IP Library Patent Application 17210351
Patent Application
App. No. 17/210,351

GRADIENT WAVEFORM DESIGN FOR LOW-FIELD MAGNETIC RESONANCE IMAGING SYSTEMS

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Quick Facts
Patent No.
US None
App. No.
17/210,351
Abstract

Systems and methods for generating a gradient waveform for use by a low-field MRI system to generate a gradient magnetic field are provided herein. The gradient waveform can be determined using first information indicative of the gradient waveform and second information indicative of hardware constraints of the low-field MRI system including a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil. In some embodiments, the gradient waveform can be a trapezoidal gradient waveform determined to have a non-linear ramp-up portion and/or a non-linear ramp-down portion.

Claims (43)

1 . A method of generating a gradient waveform for use by a low-field magnetic resonance imaging (MRI) system to generate a gradient magnetic field, the low-field MRI system comprising a gradient coil and a gradient power amplifier for driving the gradient coil, the method comprising:

accessing first information indicative of the gradient waveform;

accessing second information indicative of hardware constraints of the low-field MRI system, the second information including one of:

(i) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil, or

(ii) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, and a voltage induced in the gradient coil in response to an applied current,

determining the gradient waveform using the first information and the second information; and

generating the gradient waveform.

2 . The method of claim 1 , further comprising:

generating the gradient magnetic field by using the gradient power amplifier and the gradient waveform to drive the gradient coil.

3 . The method of claim 1 , wherein determining the gradient waveform is performed using a ratio of the resistance of the gradient coil and the inductance of the gradient coil.

4 . The method of claim 1 , wherein determining the gradient waveform comprises determining gradient waveform parameters subject to hardware constraints specified using a differential equation, the differential equation specified in part using the second information.

5 . The method of claim 1 , wherein accessing the first information comprises accessing information including a moment of the gradient magnetic field, a duration of the gradient magnetic field, and/or a maximum value of the gradient magnetic field.

6 . The method of claim 1 , wherein accessing the first information comprises accessing a pre-determined gradient waveform.

7 . The method of claim 1 , further comprising:

after determining the gradient waveform, rotating a frame of reference of the gradient waveform to match a frame of reference of the low-field MRI system.

8 . The method of claim 1 , wherein the gradient waveform is a trapezoidal gradient waveform having a ramp-up portion, a top portion, and a ramp-down portion.

9 . The method of claim 8 , wherein determining the gradient waveform comprises determining a shape of the ramp-up portion and/or the ramp-down portion using the first information and the second information.

10 . The method of claim 1 , wherein the maximum slew rate has a magnitude in a range from 10 T/m/s to 80 T/m/s.

11 . The method of claim 1 , wherein the maximum slew rate has a magnitude in a range from 25 T/m/s to 65 T/m/s.

12 . The method of claim 1 , wherein the maximum voltage of the gradient power amplifier has a magnitude in a range from 20 V to 120 V.

13 . The method of claim 1 , wherein the maximum voltage of the gradient power amplifier has a magnitude in a range from 40 V to 60 V.

14 . The method of claim 1 , wherein the low-field MRI system further comprises at least one permanent magnet configured to generate a B 0 magnetic field having a strength less than 0.2 T.

15 . The method of claim 1 , wherein the low-field MRI system further comprises at least one permanent magnet configured to generate a B 0 magnetic field having a strength in a range from 50 mT to 0.1 T.

16 . At least one non-transitory computer-readable storage medium storing processor-executable instructions that, when executed by a low-field magnetic resonance imaging (MRI) system, cause the low-field MRI system to perform a method of generating a gradient waveform for use by the low-field MRI system to generate a gradient magnetic field, the low-field MRI system comprising a gradient coil and a gradient power amplifier for driving the gradient coil, the method comprising:

accessing first information indicative of the gradient waveform;

accessing second information indicative of hardware constraints of the low-field MRI system, the second information including one of:

(i) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil, or

(ii) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, and a voltage induced in the gradient coil in response to an applied current,

determining the gradient waveform using the first information and the second information; and

generating the gradient waveform.

17 . A low-field magnetic resonance imaging (MRI) system, comprising:

a magnetics system comprising a plurality of magnetics components configured to produce magnetic fields for performing magnetic resonance imaging, the plurality of magnetics components comprising a gradient coil and a gradient power amplifier for driving the gradient coil; and

at least one controller configured to operate one or more of the plurality of magnetics components, wherein the at least one controller is configured to:

access first information indicative of a gradient waveform;

access second information indicative of hardware constraints of the low-field MRI system, the second information including one of:

(i) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, a resistance of the gradient coil, and an inductance of the gradient coil, or

(ii) information indicative of a maximum voltage of the gradient power amplifier, a maximum slew rate of the gradient coil, and a voltage induced in the gradient coil in response to an applied current,

determine the gradient waveform using the first information and the second information; and

generate the gradient waveform.

18 . The low-field MRI system of claim 17 , wherein the at least one controller is further configured to:

generate a gradient magnetic field by using the gradient power amplifier and the gradient waveform to drive the gradient coil.

19 . The low-field MRI system of claim 17 , wherein the at least one controller is further configured to determine the gradient waveform by using a ratio of the resistance of the gradient coil and the inductance of the gradient coil.

20 . The low-field MRI system of claim 17 , wherein the at least one controller is further configured to determine the gradient waveform by determining gradient waveform parameters subject to hardware constraints specified using a differential equation, the differential equation specified in part using the second information.

Assignments (3)
CHANGE OF NAME Recorded Mar 7, 2022
From: HYPERFINE, INC.
To: HYPERFINE OPERATIONS, INC.
Reel/Frame 059332/0615 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 28, 2021
From: DYVORNE, HADRIEN A.; SACOLICK, LAURA; O'HALLORAN, RAFAEL; LAZARUS, CAROLE; TWIEG, MICHAEL
To: HYPERFINE RESEARCH, INC.
Reel/Frame 056690/0873 →
CHANGE OF NAME Recorded Jun 28, 2021
From: HYPERFINE RESEARCH, INC.
To: HYPERFINE, INC.
Reel/Frame 056699/0226 →