IP Library Granted Patent US 11,139,063
Granted Patent B1
US 11,139,063 · App. 17/136,126 · Granted Oct 5, 2021

Systems and methods for generating a microbiome balance plan for prevention of bacterial infection

Inventor: Kenneth Neumann (Lakewood, CO)
Assignee: KPN INNOVATIONS, LLC.
G16H20/60G06N20/00G16H10/60G16H50/20G16H50/70G16H70/60
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Quick Facts
Patent No.
US 11,139,063
App. No.
17/136,126
Granted
Oct 5, 2021
Kind
B1
Abstract

A system for generating a microbiome balance plan including a computing device configured to receive at least a microbe indicator, retrieve a microbiome profile, assign the microbiome profile to a microbe category, determine, using the microbe category and the microbiome profile, a microbe reduction strategy, determining at least a first nutrient amount that aids in reduction of at least a first microbe, identify a first nutrition element, wherein the first nutrition element contains at least a first nutrient amount, determine, using the microbe category and the microbiome profile, a microbiome supplementation program, identifying at least a second microbe to be included to the microbiome profile, determining at least a second nutrition element that aids in supplementation of the at least a second microbe, identify a second plurality of nutrition elements, generate a microbiome balance plan, using the microbe reduction strategy and the microbiome supplementation program.

Claims (86)

1. A system for generating a microbiome balance plan for prevention of bacterial infection, the system comprising a computing device, wherein the computing device is configured to:

receive at least a microbe indicator, wherein a microbe indicator is a biomarker that originates from a user;

retrieve a microbiome profile related to the user, wherein retrieving the microbiome profile further comprises:

training a microbiome profile machine-learning model with training data wherein the training data includes a plurality of data entries correlating a plurality of microbe indicators to a plurality of microorganisms; and

generating the microbiome profile as a function of the training data and the microbiome profile machine-learning model;

assign the microbiome profile to a microbe category;

determine, using the microbe category and the microbiome profile, a microbe reduction strategy, wherein determining the microbe reduction strategy includes:

locating at least a first microbe to be reduced from the microbiome profile;

identifying at least a first nutrient amount that aids in reduction of the at least a first microbe; and

determining at least a first nutrition element, wherein the at least a first nutrition element includes the at least a first nutrient;

identify, using the microbe category and the microbiome profile, a microbiome supplementation program, wherein determining the microbiome supplementation program includes:

locating at least a second microbe to be included to the microbiome profile;

determining at least a second nutrient amount that aids in supplementation to microbiome profile of the at least a second microbe; and

identifying at least a second nutrition element, wherein of the at least a second nutrition element includes the at least a second nutrient amount; and

generate a microbiome balance plan, using the microbe reduction strategy and the microbiome supplementation program, wherein the microbiome balance plan includes a frequency of the at least a first nutrient element, a magnitude of the at least a first nutrient element, a frequency of the at least a second nutrient element, and a magnitude of the at least a second nutrient element; and

display the microbiome balance plan to the user.

2. The system of claim 1 , wherein assigning the microbiome profile to a microbe category further comprises:

training a microbiome classifier using a microbiome classification machine-learning process and training data including a plurality of data entries correlating microbiome profile data to subsets of categorized users;

classifying the microbiome profile to the microbe category using the microbiome classifier; and

assigning the microbe category as a function of the classifying.

3. The system of claim 1 , wherein identifying the at least a first microbe further comprises generating a pathogen index, wherein generating the pathogen index includes:

training a pathogenicity machine-learning model using a pathogenicity machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to indexing values for identifying pathogenic microbes; and

assigning the pathogen index to each element in the microbiome profile of the user according to the pathogen index and the pathogenicity machine-learning model.

4. The system of claim 3 , wherein identifying the at least a first microbe further comprises:

generating a pathogenic microbiome standard, wherein generating the pathogenic microbiome standard further comprises training a pathogenicity classifier using a pathogenicity classification machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to microbe categories based on pathogenicity;

determining a pathogenicity threshold from the pathogenic microbiome standard;

comparing the microbiome profile of the user to the pathogenicity threshold; and

identifying the at least a first microbe as a function of the comparison.

5. The system of 1 , determining the at least a first nutrient amount that aids in reduction of the at least a first microbe further comprises:

training a reduction model using a reduction machine-learning process and training data, wherein training data includes a plurality of data entries of nutrition amounts correlated to reducing microbial populations; and

determining the at least a first nutrient amount as a function of the at least a first microbe and the reduction model.

6. The system of claim 1 , wherein identifying at least a second microbe further comprises generating a balancing index, wherein generating the balancing index includes:

training a microbe balancing machine-learning model using a microbe balancing machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to indexing values for identifying beneficial microbes; and

assigning the balancing index to each element in the microbiome profile of the user according to the balancing index and the microbe balancing machine-learning model.

7. The system of claim 6 , wherein identifying the at least a second microbe further comprises:

generating a balancing standard, wherein generating the balancing standard further comprises training a microbe balancing classifier using a balancing classification machine-learning process and training data which includes a plurality of data entries of microbiome profile data from subsets of users correlated to microbe categories based on incidence of microbes;

determining a balancing threshold from the balancing standard;

comparing the microbiome profile of the user to the balancing standard; and

identifying the at least a second microbe as a function of the comparison.

