Compressible adjuncts with drug release features

1. A compressible adjunct for use with a staple cartridge, the compressible adjunct comprising:

a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer and configured to be releasably retained on a staple cartridge and configured to be delivered to tissue by deployment of staples in the cartridge, the adjunct material comprising a lattice macrostructure having a plurality of drug delivery microstructures formed in the lattice macrostructure, each drug delivery microstructure having drug disposed therein, wherein the plurality of drug delivery microstructures are configured to encapsulate the drug to thereby prevent drug release until the plurality of drug delivery microstructures are at least one of thermally ruptured while the adjunct material is stapled to tissue and mechanically ruptured in response to at least one of clamping, stapling, and cutting of the adjunct material

wherein the lattice macrostructure includes a plurality of hollow tubes that extend between and connect adjacent drug delivery microstructures to each other such that the plurality of drug delivery microstructures are in fluid communication with each other at least prior to thermal rupture or mechanical rupture.

2. The adjunct of claim 1 , the plurality of drug delivery microstructures are configured to thermally rupture in response to an increase in temperature.

3. The adjunct of claim 2 , wherein the increase in temperature is in response to an infection of the tissue that is stapled to the adjunct material.

4. The adjunct of claim 1 , wherein the plurality of drug delivery microstructures are configured to thermally rupture when the adjunct material is at or above an activation temperature.

5. The adjunct of claim 1 , wherein the plurality of drug delivery microstructures comprise at least one triply periodic minimal surface structure.

6. The adjunct of claim 1 , wherein the plurality of drug delivery microstructures comprise at least one Schwarz-P structure.

7. The adjunct of claim 1 , wherein at least a portion of the hollow tubes have drug disposed therein.

8. A stapling assembly for use with a surgical stapler, the stapling assembly comprises:

a cartridge having a plurality of staples disposed therein, the plurality of staples being configured to be deployed into tissue; and

a non-fibrous adjunct formed of at least one fused bioabsorbable polymer and configured to be releasably retained on the cartridge such that the adjunct can be attached to tissue by the plurality of staples in the cartridge, the adjunct comprises a lattice main structure having a plurality of first microreservoirs formed therein, each first microreservoir having drug disposed therein, and a plurality of hollow connecting structures that extend between and connect adjacent first microreservoirs of the plurality of first microreservoirs to each other such that a continuous network of pathways between the plurality of first microreservoirs are present within the adjunct,

wherein the plurality of first microreservoirs are each configured to release corresponding drug therefrom in response to at least one of clamping, stapling, and cutting of the adjunct.

9. The staple assembly of claim 8 , wherein the plurality of first microreservoirs are positioned within regions of the adjunct that overlap with staple legs of the plurality of staples when the adjunct is releasably retained on the cartridge, and wherein the staple legs are configured to advance through the plurality of first microreservoirs and release drug therefrom and into tissue as the plurality of staples are deployed into tissue.

10. The staple assembly of claim 8 , wherein the cartridge includes a slot that is defined therein and configured to receive a cutting element, and wherein the plurality of first microreservoirs are positioned within regions of the adjunct that overlap with the slot when the adjunct is releasably retained on the cartridge, and wherein the cutting element is configured to sever the plurality of first microreservoirs to cause drug to release therefrom as the cutting element advances through the slot.

11. The stapling assembly of claim 8 , wherein the lattice main structure comprises a plurality of triply periodic minimal surface structures, and wherein each triply periodic minimal surface structure defines a respective first microreservoir of the plurality of first microreservoirs.

12. The stapling assembly of claim 11 , wherein the plurality of triply periodic minimal surface structures comprise at least one Schwarz-P structure.

13. The stapling assembly of claim 8 , wherein at least a portion of the plurality of hollow connecting structures have drug disposed therein.

14. The stapling assembly of claim 8 , wherein the lattice main structure comprises a plurality of second microreservoirs, each second microreservoir having drug disposed therein.

15. The stapling assembly of claim 14 , wherein the cartridge includes a slot that is defined therein and configured to receive a cutting element, and wherein the plurality of second microreservoirs are positioned within regions of the adjunct that overlap with the slot when the adjunct is releasably retained on the cartridge, and wherein the cutting element is configured to sever the plurality of second microreservoirs to cause drug to release therefrom as the cutting element advances through the slot.

16. The stapling assembly of claim 14 , wherein the lattice main structure comprises a plurality of Schwarz-P structures, and wherein at least one of the plurality of first microreservoirs and the plurality of second microreservoirs is defined by the plurality of Schwarz-P structures.