Treatment of infections and biofilm formation using a cellulose synthase inhibitor
In one embodiment, the present application relates to methods and materials for weed control of a field of a crop plant using a cellulose biosynthesis inhibitor selected from the group consisting of ES20 and ES20-1 to ES20-9 of FIG. 1 A. In another embodiment, the present disclosure relates to a method for treatment or prevention of an infection through inhibition of biofilm formation of microorganisms comprising the step of applying a therapeutic effective amount of a cellulose biosynthesis inhibitor selected from the group consisting of ES20 and ES20-1˜ES20-9 of FIG. 1 A, or a salt thereof, in combination with one or more other commonly used antibiotics. A composition matter comprising said compounds and methods of use are within the scope of the present invention.
1. A method of weed control for a field of a plant comprising the step of applying a cellulose biosynthesis inhibitor selected from the group consisting of
or a salt thereof, in combination with isoxaben, together with one or more diluents, to a field in need of said weed control.
2. The method of claim 1 , wherein said cellulose biosynthesis inhibitor and other herbicides are applied to a field of a plant together as a mixture of preformulated single product.
3. The method of claim 1 , wherein said cellulose biosynthesis inhibitor and other herbicides are applied to a field of a plant separately as an individually pre-formulated product, consequentially or concurrently.
4. The method of claim 1 , wherein said plant is resistant to said cellulose biosynthesis inhibitor
or a salt thereof.
5. The method of claim 1 , wherein said plant is a crop for food or feed.