8. The system of 1 , determining the at least a second nutrient amount that aids in supplementation of the at least a second microbe further comprises:

training a supplementation model using a supplementation machine-learning process and training data, wherein training data includes a plurality of data entries of nutrition amounts correlated to increasing microbial populations; and

determining the at least a second nutrient amount as a function of the at least a second microbe and the supplementation model.

9. The system of claim 1 , wherein generating the microbiome balance plan further comprises generating an objective function with the at least a first nutrition element and the at least a second nutrition element wherein the objection function outputs at least an ordering of a nutrition element according to constraints from the microbe reduction strategy and the microbiome supplementation program.

10. A method for generating a microbiome balance plan for prevention of bacterial infection, the method comprising:

receiving, by a computing device, at least a microbe indicator, wherein a microbe indicator is a biomarker that originates from a user;

retrieving, by the computing device, a microbiome profile related to the user, wherein retrieving the microbiome profile further comprises:

training a microbiome profile machine-learning model with training data wherein the training data includes a plurality of data entries correlating a plurality of microbe indicators to a plurality of microorganisms; and

generating the microbiome profile as a function of the training data and the microbiome profile machine-learning model;

assigning, by the computing device, the microbiome profile to a microbe category;

determining, by the computing device, using the microbe category and the microbiome profile, a microbe reduction strategy, wherein determining the microbe reduction strategy includes:

locating at least a first microbe to be reduced from the microbiome profile;

identifying at least a first nutrient amount that aids in reduction of the at least a first microbe; and

determining at least a first nutrition element, wherein the at least a first nutrition element includes the at least a first nutrient;

identifying, by the computing device, using the microbe category and the microbiome profile, a microbiome supplementation program, wherein determining the microbiome supplementation program includes:

locating at least a second microbe to be included to the microbiome profile;

determining at least a second nutrient amount that aids in supplementation to microbiome profile of the at least a second microbe; and

identifying at least a second nutrition element, wherein of the at least a second nutrition element includes the at least a second nutrient amount; and

generating, by the computing device, a microbiome balance plan, using the microbe reduction strategy, and the microbiome supplementation program, wherein the microbiome balance plan includes a frequency and a magnitude of the at least a first nutrient element, and a frequency and a magnitude of the at least a second nutrient element; and

displaying, by the computing device, the microbiome balance plan to the user.

11. The method of claim 10 , wherein assigning the microbiome profile to a microbe category further comprises:

training a microbiome classifier using a microbiome classification machine-learning process and training data including a plurality of data entries correlating microbiome profile data to subsets of categorized users;

classifying the microbiome profile to the microbe category using the microbiome classifier; and

assigning the microbe category as a function of the classifying.

12. The method of claim 10 , wherein identifying the at least a first microbe further comprises generating a pathogen index, wherein generating the pathogen index includes:

training a pathogenicity machine-learning model using a pathogenicity machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to indexing values for identifying pathogenic microbes; and

assigning the pathogen index to each element in the microbiome profile of the user according to the pathogen index and the pathogenicity machine-learning model.

13. The method of claim 12 , wherein identifying the at least a first microbe further comprises:

generating a pathogenic microbiome standard, wherein generating the pathogenic microbiome standard further comprises training a pathogenicity classifier using a pathogenicity classification machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to microbe categories based on pathogenicity;

determining a pathogenicity threshold from the pathogenic microbiome standard;

comparing the microbiome profile of the user to the pathogenicity threshold; and

identifying the at least a first microbe as a function of the comparison.

14. The method of 10 , determining the at least a first nutrient amount that aids in reduction of the at least a first microbe further comprises:

training a reduction model using a reduction machine-learning process and training data, wherein training data includes a plurality of data entries of nutrition amounts correlated to reducing microbial populations; and

determining the at least a first nutrient amount as a function of the at least a first microbe and the reduction model.

15. The method of claim 10 , wherein identifying at least a second microbe further comprises generating a balancing index, wherein generating the balancing index includes:

training a microbe balancing machine-learning model using a microbe balancing machine-learning process and training data including a plurality of data entries of microbiome profile data from subsets of users correlated to indexing values for identifying beneficial microbes; and

assigning the balancing index to each element in the microbiome profile of the user according to the balancing index and the microbe balancing machine-learning model.

16. The method of claim 15 , wherein identifying the at least a second microbe further comprises:

generating a balancing standard, wherein generating the balancing standard further comprises training a microbe balancing classifier using a balancing classification machine-learning process and training data which includes a plurality of data entries of microbiome profile data from subsets of users correlated to microbe categories based on incidence of microbes;

determining a balancing threshold from the balancing standard;

comparing the microbiome profile of the user to the balancing standard; and

identifying the at least a second microbe as a function of the comparison.

17. The method of 10 , determining the at least a second nutrient amount that aids in supplementation of the at least a second microbe further comprises:

training a supplementation model using a supplementation machine-learning process and training data, wherein training data includes a plurality of data entries of nutrition amounts correlated to increasing microbial populations; and

determining the at least a second nutrient amount as a function of the at least a second microbe and the supplementation model.

18. The method of claim 10 , wherein generating the microbiome balance plan further comprises generating an objective function with the at least a first nutrition element and the at least a second nutrition element wherein the objection function outputs at least an ordering of a nutrition element according to constraints from the microbe reduction strategy and the microbiome supplementation program.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2021
From: NEUMANN, KENNETH
To: KPN INNOVATIONS, LLC.
Reel/Frame 055482/0883 →
Cited By (2)
US 12,417,836 US 12,494,289