IP Library › Patent Application 17153494
Patent Application
App. No. 17/153,494

METHODS OF TREATING HYPERTRIGLYCERIDEMIA

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Quick Facts
Patent No.
US None
App. No.
17/153,494
Abstract

In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.

Claims (5)

1 . A method of lowering high-sensitivity C-reactive protein in a subject in need thereof, the method comprising:

determining a baseline high-sensitivity C-reactive protein level in the subject, the subject having a triglyceride level of at least 500 mg/dl; and

administering to the subject daily (a) about 4 g of a pharmaceutical composition comprising at least 96% pure ethyl-EPA and (b) a statin for a period of at least 12 weeks to effect a reduction in high-sensitivity C-reactive protein of at least about 20% compared to the baseline.

2 . The method of claim 1 wherein the pharmaceutical composition contains substantially no DHA or derivative thereof.

3 . The method of claim 1 wherein the subject has a triglyceride level of 500 mg/dl to about 2000 mg/dl.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 9, 2021
From: MANKU, MEHAR; OSTERLOH, IAN; WICKER, PIERRE; BRAECKMAN, RENE; SONI, PARESH; AMARIN PHARMA, INC.
To: AMARIN PHARMA, INC.; AMARIN PHARMACEUTICALS IRELAND LIMITED
Reel/Frame 055879/0750 →