Zirconium oxide module conditioning
The invention relates to devices, systems, and methods for conditioning a zirconium oxide sorbent module for use in dialysis after recharging. The devices, systems, and methods can provide for conditioning and recharging of zirconium oxide in a single system, or in separate systems.
1. A method of conditioning zirconium oxide, comprising the steps of:
pumping a conditioning solution through a zirconium oxide sorbent module in a flow path; and
conditioning the zirconium oxide sorbent module using the conditioning solution comprising sodium bicarbonate at a desired zirconium oxide effluent pH.
2. The method of claim 1 , further comprising the step of pumping a base solution through the zirconium oxide sorbent module to recharge zirconium oxide in the zirconium oxide sorbent module prior to conditioning the zirconium oxide sorbent module.
3. The method of claim 2 , wherein the base solution is a sodium hydroxide solution.
4. The method of claim 1 , further comprising the step of pumping the conditioning solution through a zirconium phosphate sorbent module prior to pumping the conditioning solution through the zirconium oxide sorbent module.
5. The method of claim 4 , wherein the flow path is a dialysate flow path comprising the zirconium phosphate sorbent module and zirconium oxide sorbent module.
6. The method of claim 4 , wherein the flow path is a recharging flow path comprising the zirconium phosphate sorbent module and zirconium oxide sorbent module.
7. The method of claim 6 , wherein the recharging flow path is in a recharger.
8. The method of claim 1 , wherein the desired zirconium oxide effluent pH is between 5 and 7.5.
9. The method of claim 1 , further comprising the step of generating the conditioning solution in the flow path.
10. The method of claim 9 , wherein the step of generating the conditioning solution comprises mixing a sodium bicarbonate solution with acid.
11. The method of claim 9 , wherein the step of generating the conditioning solution comprises mixing a sodium bicarbonate solution with carbon dioxide.
12. The method of claim 1 , wherein the conditioning solution is pumped through the zirconium oxide sorbent module for between 5-30 minutes.
13. The method of claim 1 , further comprising the step of disinfecting the zirconium oxide sorbent module by pumping a disinfectant solution through the zirconium oxide sorbent module.
14. The method of claim 9 , wherein the step of generating the conditioning solution comprises pumping a fluid in a dialysate flow path through a first sorbent module; the first sorbent module containing solid sodium bicarbonate.
15. The method of claim 10 , wherein the sodium bicarbonate solution and acid are mixed in a static mixer.
16. The method of claim 13 , wherein the disinfectant solution comprises at least one of bleach, peracetic acid, and/or citric acid.
17. The method of claim 11 , wherein the step of mixing sodium bicarbonate solution with carbon dioxide comprises metering carbon dioxide gas into a bicarbonate source.
18. The method of claim 17 , further comprising the step of monitoring a pH of the bicarbonate solution while metering the carbon dioxide gas into the bicarbonate source.
19. The method of claim 1 , wherein the conditioning solution further comprises a disinfectant.
20. The method of claim 19 , wherein the disinfectant is bleach.