IP Library Granted Patent US 12,213,485
Granted Patent B2
US 12,213,485 · App. 17/146,662 · Granted Feb 4, 2025

Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops

Inventors: Rodrigo Cifuentes (Santiago, CL); Daniel MacLean (Geneva, NY); Renee Engle-Goodner (Sacramento, CA); Timothy Malefyt (Stroudsburg, PA)
Assignee: AGROFRESH INC.
A01N55/08A01N25/12A01N59/02A01N59/04
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Quick Facts
Patent No.
US 12,213,485
App. No.
17/146,662
Granted
Feb 4, 2025
Kind
B2
Abstract

The present disclosure relates to methods for using benzoxaborole compounds in combination with preservative gases, such as carbon dioxide or sulfur dioxide, as an antimicrobial that synergistically controls pathogens of agricultural crops.

Claims (16)

1. A method of treating plants with an antimicrobial agent comprising:

placing one or more plants or plant parts in a chamber,

adding a benzoxaborole compound and SO 2 to the chamber,

wherein the benzoxaborole compound and the SO 2 combine to form the antimicrobial treatment, and

contacting the one or more plants or plant parts with the antimicrobial treatment, wherein the benzoxaborole compound is

wherein the SO 2 concentration is about 0.001% to about 1%, and

wherein the benzoxaborole is applied at a concertation from about 0.0088 mg/L to about 0.035 mg/L.

2. The method of claim 1 , wherein the one or more plants or plant parts is a soft fruit.

3. The method of claim 2 , wherein the soft fruit is selected from the group consisting of a strawberry, a raspberry, a blackberry, a blueberry, and a grape.

4. The method of claim 1 , wherein the SO 2 concentration is about 0.01% to about 0.05%.

5. The method of claim 1 , wherein the benzoxaborole compound is in the form of a liquid, a gas, a fog, or a solid.

6. The method of claim 1 , wherein the benzoxaborole compound is in the form of a powder.

7. The method of claim 1 , wherein the antimicrobial treatment is in the form of a spray, a mist, a gel, a thermal fog, a non-thermal fog, a drench, a vapor, a gas, or sublimation.

8. The method of claim 1 , wherein the antimicrobial treatment further comprises a treatment carrier.

9. The method of claim 1 , wherein the antimicrobial treatment is effective against fungal pathogens selected from the group consisting of Acremonium spp., Albugo spp., Alternaria spp., Ascochyta spp., Aspergillus spp., Botryodiplodia spp., Botryospheria spp., Botrytis spp., Byssochlamys spp., Candida spp., Cephalosporium spp., Ceratocystis spp., Cercospora spp., Chalara spp., Cladosporium spp., Colletotrichum spp., Cryptosporiopsis spp., Cylindrocarpon spp., Debaryomyces spp., Diaporthe spp., Didymella spp., Diplodia spp., Dothiorella spp., Elsinoe spp., Fusarium spp., Geotrichum spp., Gloeosporium spp., Glomerella spp., Helminthosporium spp., Khuskia spp., Lasiodiplodia spp., Macrophoma spp., Macrophomina spp., Microdochium spp., Monilinia spp., Monilochaethes spp., Mucor spp., Mycocentrospora spp., Mycosphaerella spp., Nectria spp., Neofabraea spp., Nigrospora spp., Penicillium spp., Peronophythora spp., Peronospora spp., Pestalotiopsis spp., Pezicula spp., Phacidiopycnis spp., Phoma spp., Phomopsis spp., Phyllosticta spp., Phytophthora spp., Polyscytalum spp., Pseudocercospora spp., Pyricularia spp., Pythium spp., Rhizoctonia spp., Rhizopus spp., Sclerotium spp., Sclerotinia spp., Septoria spp., Sphaceloma spp., Sphaeropsis spp., Stemphyllium spp., Stilbella spp., Thielaviopsis spp., Thyronectria spp., Trachysphaera spp., Uromyces spp., Ustilago spp., Venturia spp., and Verticillium spp., and bacterial pathogens, such as Bacillus spp., Campylobacter spp., Clavibacter spp., Clostridium spp., Erwinia spp., Escherichia spp., Lactobacillus spp., Leuconostoc spp., Listeria spp., Pantoea spp., Pectobacterium spp., Pseudomonas spp., Ralstonia spp., Salmonella spp., Shigella spp., Staphylococcus spp., Vibrio spp., Xanthomonas spp., and Yersinia spp.

10. The method of claim 1 , wherein the SO2 concentration is about 0.1% to about 1%.

Assignments (2)
AGREEMENT OF AGENT RESIGNATION, APPOINTMENT AND ACCEPTANCE & MASTER ASSIGNMENT OF SECURITY DOCUMENTS Recorded Jun 24, 2024
From: JPMORGAN CHASE BANK, N.A.
To: ALTER DOMUS US LLC
Reel/Frame 067914/0941 →
SECURITY INTEREST Recorded Mar 31, 2023
From: AGROFRESH INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 063214/0683 →
Continuity (3)
Continuation 15452499 · Mar 7, 2017
Provisional Application 62304636 · Mar 7, 2016
Related Publication 20210137121A1 · May 13, 2021
References Cited (4)
US 20130298290A1 · Haas · 2013 [cited by examiner]
US 20140349853A1 · Maclean · 2014 [cited by examiner]
US 20160324160A1 · Benkovic · 2016 [cited by examiner]
Dauthy (Fruit and Vegetable Processing: Chapter 5.3 Chemical Preservation FAO) (Year: 1995). [cited by examiner]