Stabilizing pressure in cryogenic devices

1. A method for stabilizing pressure within a cryogenic device during a cryotherapy treatment, the method comprising:

receiving a first flow rate value, wherein the first flow rate value corresponds to an expected average mass flow rate of a cryogen through a first needle probe of the cryogenic device during a cryotherapy treatment cycle;

determining, based on the first flow rate value, a first target heater power to be applied to a heater associated with the cryogenic device for a first treatment cycle, wherein the heater is configured to heat the cryogen;

receiving an input for the first treatment cycle;

causing the cryogen to flow for a period of time toward the first needle probe in response to the input;

applying the first target heater power to the heater during the first treatment cycle so as to cause the heater to heat the cryogen and stabilize pressure within the cryogenic device during or after the first treatment cycle;

receiving pressure data from a pressure sensor of the cryogenic device during the first treatment cycle;

calculating, based on the received pressure data, an average rate of change in pressure during a cooling phase of the first treatment cycle; and

calculating a second target heater power for a second treatment cycle, wherein the second target heater power is calculated at least in part by adjusting the first target heater power upward or downward by an adjustment value based on the average rate of change in pressure.

2. The method of claim 1 , wherein the first target heater power is defined such that an average rate of change in pressure during a cooling phase of the first treatment cycle remains within a predetermined range.

3. The method of claim 1 , wherein the first flow rate value is received by a processor of the cryogenic device from the first needle probe.

4. The method of claim 1 , wherein the heater is coupled to a cryogen cartridge associated with the cryogenic device, wherein the cryogenic device comprises a handpiece portion, and wherein the cryogen cartridge and the first needle probe are directly coupled to the handpiece portion, a cryogen pathway extending between the cryogen cartridge and the first needle probe.

5. The method of claim 1 , further comprising:

determining a target duty cycle necessary for applying the first target heater power;

wherein applying the first target heater power engages the heater for the target duty cycle.

6. The method of claim 1 , wherein applying the first target heater power comprises adjusting an amount of current or voltage applied to the heater.

7. The method of claim 1 , further comprising determining that the average rate of change in pressure is negative and beyond a predetermined range, wherein the second target heater power is calculated at least in part by adjusting the first target heater power upward by the adjustment value.

8. The method of claim 1 , further comprising determining that the average rate of change in pressure is positive and beyond a predetermined range, wherein the second target heater power is calculated at least in part by adjusting the first target heater power downward by the adjustment value.

9. The method of claim 1 , wherein the adjustment value is determined based on a magnitude of the average rate of change in pressure.

10. The method of claim 1 , further comprising:

determining that the average rate of change in pressure has a magnitude greater than a threshold magnitude;

based on the determination, generating a notification indicating an issue with the cryogenic device.

11. The method of claim 10 , wherein the average rate of change in pressure is negative, and wherein the notification identifies the issue as a depleted cryogen source based on the average rate of change in pressure.

12. The method of claim 10 , wherein the average rate of change in pressure is positive, and wherein the notification identifies the issue as a blocked or impeded cryogen pathway based on the average rate of change in pressure.

13. The method of claim 1 , wherein the first treatment cycle comprises a cooling phase and a recovery phase, and wherein the first target heater power is applied during the cooling phase.

14. A method for stabilizing pressure within a cryogenic device during a cryotherapy treatment, the method comprising:

receiving a first flow rate value, wherein the first flow rate value corresponds to an expected average mass flow rate of a cryogen through a first needle probe of the cryogenic device during a cryotherapy treatment cycle;

determining, based on the first flow rate value, a first target heater power to be applied to a heater associated with the cryogenic device for a first treatment cycle, wherein the heater is configured to heat the cryogen;

receiving an input for the first treatment cycle;

causing the cryogen to flow for a period of time toward the first needle probe in response to the input;

applying the first target heater power to the heater during the first treatment cycle so as to cause the heater to heat the cryogen and stabilize pressure within the cryogenic device during or after the first treatment cycle; and

determining a target duty cycle necessary for applying the first target heater power, wherein applying the first target heater power engages the heater for the target duty cycle;

wherein the target duty cycle is determined based on an output of an equation: Duty Cycle=P Target ×(R Heater /V Heater 2 ), wherein P Target is the first target heater power, R Heater is a resistance of the heater, and V Heater is a voltage across the heater, further comprising monitoring a voltage of a power source coupled to the heater so as to estimate a real-time value for V Heater .

