IP Library Granted Patent US 11,744,561
Granted Patent B2
US 11,744,561 · App. 17/092,262 · Granted Sep 5, 2023

Saliva collection and testing system

Inventors: Renjith Menon (Campbell, CA); Loc Phan (Santa Clara, CA); Nichole Garcia (Laguna Beach, CA)
Assignee: Smylio Inc.
A61B10/0051A61B5/14507A61B5/14539A61B5/14546A61B5/4875A61B5/682A61B2560/04
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Quick Facts
Patent No.
US 11,744,561
App. No.
17/092,262
Granted
Sep 5, 2023
Kind
B2
Abstract

A system with a saliva sampling device configured to be orally worn by a patient. The saliva sampling device is a polymer retainer or aligner. A saliva analysis engine is used to correlate one or more analytes of one or more saliva samples with one or more health attributes. A health monitoring engine updates a health profile of the patient based on the correlated health attributes.

Claims (25)

1. A health monitoring system comprising:

one or more processors;

memory coupled to the one or more processors, the memory comprising instructions, which when executed by the one or more processors, cause the one or more processors to:

receive data for at least one analyte sourced from at least one saliva sample collected by a saliva sampling device configured to be orally worn by a patient, wherein the saliva sampling device comprises one of: a polymer retainer and a polymer aligner;

correlate the at least one analyte of the at least one saliva sample with at least one health attribute, wherein the at least one saliva sample is collected by the saliva sampling device over a plurality of days during incremental wearing periods of the saliva sampling device by the patient, wherein the at least one saliva sample is collected by the saliva sampling device at one or more time periods initiated by user action with the saliva sampling device that enables sampling of saliva, wherein the user action comprises at least one selected from the group consisting of: removal of a cover on a storage access location on the saliva sampling device, and application of force to the saliva sampling device; and

update a health profile of the patient based on the at least one health attribute.

2. The system of claim 1 , wherein the health profile comprises at least one profile for at least one health condition, and wherein the at least one health attribute is used to update the at least one status profile.

3. The system of claim 1 , wherein the health profile comprises at least one risk profile for at least one disease, and wherein the at least one correlated attribute is used to update the at least one risk profile.

4. The system of claim 1 , wherein the health profile comprises at least one nutrition profile for at least one nutritional aspect, and wherein the at least one health attribute is used to update the at least one nutrition profile.

5. The system of claim 1 , wherein each of the incremental wearing periods is at least one hour.

6. The system of claim 1 , wherein the at least one saliva sample is one of a plurality of saliva samples collected by the saliva sampling device over a plurality of days.

7. The system of claim 1 , wherein the at least one health attribute is processed to provide one or more of: nutritional information, disease information, hormone information, and genetic information.

8. The system of claim 7 , wherein the nutritional information comprises one or more of: hydration information, PH level information, fluoride information, mineralization information, alcohol information, and microbiome information.

9. The system of claim 8 , wherein the disease information comprises one or more of: infectious disease information, cancer information, inflammation information, and virus information.

10. The system of claim 1 , wherein the at least one analyte comprises at least one biomarker of the at least one saliva sample.

11. The system of claim 1 , wherein the executed instructions further cause the one or more processors to correlate the at least one analyte of the at least one saliva sample with at least one genetic attribute.

12. The system of claim 1 , wherein the executed instructions further cause the one or more processors to store the health profile.

13. The system of claim 1 , wherein the executed instructions further cause the one or more processors to provide health monitoring updates and/or alerts to at least one access device.

14. The system of claim 1 , wherein the saliva sampling device is one of a plurality of saliva sampling devices, and wherein the health profile is updated and maintained from a plurality of correlated health attributes derived from a plurality of saliva samples collected by the plurality of saliva sampling devices.

15. The system of claim 1 , wherein the saliva sampling device comprises at least one biosensor.

16. The system of claim 1 , wherein the saliva sampling device comprises a plurality of saliva storage portions configured to store the at least one saliva sample over the plurality of days, and wherein the plurality of saliva storage portions comprises at least one saliva storage portion that is enabled by application of force by a user.

17. The system of claim 1 , wherein the saliva sampling device comprises at least one communication device configured to wirelessly connect with a network and/or a network access device, wherein the saliva sampling device wireless transmits the data to the one or more processors, the data being indicative or non-indicative of the at least one analyte.

18. The system of claim 1 , wherein the user action comprises the application of force to the saliva sampling device by a user.

19. The system of claim 1 , wherein the user action comprises the removal of a cover on a storage access location on the saliva sampling device by a user, and wherein the storage access location comprises an opening in a portion of the saliva sampling device.

20. The system of claim 1 , wherein the saliva sampling device comprises a plurality of saliva storage portions configured to store the at least one saliva sample over the plurality of days, and wherein each saliva storage portion of the plurality of saliva storage portions is configured to be user enabled by at least one user action selected from the group consisting of: removal of a cover on a storage access location on the saliva sampling device, and application of force to the saliva sampling device.

Assignments (4)
SECURITY INTEREST Recorded Aug 30, 2024
From: SMYLIO INC.
To: WESTERN ALLIANCE BANK
Reel/Frame 068456/0676 →
RELEASE OF SECURITY INTEREST Recorded Aug 24, 2023
From: WELCOMMERCE FUNDING LLC
To: SMYLIO INC.
Reel/Frame 064698/0088 →
SECURITY INTEREST Recorded Oct 25, 2021
From: SMYLIO INC.
To: WELCOMMERCE FUNDING LLC
Reel/Frame 057898/0583 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 6, 2021
From: MENON, RENJITH; PHAN, LOC; GARCIA, NICHOLE
To: SMYLIO INC.
Reel/Frame 057717/0906 →
Continuity (2)
Provisional Application 62932396 · Nov 7, 2019
Related Publication 20210137503A1 · May 13, 2021