IP Library › Granted Patent US 12,350,153
Granted Patent B2
US 12,350,153 · App. 17/227,749 · Granted Jul 8, 2025

Systems and methods for transcatheter treatment of valve regurgitation

Inventors: Alexander K. Khairkhahan (Palo Alto, CA); Michael D. Lesh (Mill Valley, CA); Alan R. Klenk (San Jose, CA)
Assignee: Polares Medical Inc.
A61F2/2442A61B17/0401A61F2/2454A61F2/2463A61F2/2466A61B2017/00243A61B2017/0414A61B2017/0441A61B2017/0649A61F2/2412A61F2210/0014A61F2220/0008
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Quick Facts
Patent No.
US 12,350,153
App. No.
17/227,749
Granted
Jul 8, 2025
Kind
B2
Abstract

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance devices for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, and one or more of the following: transseptal sheath, anchor delivery catheter, implant delivery catheter, and clip delivery catheter; and methods for transcatheter implantation of a coaptation element across a heart valve.

Claims (26)

1. An implant for treating mal-coaptation of a heart valve, the heart valve having an annulus and posterior and anterior leaflets with an open configuration and a closed configuration, the implant comprising:

a coaptation assist body comprising a superior edge, an inferior edge, and lateral edges that bound a first surface and a second surface, the first surface configured to be disposed toward the posterior leaflet, the second surface configured to be disposed toward the anterior leaflet to allow the anterior leaflet to coapt with the coaptation assist body,

the coaptation assist body comprising a central orifice spaced inward from the superior edge, the inferior edge, and the lateral edges, the coaptation assist body comprising lateral orifices spaced laterally from the central orifice, the coaptation assist body surrounding the central orifice and lateral orifices,

a plurality of ribbons, the plurality of ribbons comprising at least one curve, the plurality of ribbons movable from a first compressed configuration to a second expanded configuration;

an atrial anchor comprising a helical body configured to extend through the central orifice and wherein the atrial anchor is configured to rotate into the annulus; and

lateral anchors, each lateral anchor comprising a helical body configured to extend through a lateral orifice of the lateral orifices,

wherein the lateral anchors are configured to rotate into the annulus, wherein the atrial anchor and the lateral anchors provide the only fixation to the annulus.

2. The implant of claim 1 , wherein at least one ribbon of the plurality of ribbons comprise two discrete curves.

3. The implant of claim 1 , wherein the plurality of ribbons are configured to rest against the tissue of a heart.

4. The implant of claim 1 , wherein the plurality of ribbons resist movement of the coaptation assist body without penetrating a myocardium.

5. The implant of claim 1 , wherein the plurality of ribbons comprise a nickel and titanium alloy.

6. The implant of claim 1 , wherein the atrial anchor comprises an outer diameter between 1 mm and 6 mm.

7. The implant of claim 1 , wherein the atrial anchor comprises a pitch of 0.4 mm to 1.5 mm.

8. The implant of claim 1 , wherein the atrial anchor comprises a wire.

9. The implant of claim 8 , wherein the wire comprises a diameter of 0.25 mm to 0.75 mm.

10. The implant of claim 1 , wherein the atrial anchor comprises a drive continuation extending proximally from the helical body.

11. An implant for treating mal-coaptation of a heart valve, comprising:

an implant body configured to improve function of the heart valve, the implant body comprising a superior edge, an inferior edge, and lateral edges that bound a first surface and a second surface, the first surface configured to be disposed toward a posterior leaflet and the second surface configured to be disposed toward an anterior leaflet,

the implant body comprising a discrete central opening spaced inward from the superior edge, the inferior edge, and the lateral edges, the implant body comprising discrete lateral openings spaced apart from the discrete central opening;

a plurality of ribbons, the plurality of ribbons comprising a shape memory material comprising at least one curve, the plurality of ribbons movable from a first compressed configuration to a second expanded configuration;

an atrial anchor comprising a helical body, wherein the atrial anchor is configured to be rotated relative to the discrete opening to be driven into tissue of an annulus; and

lateral anchors, each lateral anchor comprising a helical body, wherein each lateral anchor is configured to be rotated relative to a discrete lateral opening of the lateral openings to be driven into tissue of the annulus, wherein the implant does not attach to an anterior aspect of the annulus and only attaches to a posterior aspect of the annulus with the atrial anchor and the lateral anchors.

12. The implant of claim 11 , wherein the implant body is configured to traverse a mitral valve.

13. The implant of claim 11 , wherein the implant body is configured to attach to a site in a left ventricle.

14. The implant of claim 11 , wherein the second surface comprises a coaptation surface for the anterior leaflet to coapt against.

15. The implant of claim 11 , wherein the implant body effectively seals off or replaces the posterior leaflet.

Assignments (2)
CHANGE OF NAME Recorded Jul 31, 2023
From: MIDDLE PEAK MEDICAL INC.
To: POLARES MEDICAL INC.
Reel/Frame 064445/0351 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 17, 2021
From: KHAIRKHAHAN, ALEXANDER K.; LESH, MICHAEL D.; KLENK, ALAN R.
To: MIDDLE PEAK MEDICAL, INC.
Reel/Frame 056580/0822 →
Continuity (4)
Continuation 16220322 · Dec 14, 2018
Continuation 14313975 · Jun 24, 2014
Provisional Application 61895647 · Oct 25, 2013
Related Publication 20210298901A1 · Sep 30, 2021
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