IP Library Granted Patent US 11,510,377
Granted Patent B2
US 11,510,377 · App. 17/081,582 · Granted Nov 29, 2022

Polynucleotides and methods for transferring resistance to Asian soybean rust

Inventors: Greg Rairdan (Wilmington, DE); Karen Broglie (Landenberg, PA); Gilda Rauscher (Johnston, IA); Hendrikus Pieter van Esse (Norwich, GB); Jonathan D. G. Jones (Norwich, GB); Cintia Goulart Kawashima (Norfolk, GB); Sergio Herminio Brommonschenkel (Vicosa, BR)
Assignees: Two Blades Foundation; E. I. Du Pont De Nemours aand Company; Universidade Federal De Vicosa
A01H1/04A01H1/02A01N25/00A01N65/20C07K14/415C12N15/8282
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Quick Facts
Patent No.
US 11,510,377
App. No.
17/081,582
Granted
Nov 29, 2022
Kind
B2
Abstract

Disclosed herein are compostions and methods for improving or enhancing pathogen resistance in legume plants. Compositions comprising polypeptides encoded by legume-derived nucleotide-binding site-leucine-rich repeat (NB-LRR) genes are useful in improving resistance in legumes to Asian soybean rust. Methods of using NB-LRR genes can be used to make a transgenic resistant legume plant.

Claims (12)

1. A recombinant DNA construct comprising a heterologous regulatory element operably linked to a polynucleotide comprising a nucleotide sequence encoding a legume-derived nucleotide binding site-leucine-rich repeat (NB-LRR) polypeptide having at least 90% amino acid sequence identity to SEQ ID NO: 2.

2. A method of conferring disease resistance in a legume crop species, the method comprising transforming a legume crop species with a polynucleotide comprising a nucleotide sequence encoding a legume-derived nucleotide-binding site-leucine-rich repeat (NB-LRR) polypeptide having at least 90% amino acid sequence identify to SEQ ID NO: 2 that confers disease resistance to a legume crop species disease.

3. The method of claim 2 , wherein the legume crop species disease is caused by a plant pathogen.

4. The method of claim 3 , wherein the plant pathogen is Phakopsora pachyrhizi or Phakopsora meibomiae.

5. The method of claim 2 , wherein the legume crop species disease is Asian soybean rust.

6. The method of claim 2 , wherein the legume crop species is an alfalfa, clover, pea, bean lentil, lupin, mesquite, carob, soybean, peanut or tamarind.

7. The method of claim 2 , wherein the legume crop species is soybean.

8. A method of enhancing plant resistance to Asian soybean rust (ASR) disease, the method comprising conferring resistance to an ASR pathogen by introgression of a polynucleotide comprising a nucleotide sequence encoding a legume-derived nucleotide-binding site-leucine-rich repeat (NB-LRR) polypeptide having at least 90% amino acid sequence identify to SEQ ID NO: 2 into germplasm in a breeding program for resistance to ASR.

9. The method of claim 8 , where in the germplasm is an alfalfa, clover, pea, bean, lentil, lupin, mesquite, carob, soybean, peanut or tamarind species.

10. The method of claim 8 , wherein the ASR is caused by Phakopsora pachyrhizi or Phakopsora meibomiae.

11. The recombinant DNA construct of claim 1 , further comprising one or more resistance genes.

12. The recombinant DNA construct of claim 11 , further comprising one or more polynucleotide sequences of interest.

Assignments (5)
NUNC PRO TUNC ASSIGNMENT Recorded Nov 29, 2022
From: E.I. DU PONT DE NEMOURS AND COMPANY
To: CORTEVA AGRISCIENCE LLC
Reel/Frame 063141/0155 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: JONES, JONATHAN D.G.; KAWASHIMA, CINTIA G.
To: TWO BLADES FOUNDATION
Reel/Frame 061059/0024 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: VAN ESSE, HENDRIKUS PIETER
To: TWO BLADES FOUNDATION
Reel/Frame 061059/0030 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: RAIRDAN, GREG; BROGLIE, KAREN; RAUSCHER, GILDA
To: E. I DUPONT DE NEMOURS AND COMPANY
Reel/Frame 061059/0040 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2022
From: HERMINIO BROMMONSCHENKEL, SERGIO
To: UNIVERSIDADE FEDERAL DE VICOSA
Reel/Frame 061059/0049 →
Continuity (3)
Continuation 15573149
Provisional Application 62159718 · May 11, 2015
Related Publication 20210051869A1 · Feb 25, 2021