15. The method of claim 14 , further comprising:

replacing the first needle probe with a second needle probe;

receiving a second flow rate value, wherein the second flow rate value corresponds to an expected average mass flow rate of a cryogen through the second needle probe during a cooling phase of a cryotherapy treatment cycle; and

determining, based on the second flow rate value, a new target heater power to be applied by the heater for a treatment cycle to be performed with the second needle probe.

16. A method for stabilizing pressure within a cryogenic device during a cryotherapy treatment, the method comprising:

receiving a first flow rate value, wherein the first flow rate value corresponds to an expected average mass flow rate of a cryogen through a first needle probe of the cryogenic device during a cryotherapy treatment cycle;

determining, based on the first flow rate value, a first target heater power to be applied to a heater associated with the cryogenic device for a first treatment cycle, wherein the heater is configured to heat the cryogen;

receiving an input for the first treatment cycle;

causing the cryogen to flow for a period of time toward the first needle probe in response to the input;

applying the first target heater power to the heater during the first treatment cycle so as to cause the heater to heat the cryogen and stabilize pressure within the cryogenic device during or after the first treatment cycle;

determining a first pressure of the cryogenic device prior to a cooling cycle of the first treatment cycle;

determining a second pressure of the cryogenic device prior to a cooling cycle of a second treatment cycle; and

calculating a second target heater power for the second treatment cycle, wherein the second target heater power is calculated at least in part by:

adjusting the first target heater power upward when the second pressure is lower than the first pressure; or

adjusting the first target heater power downward when the second pressure is greater than the first pressure.

17. A cryogenic device comprising:

a cryogen source including a pressurized cryogen;

a cryogen pathway configured to direct the cryogen toward a needle probe comprising one or more needles, wherein the cryogen is configured to deliver cryotherapy to a target tissue via the one or more needles;

a heater; and

a processor configured to:

receive a first flow rate value, wherein the first flow rate value corresponds to an expected average mass flow rate of a cryogen through a first needle probe of the cryogenic device during a cryotherapy treatment cycle;

determine, based on the first flow rate value, a first target heater power to be applied to a heater associated with the cryogenic device for a first treatment cycle, wherein the heater is configured to heat the cryogen;

receive an input for the first treatment cycle;

cause the cryogen to flow for a period of time toward the first needle probe in response to the input;

apply the first target heater power to the heater during the first treatment cycle so as to heat the cryogen and stabilize pressure within the cryogenic device during or after the first treatment cycle

receive pressure data from a pressure sensor of the cryogenic device during the first treatment cycle;

calculate, based on the received pressure data, an average rate of change in pressure during a cooling phase of the first treatment cycle; and

calculate a second target heater power for a second treatment cycle, wherein the second target heater power is calculated at least in part by adjusting the first target heater power upward or downward by an adjustment value based on the average rate of change in pressure.

18. The cryogenic device of claim 17 , wherein the first target heater power is defined such that an average rate of change in pressure during a cooling cycle of the first treatment cycle remains within a predefined range.

19. The cryogenic device of claim 17 , wherein the processor is further configured to determine that the average rate of change in pressure is negative, wherein the second target heater power is calculated at least in part by adjusting the first target heater power upward by the adjustment value.

20. The cryogenic device of claim 17 , wherein the processor is further configured to determine that the average rate of change in pressure is positive, wherein the second target heater power is calculated at least in part by adjusting the first target heater power downward by the adjustment value.