System and method for detection of target substances
A system and method for detecting harmful substances within a consumable sample comprising: receiving a consumable sample at a first chamber of a test container; transforming the consumable sample into a homogenized sample upon processing of the consumable sample; delivering the homogenized sample to a second chamber of the test container, wherein the second chamber is configured to receive the homogenized sample comprises an outlet port; mixing the homogenized sample with a process reagent within the second chamber, thereby producing a dispersion; transmitting a volume of the dispersion to an analysis chamber, of the test container, configured to position a detection substrate proximal the port of the second chamber and comprising a detection window that enables detection of presence of the allergen; and detecting presence of the allergen within the consumable sample by way of an optical sensor configured to detect signals indicative of the allergen through the detection window.
1. A system with a test container for detecting an allergen in a consumable sample, the test container comprising:
a first chamber configured to receive the consumable sample including the allergen, the consumable sample being a food sample;
a second chamber configured to receive a homogenized sample, the homogenized sample produced from the consumable sample, from the first chamber;
a separator situated between the first chamber and the second chamber, wherein the separator is configured to control entry of the homogenized sample into the second chamber;
an analysis chamber that enables detection of a presence of the allergen, the analysis chamber fluidly coupled to the second chamber; and
a detection substrate that includes a test strip, the detection substrate being positioned within the analysis chamber and entirely outside the second chamber, the detection substrate being configured to soak up a portion of the homogenized sample to detect the allergen.
2. The system of claim 1 , wherein the system further comprises a homogenizing element configured to interact with the first chamber and to generate a homogenized sample.
3. The system of claim 1 , wherein in a first configuration, the separator retains at least a portion of the homogenized sample within the separator.
4. The system of claim 3 , wherein the separator is operable in at least the following configurations:
a first configuration that precludes entry of the homogenized sample into the second chamber; and
a second configuration that facilitates entry of the homogenized sample into the second chamber.
5. The system of claim 1 , wherein the analysis chamber enables detection of the presence of the allergen by way of inspection of the detection substrate through a detection window.
6. The system of claim 5 , further comprising an analysis device, the analysis device comprising:
a receiving port configured to reversibly receive the test container in a received configuration; and
an optical sensor aligned with the detection window of the analysis chamber in the received configuration.
7. The system of claim 6 , wherein the system is in communication with a processing system configured to receive signals from the optical sensor and to generate an output indicative of the presence of the allergen within the consumable sample.
8. The system of claim 7 , wherein the processing system is onboard the analysis device.
9. The system of claim 5 , wherein the detection substrate comprises at least one active region comprising antibody-treated particles, configured to bind to analytes associated with the allergen, thereby facilitating detection of presence of the allergen.
10. The system of claim 7 , wherein the optical sensor comprises a camera module configured to detect image intensity, indicative of an amount of analytes associated with the allergen, at the detection substrate.
11. The system of claim 5 , wherein the detection window of the analysis chamber is configured to provide indication of at least one of heat damage and humidity damage to the detection substrate.
12. A test container comprising:
a first chamber configured to receive a food sample including an allergen, the first chamber including an opening to receive the food sample, wherein when the food sample is positioned in the first chamber a reagent combines with the food sample to create a mixture;
a second chamber configured to receive the mixture from the first chamber;
a separator positioned between the first chamber and the second chamber, the separator positioned below the opening, wherein the separator is configured to allow passage of the mixture from the first chamber and into the second chamber;
an analysis chamber fluidly coupled to the second chamber; and
a detection substrate positioned within the analysis chamber and entirely outside of the second chamber, the detection substrate being configured to detect the allergen, the detection substrate including a test strip.
13. The test container of claim 12 , further comprising:
a port positioned between the second chamber and the analysis chamber, the port fluidly coupling the second chamber to the analysis chamber; and
wherein the detection substrate is vertical; and
wherein the detection substrate is configured to soak up a portion of the mixture to detect the allergen.
14. The test container of claim 13 , wherein the detection substrate includes an antibody complementary to the allergen to provide an indication of a presence of the allergen.
15. The test container of claim 14 , wherein the allergen includes gluten.
16. The test container of claim 12 , further comprising a driving element having threads;
wherein the first chamber includes threads;
wherein the driving element is configured to screw onto the test container via the threads of the driving element and the threads of the first chamber.
17. A test container comprising:
a first chamber configured to receive a food sample that includes an allergen;
a second chamber configured to receive a homogenized sample, the homogenized sample produced from the food sample in the first chamber;
a separator situated between the first chamber and the second chamber, wherein the separator is configured to control entry of the homogenized sample into the second chamber;
an analysis chamber that enables detection of a presence of the allergen;
a test strip positioned entirely outside of the second chamber and within the analysis chamber, the test strip being configured to soak up a portion of the homogenized sample to detect the allergen;
wherein the analysis chamber includes a detection window in alignment with the test strip that is configured to enable detection of the presence of the allergen; and
wherein a longitudinal axis of the test strip is parallel relative to a longitudinal axis of the first chamber or the second chamber.
18. The test container of claim 17 , wherein the allergen includes gluten.
19. The test container of claim 17 , further comprising a driving element that threadingly engages with the first chamber of the test container.
20. The test container of claim 17 , further comprising a port positioned between the second chamber and the analysis chamber, the port fluidly coupling the second chamber to the analysis chamber; and
wherein a portion of the test strip is positioned above the port.