IP Library Granted Patent US 11,627,961
Granted Patent B2
US 11,627,961 · App. 17/216,994 · Granted Apr 18, 2023

Compressible adjuncts with different behavioral zones

Inventors: Frederick E. Shelton, IV (Hillsboro, OH); Jason L. Harris (Lebanon, OH); Michael J. Vendely (Lebanon, OH); Christopher Q. Seow (Cincinnati, OH)
A61B17/0686A61B17/07292A61B2017/00004A61B2017/00893A61B2017/07257A61B2017/07271
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Quick Facts
Patent No.
US 11,627,961
App. No.
17/216,994
Granted
Apr 18, 2023
Kind
B2
Abstract

Compressible adjuncts for use with a staple cartridge are provided. In one exemplary embodiment, the compressible adjunct includes a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer. The adjunct material is configured to be releasably retained on a staple cartridge and is configured to be delivered to tissue by deployment of staples in the cartridge The adjunct material includes a lattice macrostructure having at least one drug contained therein. The lattice macrostructure is formed of a plurality of unit cells, in which each unit cell is configured to eject a predetermined amount of drug from the adjunct material and the predetermined amount of the drug being a function of a compression profile of the respective unit cell.

Claims (24)

1. A compressible adjunct for use with a staple cartridge, the compressible adjunct comprising:

a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer and configured to be releasably retained on a staple cartridge and configured to be delivered to tissue by deployment of staples in the cartridge, the adjunct material comprising a lattice macrostructure having at least one drug contained therein, the lattice macrostructure being formed of a plurality of unit cells, wherein each unit cell is configured to eject a predetermined amount of drug from the adjunct material and the predetermined amount of the drug being a function of a compression profile of the respective unit cell;

wherein the plurality of unit cells include first unit cells having a first compression profile and second unit cells having a second compression profile that is different than the first compression profile.

2. The adjunct of claim 1 , wherein each unit cell comprises a plurality of compression zones.

3. The adjunct of claim 2 , wherein the plurality of compression zones comprise a first compression zone having a first compressive strength and a second compression zone having a second compressive strength that is different than the first compressive strength.

4. The adjunct of claim 3 , wherein the first compression zone is configured to compress from a first uncompressed height to a first compressed height, and wherein the second compression zone is configured to compress from a second uncompressed height to a second compressed height that is different than the first compressed height.

5. The adjunct of claim 1 , wherein the plurality of unit cells comprise Schwarz-P structures.

6. The adjunct of claim 5 , wherein the lattice macrostructure comprises a plurality of connecting structures that extend between and connect adjacent Schwarz-P structures to each other.

7. The adjunct of claim 1 , wherein at least one unit cell of the plurality of unit cells has a variable wall thickness.

8. A compressible adjunct for use with a staple cartridge, the compressible adjunct comprising:

a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer and configured to be releasably retained on a staple cartridge and configured to be delivered to tissue by deployment of staples in the cartridge, the adjunct material comprising a lattice macrostructure having at least one drug contained therein, the lattice macrostructure being formed of a plurality of unit cells, wherein each unit cell is configured to eject a predetermined amount of drug from the adjunct material and the predetermined amount of the drug being a function of a compression profile of the respective unit cell;

wherein each unit cell includes a plurality of sub-structures formed therein and configured to control the deformation behavior of the respective unit cell when the adjunct material is being compressed.

9. The adjunct of claim 8 , wherein the plurality of sub-structures comprise first sub-structures and second sub-structures, wherein the first sub-structures are projections that extend inward from a wall of the unit cell and the second sub-structures are recesses formed in a wall of the unit cell.

10. The adjunct of claim 8 , wherein the plurality of sub-structures comprise at least one internal stopping member.

11. A compressible adjunct for use with a staple cartridge, the compressible adjunct comprising:

a non-fibrous adjunct material formed of at least one fused bioabsorbable polymer and configured to be releasably retained on a staple cartridge and configured to be delivered to tissue by deployment of staples in the cartridge, the adjunct material comprising a lattice main structure having at least one drug contained therein, the lattice main structure comprising first sub-structures formed in at least one first portion of the lattice main structure and second sub-structures formed in at least one second portion of the lattice main structure, wherein the first sub-structures and the second sub-structures are configured to control a first release rate and a second release rate, respectively, of the at least one drug from the adjunct material when the adjunct material is compressed and in a tissue deployed state, the first release rate being different than the second release rate.

12. The adjunct of claim 11 , wherein the first portion of the lattice main structure has a first wall thickness and the second portion of the lattice main structure has a second wall thickness that is different than the first wall thickness.

13. The adjunct of claim 11 , wherein the first portion of the lattice main structure is configured to deform from a first undeformed state to a first deformed state.

14. The adjunct of claim 13 , wherein the second portion of the lattice main structure is configured to deform from a second undeformed state to a second deformed state that is different than the first deformed state.

15. The adjunct of claim 11 , wherein the first sub-structures comprises at least one of a first projection that extends inward from a wall of the lattice main structure and a first recess formed in a wall of the lattice main structure.

16. The adjunct of claim 11 , wherein the second sub-structures comprises at least one of a second projection that extends inward from a wall of the lattice main structure and a second recess formed in a wall of the lattice main structure.

17. The adjunct of claim 11 , wherein at least one of the first sub-structures and the second sub-structures comprise at least one internal stopping member.

18. The adjunct of claim 11 , wherein the lattice main structure comprises a plurality of Schwarz-P structures.

19. The adjunct of claim 18 , wherein the lattice main structure comprises a plurality of connecting structures that extend between and connect adjacent Schwarz-P structures to each other.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 8, 2021
From: SHELTON, FREDERICK E., IV; HARRIS, JASON L.; VENDELY, MICHAEL J.; SEOW, CHRISTOPHER Q.
To: CILAG GMBH INTERNATIONAL
Reel/Frame 056794/0148 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 6, 2021
From: ETHICON LLC
To: CILAG GMBH INTERNATIONAL
Reel/Frame 056983/0569 →
Cited By (1)
US 12,446,874