IP Library Granted Patent US 11,839,744
Granted Patent B2
US 11,839,744 · App. 17/179,070 · Granted Dec 12, 2023

Automated super bolus generation

Inventors: Benyamin Grosman (Winnetka, CA); Louis J. Lintereur (Boise, ID); Anirban Roy (Agoura Hills, CA); Neha J. Parikh (West Hills, CA); Di Wu (Glendale, CA); Patrick E. Weydt (Moorpark, CA); David Dunleavy (West Hills, CA); Ali Dianaty (Porter Ranch, CA)
Assignee: Medtronic MiniMed, Inc.
A61M5/1723A61M2205/52A61M2230/201
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Quick Facts
Patent No.
US 11,839,744
App. No.
17/179,070
Granted
Dec 12, 2023
Kind
B2
Abstract

Techniques related to automatically generating a super bolus may include determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal. The amount of the augmented meal bolus may exceed a sufficient amount for counteracting a glucose level increase caused by the meal. In some embodiments, the techniques may further include determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced. In some other embodiments, the techniques may further include delivering the augmented meal bolus to the patient prior to determining whether or not to cause reduction of basal dosage deliveries. More specifically, a glucose level of the patient may be obtained after delivery of the augmented meal bolus, and the obtained glucose level may be used to determine whether to reduce basal dosage deliveries.

Claims (63)

1. A system for automatically generating a super bolus, the system comprising:

one or more processors; and

one or more processor-readable storage media storing instructions which, when executed by the one or more processors, cause performance of:

determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal, the amount of the augmented meal bolus exceeding a sufficient amount for counteracting a glucose level increase caused by the meal;

determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced; and

after determining the amount of the augmented meal bolus and the duration of the postprandial reduction period, causing:

delivery of the augmented meal bolus to the patient in the determined amount, and

reduction of basal dosage deliveries to the patient for the duration of the postprandial reduction period.

2. The system of claim 1 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on the excess amount, a number of basal dosage deliveries to forgo.

3. The system of claim 1 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on an active insulin time, an amount of time for metabolizing the excess amount.

4. The system of claim 1 , wherein determining the amount of the augmented meal bolus comprises:

obtaining an amount of carbohydrates included in the meal; and

multiplying an adjusted insulin-to-carbohydrate ratio to the amount of carbohydrates included in the meal.

5. The system of claim 1 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on:

determining an average rate of basal dosage deliveries during a historical time period; and

multiplying the average rate of basal dosage deliveries to a predetermined duration.

6. The system of claim 1 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on determining a total amount of basal dosage deliveries during a historical time period.

7. The system of claim 1 , wherein the one or more processor-readable storage media further store instructions which, when executed by the one or more processors, cause performance of:

prior to determining the amount of the augmented meal bolus, detecting occurrence of the meal.

8. A processor-implemented method for automatically generating a super bolus, the method comprising:

determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal, the amount of the augmented meal bolus exceeding a sufficient amount for counteracting a glucose level increase caused by the meal;

determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced; and

after determining the amount of the augmented meal bolus and the duration of the postprandial reduction period, causing:

delivery of the augmented meal bolus to the patient in the determined amount, and

reduction of basal dosage deliveries to the patient for the duration of the postprandial reduction period.

9. The method of claim 8 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on the excess amount, a number of basal dosage deliveries to forgo.

10. The method of claim 8 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on an active insulin time, an amount of time for metabolizing the excess amount.

11. The method of claim 8 , wherein determining the amount of the augmented meal bolus comprises:

obtaining an amount of carbohydrates included in the meal; and

multiplying an adjusted insulin-to-carbohydrate ratio to the amount of carbohydrates included in the meal.

12. The method of claim 8 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on:

determining an average rate of basal dosage deliveries during a historical time period; and

multiplying the average rate of basal dosage deliveries to a predetermined duration.

13. The method of claim 8 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on determining a total amount of basal dosage deliveries during a historical time period.

14. The method of claim 8 , further comprising:

prior to determining the amount of the augmented meal bolus, detecting occurrence of the meal.

15. One or more non-transitory processor-readable storage media storing instructions which, when executed by one or more processors, cause performance of:

determining an amount of an augmented meal bolus to be delivered to a patient for regulating the patient's glycemic response to a meal, the amount of the augmented meal bolus exceeding a sufficient amount for counteracting a glucose level increase caused by the meal;

determining a duration of a postprandial reduction period during which basal dosage deliveries to the patient are to be reduced; and

after determining the amount of the augmented meal bolus and the duration of the postprandial reduction period, causing:

delivery of the augmented meal bolus to the patient in the determined amount, and

reduction of basal dosage deliveries to the patient for the duration of the postprandial reduction period.

16. The one or more non-transitory processor-readable storage media of claim 15 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on the excess amount, a number of basal dosage deliveries to forgo.

17. The one or more non-transitory processor-readable storage media of claim 15 , wherein determining the duration of the postprandial reduction period comprises:

calculating an excess amount by which the amount of the augmented meal bolus exceeds the sufficient amount; and

calculating, based on an active insulin time, an amount of time for metabolizing the excess amount.

18. The one or more non-transitory processor-readable storage media of claim 15 , wherein determining the amount of the augmented meal bolus comprises:

obtaining an amount of carbohydrates included in the meal; and

multiplying an adjusted insulin-to-carbohydrate ratio to the amount of carbohydrates included in the meal.

19. The one or more non-transitory processor-readable storage media of claim 15 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on:

determining an average rate of basal dosage deliveries during a historical time period; and

multiplying the average rate of basal dosage deliveries to a predetermined duration.

20. The one or more non-transitory processor-readable storage media of claim 15 , wherein determining the amount of the augmented meal bolus comprises calculating an excess amount to be added to the sufficient amount based on determining a total amount of basal dosage deliveries during a historical time period.

Assignments (2)
SECURITY INTEREST Recorded Jan 16, 2026
From: MEDTRONIC MINIMED, INC.; COMPANION MEDICAL, INC.
To: CITIBANK, N.A.
Reel/Frame 074394/0237 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2021
From: GROSMAN, BENYAMIN; LINTEREUR, LOUIS J.; ROY, ANIRBAN; PARIKH, NEHA J.; WU, DI; WEYDT, PATRICK E.; DUNLEAVY, DAVID; DIANATY, ALI
To: MEDTRONIC MINIMED, INC.
Reel/Frame 055323/0554 →
Continuity (1)
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