Compounds and methods for treating viral infections
Provided herein are methods of treating, managing and/or preventing viral infections. A particular method comprises administering to a subject in need thereof an effective amount of an adaptor associated kinase 1 inhibitor of Formula (I):
1. A method of treating or managing a SARS-CoV-2-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine:
or a pharmaceutically acceptable salt thereof.
2. A method of treating or managing a CoV-229E-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine:
or a pharmaceutically acceptable salt thereof.
3. A method of treating or managing a CoV-OC43-like coronavirus infection, the method comprising administering to a subject in need thereof a therapeutically effective amount of a compound, wherein the compound is (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan amine:
or a pharmaceutically acceptable salt thereof.