IP Library › Patent Application 17101005
Patent Application
App. No. 17/101,005

FIBRINOGEN COMPOSITION, METHOD AND WOUND ARTICLES

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
17/101,005
Filed
Nov 23, 2020
Art Unit
1611
USPC
424/443
Abstract

Disclosed is a fibrinogen composition. The fibrinogen composition comprises denatured fibrinogen hydrogel having a fibrinogen concentration ranging from 0.1 to 15 wt.-% and a fibrinogen hydrogel forming salt at a concentration less than a threshold concentration to form the fibrinogen hydrogel. In some examples, the fibrinogen composition is dehydrated denatured fibrinogen hydrogel, where the fibrinogen composition comprises salt at a concentration no greater than 20 wt.-%.

Claims (24)

1 . A fibrinogen composition comprising

denatured fibrinogen hydrogel having a fibrinogen concentration ranging from 0.1 to 15 wt.-%;

fibrinogen hydrogel forming salt at a concentration less than a threshold concentration to form the fibrinogen hydrogel.

2 . The fibrinogen composition of claim 1 , wherein the fibrinogen composition comprises at least 50 wt.-% water.

3 . The fibrinogen composition of claim 1 , wherein the fibrinogen hydrogel forming salt concentration is less than 0.45 wt-% of the fibrinogen composition.

4 . The fibrinogen composition of claim 1 , wherein the fibrinogen hydrogel forming salt comprises sodium citrate optionally in combination with sodium chloride.

5 . The fibrinogen composition of claim 1 , further comprising a plasticizer.

6 . The fibrinogen composition of claim 5 wherein the plasticizer comprises a sugar alcohol, an alkane diol, or a combination thereof.

7 . The fibrinogen composition of claim 1 , further comprising a carrier material in an amount ranging from 0.1 to about 50 wt.-%.

8 . The fibrinogen composition of claim 7 wherein the carrier material comprises a water-soluble polymer.

9 . The fibrinogen composition of claim 8 , wherein the water-soluble polymer comprises polymerized units of N-vinyl lactam polymer.

10 . The fibrinogen composition of claim 7 , wherein the carrier material further comprises a swelling agent.

11 . The fibrinogen composition of claim 1 , wherein the fibrinogen composition is at least partially dehydrated.

12 . A fibrinogen composition comprising

dehydrated denatured fibrinogen hydrogel;

wherein the fibrinogen composition comprises salt at a concentration no greater than 20 wt.-%.

13 . The fibrinogen composition of claim 12 , wherein the fibrinogen composition comprises at least 5 wt.-% fibrinogen.

14 . The fibrinogen composition of claim 12 , wherein the fibrinogen composition comprises less than 50 wt.-% water.

15 . The fibrinogen composition of claim 12 , wherein the salt concentration is less than 15, 10, or 5 wt.-% of the fibrinogen composition.

16 . The fibrinogen composition of claim 12 , further comprising a plasticizer.

17 . The fibrinogen composition of claim 12 , further comprising a carrier material.

18 . The fibrinogen composition of claim 17 , wherein the fibrinogen composition is interdispersed with 0.5 to 99 wt.-% of the carrier material.

19 . The fibrinogen composition of claim 17 , wherein the fibrinogen composition is disposed on the carrier material.

20 . The fibrinogen composition of claim 17 , wherein the carrier material comprises a water-soluble polymer.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2024
From: 3M INNOVATIVE PROPERTIES COMPANY
To: SOLVENTUM INTELLECTUAL PROPERTIES COMPANY
Reel/Frame 066443/0600 →