Biological Fluid Filtration System
A biological fluid filtration system for scanning a biological fluid so as to filter potentially undesirable constituents from the biological fluid for therapeutic or diagnostic purposes. The biological fluid filtration system generally includes a fluid receiving device adapted to receive a biological fluid. A valve including an inlet, a first outlet, and a second outlet is fluidly connected to the fluid receiving device. The biological fluid within the fluid receiving device is scanned by a scanner to produce scanned data relating to the biological fluid. A control unit in communication with the scanner and the valve receives the scanned data and controls the valve based on the scanned data. The valve is controlled to direct the biological fluid through either the first or second outlet of the valve depending upon the constituents of the biological fluid identified by the control unit.
1 . A portable biological fluid filtration system, comprising:
a housing including an inlet and an outlet, wherein the inlet of the housing is adapted to receive a biological fluid from a patient;
a fluid filtration device including an inlet, a first outlet, and a second outlet, wherein the inlet of the fluid filtration device is fluidly connected to the inlet of the housing, wherein the fluid filtration device is adapted to receive the biological fluid, and wherein the second outlet of the fluid filtration device is fluidly connected to the outlet of the housing;
wherein the fluid filtration device is configured to separate a first subset of constituents and a second subset of constituents from the biological fluid, wherein the first subset of constituents includes an undesirable constituent, wherein the second subset of constituents does not include the undesirable constituent, wherein the fluid filtration device is configured to direct the first subset of constituents through the first outlet of the fluid filtration device, and wherein the fluid filtration device is configured to direct the second subset of constituents through the second outlet of the fluid filtration device; and
a cartridge removably attached to the housing, wherein the cartridge is fluidly connected to the first outlet of the fluid filtration device, wherein the cartridge is adapted to receive the first subset of constituents.
2 . The portable biological fluid filtration system of claim 1 , further comprising a return channel fluidly connected between the outlet of the housing and a source of the biological fluid.
3 . The portable biological fluid filtration system of claim 1 , wherein the fluid filtration device includes a valve, wherein the valve is comprised of an inlet, a first outlet, and a second outlet, wherein the inlet of the valve is fluidly connected to the inlet of the fluid filtration device, wherein the first outlet of the valve is fluidly connected to the first outlet of the fluid filtration device, and wherein the second outlet of the valve is fluidly connected to the second outlet of the fluid filtration device.
4 . The portable biological fluid filtration system of claim 3 , wherein the fluid filtration device includes a scanner configured to scan the biological fluid within the fluid filtration device to produce a scanned data relating to the biological fluid within the fluid filtration device.
5 . The portable biological fluid filtration system of claim 4 , wherein the fluid filtration device includes a control unit in communication with the scanner and the valve, wherein the control unit is configured to receive the scanned data from the scanner, and wherein the control unit is configured to control the valve based on the scanned data from the scanner.
6 . The portable biological fluid filtration system of claim 1 , wherein the fluid filtration device includes an anti-coagulant insert, wherein the anti-coagulant insert is configured to apply an anti-coagulant to the biological fluid within the fluid filtration device.
7 . The portable biological fluid filtration system of claim 1 , wherein the fluid filtration device includes a power source.
8 . The portable biological fluid filtration system of claim 1 , wherein the housing includes at least one indicator adapted to convey an operational status of the fluid filtration device.
9 . The portable biological fluid filtration system of claim 1 , wherein the fluid filtration device includes a buffer fluid insert, wherein the buffer fluid insert is adapted to apply a buffer fluid to the biological fluid within the fluid filtration device.
10 . The portable biological fluid filtration system of claim 1 , wherein the housing includes a presorting device fluidly connected between the inlet of the housing and the inlet of the fluid filtration device.
11 . The portable biological fluid filtration system of claim 10 , wherein the presorting device is comprised of a centrifuge.
12 . The portable biological fluid filtration system of claim 10 , wherein the presorting device is adapted to apply a chemical agent to the biological fluid.
13 . The portable biological fluid filtration system of claim 12 , wherein the chemical agent is comprised of a red blood cell lysis buffer.
14 . The portable biological fluid filtration system of claim 10 , wherein the presorting device is comprised of a microfluidic separation device.
15 . The portable biological fluid filtration system of claim 14 , wherein the microfluidic separation device is adapted to apply inertial focusing to the biological fluid.
16 . The portable biological fluid filtration system of claim 1 , further comprising a drug infuser device fluidly connected between the second outlet of the fluid filtration device and the outlet of the housing.
17 . The portable biological fluid filtration system of claim 1 , further comprising a catheter including an inlet port and an outlet port, wherein the inlet port of the catheter is fluidly connected to the inlet of the housing, and wherein the outlet port of the catheter is fluidly connected to the outlet of the housing.
18 . A method of filtering a biological fluid using the portable biological fluid filtration system of claim 1 , comprising the steps of:
receiving the biological fluid by the fluid filtration device;
separating the first subset of constituents from the second subset of constituents by the fluid filtration device;
directing the first subset of constituents into the cartridge; and
directing the second subset of constituents through the outlet of the housing.
19 . The portable biological fluid filtration system of claim 1 , wherein the housing is adapted to be worn on a body of a patient.
20 . A portable biological fluid filtration system, comprising:
a housing including an inlet and an outlet, wherein the inlet of the housing is adapted to receive a biological fluid from a patient, wherein the housing is adapted to be worn on a body of a patient;
a fluid filtration device including an inlet, a first outlet, and a second outlet, wherein the inlet of the fluid filtration device is fluidly connected to the inlet of the housing, wherein the fluid filtration device is adapted to receive the biological fluid, and wherein the second outlet of the fluid filtration device is fluidly connected to the outlet of the housing;
wherein the fluid filtration device is configured to separate a first subset of constituents and a second subset of constituents from the biological fluid, wherein the first subset of constituents includes an undesirable constituent, wherein the second subset of constituents does not include the undesirable constituent, wherein the fluid filtration device is configured to direct the first subset of constituents through the first outlet of the fluid filtration device, and wherein the fluid filtration device is configured to direct the second subset of constituents through the second outlet of the fluid filtration device;
wherein the fluid filtration device includes a valve, wherein the valve is comprised of an inlet, a first outlet, and a second outlet, wherein the inlet of the valve is fluidly connected to the inlet of the fluid filtration device, wherein the first outlet of the valve is fluidly connected to the first outlet of the fluid filtration device, and wherein the second outlet of the valve is fluidly connected to the second outlet of the fluid filtration device;
wherein the fluid filtration device includes a scanner configured to scan the biological fluid within the fluid filtration device to produce a scanned data relating to the biological fluid within the fluid filtration device;
wherein the fluid filtration device includes a control unit in communication with the scanner and the valve, wherein the control unit is configured to receive the scanned data from the scanner, and wherein the control unit is configured to control the valve based on the scanned data from the scanner; and
a cartridge removably attached to the housing, wherein the cartridge is fluidly connected to the first outlet of the fluid filtration device, wherein the cartridge is adapted to receive the first subset of constituents.