Manufacturing of semi-plastic pharmaceutical dosage units

1. A soft chewable veterinary pharmaceutical product for oral administration,

wherein the soft chewable veterinary pharmaceutical product is obtainable by a process wherein the soft chewable veterinary pharmaceutical product is formed with a rotary moulding machine, comprising the steps of:

a) mixing at least one active pharmaceutical ingredient with one or more components wherein the components are dry components and liquid components to prepare a premix,

b) heating a polyethylene glycol forming agent until melting,

c) mixing the premix and the polyethylene glycol forming agent together to form a dough,

d) feeding the dough into a container connected with a rotary moulding machine; and

e) forming a soft chewable veterinary pharmaceutical product for oral administration in a rotary moulding machine,

wherein the liquid component comprises one or more oils and the polyethylene glycol forming agent is solid at room temperature and has a melting point between 45° C. and 100° C.;

wherein the temperature of the dough in step d) is between 35° C. and 45° C.; and

wherein the rotary moulding machine does not have a knockoff mechanism or a punch mechanism;

wherein the active pharmaceutical ingredient is 4-[5-(3,5-Dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methyl-N-[(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-benzamide; and

wherein the soft chewable veterinary pharmaceutical product has concave edges and has a weight of about 2 g or less or has a weight of more than about 10 g.

2. The soft chewable veterinary pharmaceutical product for oral administration according to claim 1 , wherein soft chewable veterinary pharmaceutical product is of cylindrical form.

3. A method of controlling a parasitic insect, acarid or nematode infestation of an animal comprising administering to the animal an effective amount of the soft chewable veterinary pharmaceutical product for oral administration of claim 1 .