Medical plug delivery devices with a rotatable magazine and related components and methods

1. A delivery device for delivering compositions or medical articles to a patient, the delivery device comprising:

a rotatable magazine defining:

a central lumen that extends through the rotatable magazine; and

a plurality of chambers disposed around the central lumen;

a frame comprising a proximal channel, a distal channel, and a connecting region disposed between the proximal channel and the distal channel; and

an elongate shaft that both extends through the central lumen of the rotatable magazine and is coupled to the frame;

wherein rotation of the rotatable magazine about the elongate shaft causes the delivery device to transition from a first configuration in which a first chamber of the plurality of chambers is aligned with both the proximal channel and the distal channel to a second configuration in which a second chamber of the plurality of chambers is aligned with both the proximal channel and the distal channel; and

wherein each chamber of the plurality of chambers includes a primary channel and a bypass channel, wherein the bypass channel provides a fluid flow path around the primary channel.

2. The delivery device of claim 1 , wherein the distal channel and the proximal channel are co-linear with one another, but are not co-linear with the connecting region.

3. The delivery device of claim 1 , wherein the frame provides a compressive force for facilitating a fluid-tight seal between the frame and a chamber of the plurality of chambers of the rotatable magazine.

4. The delivery device of claim 1 , wherein a first end of the elongate shaft is attached to the frame, and a second end of the elongate shaft that is disposed opposite the first end is not attached to the frame.

5. The delivery device of claim 4 , wherein the frame comprises a cavity for receiving the second end of the elongate shaft, wherein the cavity is elongate in shape to permit deflection of the frame as the delivery device transitions from the first configuration to the second configuration.

6. The delivery device of claim 1 , wherein the frame comprises at least one notch that creates a flex point on the frame.

7. The delivery device of claim 1 , wherein the rotatable magazine further comprises a third chamber.

8. The delivery device of claim 1 , further comprising a syringe that is configured to couple to a proximal adaptor of the frame.

9. The delivery device of claim 1 , wherein interaction between the rotatable magazine and the frame provides audible and/or tactile feedback to indicate that one of the plurality of chambers is aligned with both the proximal channel and the distal channel of the frame.

10. The delivery device of claim 1 , wherein the rotatable magazine is rotatable about the elongate shaft in only a single direction.

11. The delivery device of claim 10 , further comprising a stop that is configured to prevent more than one rotation of the rotatable magazine about the elongate shaft.

12. The delivery device of claim 1 , wherein the frame comprises a first hub with a first plurality of spokes extending therefrom and a second hub with a second plurality of spokes extending therefrom, wherein each spoke is coupled to a cap that is configured to interact with a chamber to prevent a composition from escaping from the chamber.

13. The delivery device of claim 1 , wherein the delivery device is structured to:

maintain a medical plug within the chamber when a proximally directed flow of fluid passes through the chamber; and

permit deployment of the medical plug when a distally directed flow of fluid passes through the chamber.

14. The delivery device of claim 1 , further comprising a cartridge disposed within each chamber of the plurality of chambers, wherein each cartridge defines a shoulder adjacent a proximal end of the cartridge, the shoulder being configured to engage a medical plug and restrict movement of the medical plug proximal of the shoulder.

15. The delivery device of claim 1 , further comprising a plurality of medical plugs, wherein one medical plug of the plurality of medical plugs is disposed within each chamber of the rotatable magazine.

16. The delivery device of claim 1 , wherein each chamber of the plurality of chambers is preloaded with a medicament.

17. A medical plug delivery assembly comprising:

a fluid delivery device;

a frame configured for coupling to a distal end of the fluid delivery device, the frame comprising a distal channel; and

a rotatable magazine defining a plurality of chambers, wherein each chamber of the plurality of chambers is configured to receive a medical plug;

wherein the rotatable magazine is disposed between a distal portion of the frame and a proximal portion of the frame that together provide a compressive force on the rotatable magazine to form a fluid-tight seal between the frame and a chamber of the plurality of chambers of the rotatable magazine; and

wherein rotational displacement of the rotatable magazine with respect to the frame transitions the assembly from a first configuration in which a first chamber of the plurality of chambers is in fluid communication with the distal channel of the frame to a second configuration in which a second chamber of the plurality of chambers is in fluid communication with the distal channel of the frame; and

wherein each chamber of the plurality of chambers includes a primary channel and a bypass channel, wherein the bypass channel provides a fluid flow path around the primary channel.

18. The medical plug delivery assembly of claim 17 , wherein each chamber of the plurality of chambers is configured to maintain a medical plug within the chamber when a proximally directed flow of fluid passes through the chamber and wherein the medical plug is deployed through the distal channel of the frame when a distally directed flow of fluid passes through the chamber.