WATER-SOLUBLE FORMULATIONS, METHODS OF MAKING AND USE
Water-soluble formulations including cannabinoids or a cannabis -derived compound for use in beverages and foods, methods of preparing the formulations, and methods of preparing beverages and foods including the formulations are disclosed herein. In some embodiments, the water-soluble formulations comprise a cannabinoid or a cannabis -derived compound; an emulsifier comprising Quillaja saponins; a carrier oil, and a glycerin-based carrier surfactant.
1 . A water-soluble formulation comprising a cannabinoid or a cannabis -derived compound; an emulsifier comprising Quillaja saponins; a carrier oil, and a glycerin-based carrier surfactant.
2 . The water-soluble formulation of claim 1 , wherein the emulsifier comprising Quillaja saponins is a Q-NATURALE® emulsifier, Saponin from Quillaja Bark, Saponin Quillaja sp., a Quillaja extract, purified Quillaja saponins, or any combination thereof.
3 . The water-soluble formulation of claim 2 , wherein the emulsifier comprising Quillaja saponins is a Q-NATURALE® emulsifier.
4 . The water-soluble formulation of claim 1 , wherein the carrier oil is comprised of monoglycerides or medium chain triglycerides.
5 . The water-soluble formulation of claim 4 , wherein the carrier oil is comprised of monoglycerides, and the monoglycerides comprise glyceryl monostearate, glyceryl hydroxystearate, glyceryl monoleate, winterized glyceryl monoleate, monolaurin, glyceryl monolinoleate, or any combination thereof.
6 . The water-soluble formulation of claim 1 , which comprises up to 10% by weight of the cannabinoid or cannabis -derived compound, up to 15% by weight of the emulsifier comprising Quillaja saponins, and up to 10% by weight of the carrier oil.
7 . The water-soluble formulation of claim 1 , which comprises a ratio of glycerin-based carrier surfactant:emulsifier comprising Quillaja saponins of between about 25:1 and about 5:1.
8 . The water-soluble formulation of claim 1 , which comprises a ratio of glycerin-based carrier surfactant:carrier oil of between about 75:1 and about 25:1.
9 . The water-soluble formulation of claim 1 , wherein the cannabinoid is cannabinoid is THC (Δ9-THC), Δ8-THC, trans-Δ10-THC, cis-Δ10-THC, THCA, THCV, Δ8-THCA, Δ9-THCA, Δ8-THCV, Δ9-THCV, THCVA, CBD, CBDA, CBDV, CBDVA, CBC, CBCA, CBCV, CBCVA, CBG, CBGA, CBGV, CBGVA, CBN, CBNA, CBNV, CBNVA, CBND, CBNDA, CBNDV, CBNDVA, CBE, CBEA, CBEV, CBEVA, CBL, CBLA, CBLV, CBLVA, CBT, cannabicitran, or any combination thereof.
10 . The water-soluble formulation of claim 1 , wherein the cannabinoid is THC.
11 . The water-soluble formulation of claim 1 , wherein the cannabinoid is CBD.
12 . The water-soluble formulation of claim 1 , wherein the glycerin-based carrier surfactant is a vegetable glycerin.
13 . The water-soluble formulation of claim 1 , which comprises between about 60% and about 97% by weight of the glycerin-based carrier surfactant.
14 . The water-soluble formulation of claim 1 , further comprising one or more additives selected from the group consisting of terpenes, terpenoids, flavonoids, viscosity modifiers, natural emulsifiers, oils, thickening agents, minerals, acids, bases, vitamins, flavours, colourants, sweeteners, and combinations thereof.
15 . A beverage comprising the water-soluble formulation of claim 1 .
16 . The beverage of claim 15 , which comprises one or more salts.
17 . The beverage of claim 16 , which is a sports drink beverage.
18 . The beverage of claim 17 , which comprises between about 0.1% and about 25% by weight of the water-soluble formulation.
19 . The beverage of claim 18 , which comprises between about 0.01 mg/mL and about 2.5 mg/mL of CBD.
20 . The beverage of claim 17 , which is in Tetra Pak™ 0 packaging.
21 . A method for preparing the water-soluble formulation of claim 1 , the method comprising:
mixing a cannabinoid or a cannabis -derived compound with a carrier oil to provide a cannabinoid mixture;
mixing a glycerin-based carrier surfactant and an emulsifier comprising Quillaja saponins to provide a glycerin-based mixture; and
combining the cannabinoid mixture and the glycerin-based mixture under high shear homogenization to prepare the water-soluble formulation.
22 . The method according to claim 21 , wherein the emulsifier comprising Quillaja saponins is a Q-NATURALS® emulsifier, Saponin from Quillaja Bark, Saponin Quillaja sp., a Quillaja extract, purified Quillaja saponins, or any combination thereof.
23 . The method according to claim 21 , wherein the emulsifier comprising Quillaja saponins is a Q-NATURALS® emulsifier.
24 . The method according to claim 21 , wherein the cannabinoid is CBD.
25 . The method according to claim 21 , wherein the cannabinoid is THC.