IP Library Granted Patent US 11,491,336
Granted Patent B2
US 11,491,336 · App. 17/105,345 · Granted Nov 8, 2022

Neuromodulation system

Inventors: Mathieu Scheltienne (Eindhoven, NL); Jeroen Tol (Eindhoven, NL); Robin Brouns (Eindhoven, NL)
Assignee: ONWARD MEDICAL N.V.
A61N1/36192A61N1/36067A61N1/36142A61N1/36175A61N1/36178A61N1/36196
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Quick Facts
Patent No.
US 11,491,336
App. No.
17/105,345
Granted
Nov 8, 2022
Kind
B2
Abstract

A neuromodulation system including at least one input module for inputting a planned neuromodulation event or a series of neuromodulation events and at least one analyzing module for analyzing a neuromodulation event or a series of neuromodulation events. The analyzing module and the input module may be connected such that the input module is configured to forward the planned neuromodulation event or a series of neuromodulation events to the analyzing module and the analyzing module is configured to analyze the planned neuromodulation event or a series of neuromodulation events regarding one or more possible neuromodulation conflict(s).

Claims (30)

1. A neuromodulation system comprising:

at least one input module for inputting a planned neuromodulation event or a series of neuromodulation events of at least one stimulation block;

wherein the stimulation block comprises at least one electrode of an electrode array; and

wherein the stimulation block is activated to elicit or facilitate the movement of a patient; and

at least one analyzing module for analyzing a neuromodulation event or a series of neuromodulation events;

wherein the analyzing module and the input module are connected such that the input module is configured to forward the planned neuromodulation event or series of neuromodulation events to the analyzing module; and

wherein the analyzing module is configured to analyze the planned neuromodulation event or a series of neuromodulation events for one or more possible neuromodulation conflict(s).

2. The neuromodulation system according to claim 1 , wherein the one or more possible neuromodulation conflict(s) is/are related to at least one of neuromodulation safety, hardware capabilities, software capabilities.

3. The neuromodulation system according to claim 2 , wherein the conflict is incompatible electrode configuration between stimulation blocks, incompatible timing of stimulation blocks, or incompatible amplitude properties of the stimulation blocks.

4. The neurostimulation system according to claim 1 , wherein the neuromodulation system further comprises at least one correction module which is configured to amend the planned neuromodulation event or series of neuromodulation events such that in case of detection of a neurostimulation conflict the neuromodulation event or series of neuromodulation events is/are amended such that the neuromodulation conflict is corrected.

5. The neurostimulation system according to claim 1 , wherein the neuromodulation system further comprises output means, wherein the output means are connected to the analyzing module and is configured to provide at least partially a visual output of at least one of the analysis performed by an analysis module, the planned neuromodulation event or a series of neuromodulation events, the neuromodulation conflict(s), and the correction of the planned neuromodulation event or a series of neuromodulation events.

6. The neuromodulation system according to claim 1 , wherein a conflict is an impossible electrode configuration.

7. The neuromodulation system according to claim 4 , wherein the neuromodulation system is configured for a semi-automatic or automatic correction of the neuromodulation conflict.

8. The neuromodulation system according to claim 7 , wherein the correction is selected from merging, interleaving pulses, amending VRAM available, amending computation time, replacing the planned neuromodulation event or series of neuromodulation events with one of an alternative preset, allowing some pulse overlap, or amending the timing properties.

9. The neuromodulation system according to claim 8 , wherein the timing properties are frequency, pulse width, and pulse shape.

10. A method for performing neuromodulation, the method comprising at least the following steps:

analyzing a neuromodulation event or a series of neuromodulation events of at least one stimulation block;

wherein the stimulation block comprises at least one electrode of an electrode array; and

wherein the stimulation block is activated to elicit or facilitate movement of a patient;

wherein the analyzing includes the analysis whether the planned neuromodulation event or a series of neuromodulation events comprises one or more possible neuromodulation conflict(s) between at least two stimulation blocks.

11. The method of claim 10 , wherein the one or more possible neuromodulation conflict(s) is/are related to at least one of neuromodulation safety, hardware capabilities, software capabilities.

12. The method of claim 11 , wherein the conflict is incompatible electrode configuration between stimulation blocks, incompatible stimulation block timing, or incompatible stimulation block amplitude properties.

13. The method of claim 10 , wherein the method further comprises the step of correcting the neuromodulation event or a series of neuromodulation events such that the one or more possible neuromodulation conflict(s) is/are avoided.

14. The method of claim 13 , wherein the correction is automatic, semi-automatic, or manual.

15. The method according to claim 13 , wherein the correction is selected from merging, interleaving pulses, amending VRAM available, amending computation time, replacing the planned neuromodulation event or series of neuromodulation events with one of an alternative preset, allowing some pulse overlap, or amending the timing properties.

16. The method according to claim 15 , wherein the timing properties are frequency, pulse width, and pulse shape.

17. The method according to claim 16 , wherein the pulse shape is amended by shortening biphasic pulses in a post-stimulation phase.

18. The method according to claim 15 , wherein merging is selected when a frequency of the stimulation blocks in conflict is within 15 Hz.

19. The method according to claim 15 , wherein merging is selected when an amplitude of the stimulation blocks in conflict is within 2 mA.

20. The method according to claim 10 , wherein when a conflict is identified, the method computes a pulse distance matrix of the at least two stimulation blocks and when a timing between the at least two stimulation blocks is below a threshold, the amplitude of electrodes used by the stimulation blocks is lowered.

Assignments (6)
SECURITY INTEREST Recorded Aug 14, 2024
From: ONWARD MEDICAL N.V.
To: RUNWAY GROWTH FINANCE CORP., AS COLLATERAL AGENT
Reel/Frame 068287/0393 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE TYPOGRAPHICAL ERROR THAT LISTED APPLICTION NO. 29/782, 452 INSTEAD OF APPLICATION NO. 29782,453 PREVIOUSLY RECORDED AT REEL: 058600 FRAME: 0518. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Mar 1, 2022
From: ONWARD MEDICAL B.V.
To: ONWARD MEDICAL N.V.
Reel/Frame 059280/0326 →
CHANGE OF NAME Recorded Dec 28, 2021
From: ONWARD MEDICAL B.V.
To: ONWARD MEDICAL N.V.
Reel/Frame 058600/0518 →
MERGER AND CHANGE OF NAME Recorded Feb 11, 2021
From: GTX MEDICAL B.V.; ONWARD MEDICAL B.V.
To: ONWARD MEDICAL B.V.
Reel/Frame 056282/0119 →
CHANGE OF NAME Recorded Feb 5, 2021
From: GTX MEDICAL B.V.
To: ONWARD MEDICAL B.V.
Reel/Frame 055236/0263 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 25, 2020
From: SCHELTIENNE, MATHIEU; TOL, JEROEN; BROUNS, ROBIN
To: GTX MEDICAL B.V.
Reel/Frame 055027/0052 →
Priority Claims (1)
EP 19211738 · Nov 27, 2019 · regional
Continuity (1)
Related Publication 20210154481A1 · May 27, 2021
Cited By (5)
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