryogen pathway and introduce the cryogen into the lumen of the probe extension, wherein the probe receptacle couples to the inlet of the cryogen pathway at a first location between the proximal end and the distal end of the probe extension, wherein the first location is disposed between the first sealing element and the second sealing element,

wherein the first sealing element and the second sealing element seal the proximal end and the distal end of the probe receptacle from venting to ambient air when the supply valve is in the open position and when the supply valve is in the closed position, and wherein the first sealing element and the second sealing element do not translate with the supply valve in the open position and the closed position so as to stabilize pressure within the probe receptacle.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Dec 5, 2025
From: JPMORGAN CHASE BANK, N.A.
To: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
Reel/Frame 073779/0532 →
TERMINATION AND RELEASE OF SECURITY INTEREST IN PATENTS Recorded Mar 31, 2023
From: JPMORGAN CHASE BANK, N.A.
To: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
Reel/Frame 063213/0864 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Mar 31, 2023
From: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; PACIRA THERAPEUTICS, INC. (F/K/A FLEXION THERAPEUTICS, INC.)
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 063214/0108 →
SUPPLEMENTAL CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Dec 14, 2021
From: PACIRA CRYOTECH, INC.; PACIRA PHARMACEUTICALS, INC.; FLEXION THERAPEUTICS, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 058516/0636 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2021
From: HUFFMASTER, ANDREW; ANDERSON-BOLDEN, ERIKA DANIELLE; DARBY, ERIC J.; JOHANSSON, ERIC THEODORE; TANAKE-ROCHE, PAUL; GAMELSKY, JEFF
To: PACIRA CRYOTECH, INC.
Reel/Frame 054932/0881 →
Cited By (2)
US 12,551,258 US 12,708,422