Generating artificial pulse

1. A mechanical circulatory assist system comprising:

a continuous-flow pump comprising a centrifugal rotor configured to generate a centrifugal flow, wherein the continuous-flow pump is adapted to pump blood from a left ventricle of a heart of a patient to an aorta of the patient to assist blood flow from the left ventricle to the aorta; and

a controller comprising a sensor that generates a signal indicative of a power consumption of the continuous-flow pump, wherein the controller is operatively connected to the continuous-flow pump and configured to operate the continuous-flow pump in an artificial pulse mode comprising recurring changes in a rotational speed of the continuous-flow pump, wherein at least one of the recurring changes in the rotational speed of the continuous-flow pump are synchronized with contractions of the left ventricle, wherein the controller comprising a processor configured to detect, based on a speed of the continuous-flow pump and the power consumption of the continuous-flow pump, the contractions of the left ventricle.

2. The mechanical circulatory assist system of claim 1 , wherein the continuous-flow pump comprises a stator that radially surrounds the centrifugal rotor and is operable to rotate the centrifugal rotor and radially levitate the centrifugal rotor using only passive and active magnetic forces.

3. The mechanical circulatory assist system of claim 2 , wherein the stator comprises drive coils operable to rotate the centrifugal rotor and levitation coils operable to magnetically radially levitate the centrifugal rotor.

4. The mechanical circulatory assist system of claim 3 , wherein the artificial pulse mode comprises:

(a) operating the continuous-flow pump at a first speed for a first speed duration;

(b) reducing the speed of the continuous-flow pump from the first speed to a second speed;

(c) operating the continuous-flow pump at the second speed for a second speed duration;

(d) reducing the speed of the continuous-flow pump from the second speed to a third speed;

(e) operating the continuous-flow pump at the third speed for a third speed duration; and repeating steps (a) through (e).

5. The mechanical circulatory assist system of claim 4 , wherein the controller operates the continuous-flow pump at the first speed during the contractions of the left ventricle.

6. The mechanical circulatory assist system of claim 5 , wherein the controller controls at least one of the first speed duration, the second speed duration, and the third speed duration to synchronize operation of the continuous-flow pump in the artificial pulse mode with the contractions of the left ventricle.

7. The mechanical circulatory assist system of claim 6 , wherein each of the first speed durations begins at a start of a respective contraction of the left ventricle.

8. The mechanical circulatory assist system of claim 7 , wherein each of the first speed durations ends approximately at an end of the respective contraction of the left ventricle.

9. The mechanical circulatory assist system of claim 4 , wherein the controller operates the continuous-flow pump at the first speed during relaxation of the left ventricle.

10. The mechanical circulatory assist system of claim 4 , wherein the artificial pulse mode further comprises returning the speed of the continuous-flow pump from the third speed to the first speed by overshooting the first speed to a greater speed before returning to the first speed.

11. A method of controlling a continuous-flow ventricular assist device, the method comprising:

generating, by a sensor, a signal indicative of indicative of a power consumption of a continuous-flow ventricular assist device comprising a centrifugal rotor configured to generate a centrifugal flow, wherein the continuous-flow ventricular assist device receives blood from a ventricle of a heart of a patient and pumps the blood to an aorta of the patient to assist blood flow from the ventricle to the aorta;

detecting, by a controller based on a speed of the continuous-flow ventricular assist device and the power consumption of the continuous-flow ventricular assist device, contractions of the ventricle; and

controlling, by the controller, the speed of the continuous-flow ventricular assist device to operate in an artificial pulse mode that produces a pulsatile blood flow, wherein the artificial pulse mode comprises recurring changes in a rotational speed of the continuous-flow ventricular assist device, and wherein at least one of the recurring changes in the rotational speed of the continuous-flow ventricular assist device are synchronized with the contractions of the ventricle.

12. The method of claim 11 , wherein the continuous-flow ventricular assist device comprises a stator that radially surrounds the centrifugal rotor and is operable to rotate the centrifugal rotor and radially levitate the centrifugal rotor using only passive and active magnetic forces.

13. The method of claim 12 , wherein the stator comprises drive coils operable to rotate the centrifugal rotor and levitation coils operable to magnetically radially levitate the centrifugal rotor.

14. The method of claim 11 , wherein the artificial pulse mode comprises:

(a) operating the continuous-flow ventricular assist device at a first speed for a first speed duration;

(b) reducing the speed of the continuous-flow ventricular assist device from the first speed to a second speed;

(c) operating the continuous-flow ventricular assist device at the second speed for a second speed duration;

(d) reducing the speed of the continuous-flow ventricular assist device from the second speed to a third speed;

(e) operating the continuous-flow ventricular assist device at the third speed for a third speed duration; and

repeating steps (a) through (e).

15. The method of claim 14 , wherein the controller operates the continuous-flow ventricular assist device at the first speed during the contractions of the ventricle.

16. The method of claim 15 , wherein the controller controls at least one of the first speed duration, the second speed duration, and the third speed duration to synchronize operation of the continuous-flow ventricular assist device in the artificial pulse mode with the contractions of the ventricle.

17. The method of claim 16 , wherein each of the first speed durations begins at a start of a respective contraction of the ventricle.

18. The method of claim 17 , wherein each of the first speed durations ends approximately at an end of the respective contraction of the ventricle.

19. The method of claim 14 , wherein the controller operates the continuous-flow ventricular assist device at the first speed during relaxation of the ventricle.

20. The method of claim 14 , wherein the artificial pulse mode further comprises returning the speed of the continuous-flow ventricular assist device from the third speed to the first speed by overshooting the first speed to a greater speed before returning to the first speed.

21. The mechanical circulatory assist system of claim 1 , wherein:

the continuous-flow pump comprises a housing that defines an inlet cannula, an outlet opening, and a blood flow channel that fluidly connects the outlet opening with the inlet cannula; and

the inlet cannula is configured to extend into the left ventricle.

22. The mechanical circulatory assist system of claim 4 , wherein the artificial pulse mode is configured to produce a rate of blood pressure change in a range from 500 to 1000 mmHG per second.

23. The method of claim 11 , wherein the continuous-flow ventricular assist device comprises a housing that defines an inlet cannula that extends into the ventricle.

24. The method of claim 14 , wherein a rate of blood pressure change produce by the continuous-flow ventricular assist device in the artificial pulse mode is in a range from 500 to 1000 mmHG per second.

25. A mechanical circulatory assist system comprising:

a continuous-flow pump comprising a centrifugal rotor configured to generate a centrifugal flow, wherein the continuous-flow pump is adapted to pump blood from a left ventricle of a heart of a patient to an aorta of the patient to assist blood flow from the left ventricle to the aorta; and

a controller comprising a sensor that generates a signal indicative of a power consumption of the continuous-flow pump, wherein the controller is operatively connected to the continuous-flow pump and configured to operate the continuous-flow pump in an artificial pulse mode synchronized with contractions of the left ventricle, wherein the artificial pulse mode is configured to produce a rate of blood pressure change in a range from 500 to 1000 mmHG per second, wherein the controller comprising a processor configured to detect, based on a speed of the continuous-flow pump and the power consumption of the continuous-flow pump, the contractions of the left ventricle.

26. The mechanical circulatory assist system of claim 25 , wherein the artificial pulse mode comprises recurring changes in a rotational speed of the continuous-flow pump, wherein at least one of the recurring changes in the rotational speed of the continuous-flow pump are synchronized with the contractions of the left ventricle.