IP Library › Granted Patent US 12,295,648
Granted Patent B2
US 12,295,648 · App. 17/099,272 · Granted May 13, 2025

Method and apparatus for rapid and safe pulmonary vein cardiac ablation

Inventors: Gary Long (Cincinnati, OH); Raju Viswanathan (Mountain View, CA)
Assignee: Boston Scientific Scimed, Inc.
A61B18/1492A61B18/1206A61B2017/00477A61B2017/00876A61B2018/00351A61B2018/00363A61B2018/00375A61B2018/00642A61B2018/00827A61B2018/00839A61B2018/00875A61B2018/00892A61B2018/124A61B2018/1405A61B2018/1435A61M25/0127
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Quick Facts
Patent No.
US 12,295,648
App. No.
17/099,272
Granted
May 13, 2025
Kind
B2
Abstract

An apparatus includes a shaft, the shaft including a plurality of stepped sections along the length of the shaft. The apparatus further includes a plurality of electrodes disposed along the length of the shaft, each electrode characterized by a geometric aspect ratio of the length of the electrode to the outer diameter of the electrode. Each electrode is located at a different stepped section of the plurality of stepped sections of the shaft and includes a set of leads. Each lead of the set of leads is configured to attain an electrical voltage potential of at least about 1 kV. The geometric aspect ratio of at least one electrode of the plurality of electrodes is in the range between about 3 and about 20.

Claims (30)

1. An apparatus, comprising:

a shaft including a plurality of stepped sections separated by gaps along a length of the shaft, wherein the shaft at each stepped section of the plurality of stepped sections has an outer diameter that is less than an outer diameter of the shaft at the gaps;

a plurality of electrodes disposed along the length of the shaft, each electrode characterized by a geometric aspect ratio of a length of the electrode to an outer diameter of the electrode, each electrode located on a different stepped section of the plurality of stepped sections of the shaft such that an outer surface of the apparatus including the plurality of electrodes and the gaps forms a smooth profile of constant diameter, the plurality of electrodes configured to generate an electric field to ablate tissue via irreversible electroporation,

each electrode of the plurality of electrodes coupled to a lead of a set of leads, each lead of the set of leads configured to attain an electrical voltage potential of at least about 1 kV without resulting in dielectric breakdown for generating the electric field,

wherein the geometric aspect ratio of at least one electrode of the plurality of electrodes is in the range between about 3 and about 20 to reduce a peak value of an intensity of the electric field;

a distal attachment mechanism having a distal magnetic member disposed in a distal portion of the shaft and configured to couple to a second catheter.

2. The apparatus of claim 1 , wherein at least one electrode of the plurality of electrodes includes a coiled length of an electrical conductor.

3. The apparatus of claim 1 , the shaft further including a lumen formed therein, the apparatus configured for, when a guidewire is disposed in the lumen during use, movement along the guidewire.

4. The apparatus of claim 1 , the shaft further including an intermediate magnetic member disposed in an intermediate portion of the shaft and configured to connect with a secondary catheter associated with the second catheter.

5. The apparatus of claim 4 , wherein the intermediate magnetic member disposed in the intermediate portion of the shaft includes an electromagnet.

6. The apparatus of claim 1 , wherein the distal magnetic member disposed in the distal portion of the shaft includes one magnetic pole oriented substantially longitudinally and one magnetic pole oriented substantially laterally with respect to an elongate axis of the shaft.

7. The apparatus of claim 1 , the shaft further including two or more channels, each channel continuous from a proximal portion of the shaft to a lateral exit position on the shaft.

8. The apparatus of claim 7 , wherein the two or more channels are configured for passage of secondary catheters.

9. The apparatus of claim 1 , wherein the geometric aspect ratio of at least one electrode of the plurality of electrodes is in the range between about 5 and about 10.

10. The apparatus of claim 1 , further comprising a pulse generator configured to generate a pulsed waveform having an amplitude of at least about 0.5 kV,

the plurality of electrodes configured to generate the electric field in response to receiving the pulsed waveform.

11. The apparatus of claim 10 , wherein a strength of the electric field is at least about 200 V/cm.

12. An apparatus, comprising:

a catheter shaft including a plurality of stepped sections separated by gaps along a length of the shaft, wherein the shaft at each stepped section of the plurality of stepped sections has an outer diameter that is less than an outer diameter of the shaft at the gaps;

a set of flexible electrodes disposed along a length of the catheter shaft, each flexible electrode of the set of flexible electrodes characterized by a geometric aspect ratio of a length of the flexible electrode to an outer diameter of the flexible electrode, each flexible electrode of the set of flexible electrodes including a set of conducting rings, each of the conducting rings of the set of conducting rings separated by a section of catheter shaft and disposed along the catheter shaft, the set of conducting rings of each flexible electrode of the set of flexible electrodes electrically connected together so as to electrically define a common electrical potential for the each flexible electrode, adjacent flexible electrodes of the set of flexible electrodes separated by the gaps, each electrode located on a different stepped section of the plurality of stepped sections of the shaft such that an outer surface of the apparatus including the plurality of electrodes and the gaps forms a smooth profile of constant diameter, the set of flexible electrodes configured to generate an electric field to ablate tissue via irreversible electroporation; and

electrical leads attached to each of the flexible electrodes, each electrical lead configured for attaining an electrical voltage potential of at least 1 kV for generating the electric field,

wherein the geometric aspect ratio of at least one of the flexible electrodes is in the range between about 3 and about 20 to reduce a peak value of an intensity of the electric field;

a distal attachment mechanism having a distal magnetic member disposed in a distal portion of the shaft and configured to couple to a second catheter.

13. The apparatus of claim 12 , wherein a width of each conducting ring of the set of conducting rings of each flexible electrode of the set of flexible electrodes is in the range between about 0.5 mm and about 6 mm.

14. The apparatus of claim 13 , wherein the width of adjacent conducting rings of the set of conducting rings of each flexible electrode of the set of flexible electrodes is different.

15. The apparatus of claim 12 , wherein the space between adjacent conducting rings of the set of conducting rings of each flexible electrode of the set of flexible electrodes is in the range between about 1 mm and about 4 mm.

16. The apparatus of claim 12 , wherein the gaps between adjacent flexible electrodes of the set of flexible electrodes may be in the range between about 2 mm and about 12 mm.

17. The apparatus of claim 12 , further comprising a pulse generator configured to generate a pulsed waveform having an amplitude of at least about 0.5 kV,

the plurality of electrodes configured to generate the electric field in response to receiving the pulsed waveform.

18. The apparatus of claim 17 , wherein a strength of the electric field is at least about 200 V/cm.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2022
From: FARAPULSE, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 060802/0286 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2020
From: GLL, LLC; LONG, GARY L.
To: IOWA APPROACH, INC.
Reel/Frame 054389/0919 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2020
From: VISWANATHAN, RAJU
To: IOWA APPROACH, INC.
Reel/Frame 054389/0984 →
CHANGE OF NAME Recorded Nov 17, 2020
From: IOWA APPROACH, INC.
To: FARAPULSE, INC.
Reel/Frame 054449/0429 →
Continuity (4)
Continuation 15484969 · Apr 11, 2017
Continuation PCTUS2015055105 · Oct 12, 2015
Provisional Application 62122152 · Oct 14, 2014
Related Publication 20210077188A1 · Mar 18, 2021
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