IP Library Granted Patent US 11,839,430
Granted Patent B2
US 11,839,430 · App. 17/249,026 · Granted Dec 12, 2023

Optical coherence tomography-based ophthalmic testing methods, devices and systems

Inventors: Alexander C. Walsh (Los Angeles, CA); Paul G. Updike (Cerritos, CA); Srinivas R. Sadda (Pasadena, CA)
Assignee: Doheny Eye Institute
A61B3/102A61B3/0025A61B3/0033A61B3/0041A61B3/0091A61B3/028A61B3/085A61B3/113A61B3/117A61B3/18A61B5/0066A61B5/0073
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Quick Facts
Patent No.
US 11,839,430
App. No.
17/249,026
Granted
Dec 12, 2023
Kind
B2
Abstract

In accordance with one aspect of the present invention, an optical coherence tomography-based ophthalmic testing center system includes an optical coherence tomography instrument comprising an eyepiece for receiving at least one eye of a user or subject; a light source that outputs light that is directed through the eyepiece into the user's or subject's eye, an interferometer configured to produce optical interference using light reflected from the user's/subject's eye, an optical detector disposed so as to detect said optical interference; and a processing unit coupled to the detector. The ophthalmic testing center system can be configured to perform a multitude of self-administered functional and/or structural ophthalmic tests and output the test data.

Claims (44)

1. An optical coherence tomography instrument comprising:

an eyepiece for receiving at least one eye of a user;

at least one target display visible through said eyepiece;

a light source that outputs light that is directed through the eyepiece to the at least one eye of the user;

an interferometer configured to produce optical interference using light reflected from the at least one eye of the user;

an optical detector disposed so as to detect said optical interference; and

electronics coupled to the at least one target display and said optical detector and configured to provide an output based on optical coherence tomography measurements obtained using said interferometer,

wherein said electronics are further configured to monitor a gaze of the user by tracking detectable structures of the at least one eye and conduct an extraocular motility test based on the gaze of the user, and

wherein said electronics are further configured to combine measurements from the extraocular motility test to deduce potential underlying cranial nerve palsies.

2. The optical coherence tomography instrument of claim 1 , wherein the electronics are further configured to enable the user to self-administer the extraocular motility test.

3. The optical coherence tomography instrument of claim 1 , wherein the electronics are further configured to conduct the extraocular motility test on two eyes simultaneously.

4. The optical coherence tomography instrument of claim 1 , wherein the electronics are further configured to conduct the extraocular motility test on one eye of the user and then on the other eye of the user.

5. The optical coherence tomography instrument of claim 1 , wherein the at least one target display is configured to display fixation targets configured to move to predetermined positions to test extraocular motility.

6. The optical coherence tomography instrument of claim 5 , wherein the optical coherence tomography instrument is configured to instruct the user to follow the fixation targets throughout the extraocular motility test.

7. The optical coherence tomography instrument of claim 1 , wherein the electronics are further configured to compare data from the extraocular motility test to a database to determine patterns of deviation.

8. The optical coherence tomography instrument of claim 1 , wherein the optical coherence tomography instrument is further configured to output results of the extraocular motility test.

9. The optical coherence tomography instrument of claim 1 , wherein the extraocular motility test comprises measuring an extent of movement of the at least one eye in various directions of gaze.

10. An optical coherence tomography instrument comprising:

an eyepiece for receiving at least one eye of a user;

at least one target display visible through said eyepiece;

a light source that outputs light that is directed through the eyepiece to the at least one eye of the user;

an interferometer configured to produce optical interference using light reflected from the at least one of eye of the user;

an optical detector disposed so as to detect said optical interference; and

electronics coupled to the at least one target display and said optical detector and configured to provide an output based on optical coherence tomography measurements obtained using said interferometer,

wherein said electronics are further configured to monitor a gaze of the user by tracking detectable structures of the at least one eye using the optical coherence tomography measurements and conduct a functional test based on the gaze of the user, and

wherein said electronics are further configured to compare data from the functional test to a database to determine patterns of deviation.

11. The optical coherence tomography instrument of claim 10 , wherein the electronics are further configured to enable the user to self-administer the functional test.

12. The optical coherence tomography instrument of claim 10 , wherein the electronics are further configured to conduct the functional test on two eyes simultaneously.

13. The optical coherence tomography instrument of claim 10 , wherein the electronics are further configured to conduct the functional test on one eye of the user and then on the other eye of the user.

14. The optical coherence tomography instrument of claim 10 , wherein the electronics are configured to automatically detect strabismus based on the optical coherence tomography measurements.

15. The optical coherence tomography instrument of claim 10 , wherein the at least one target display is configured to display fixation targets configured to move to predetermined positions to test extraocular motility.

16. The optical coherence tomography instrument of claim 10 , wherein the at least one target display is configured to display stationary fixation targets to conduct a fixation stability test.

17. The optical coherence tomography instrument of claim 10 , wherein the electronics are further configured to compare data from the functional test to a database to generate a risk assessment.

18. The optical coherence tomography instrument of claim 10 , wherein the optical coherence tomography instrument is configured to output results of the functional test.

19. The optical coherence tomography instrument of claim 10 , wherein said electronics are configured to monitor the gaze of the user by performing iris plane analysis, pupillary analysis, or foveal or fixation verification.

20. An optical coherence tomography instrument comprising:

an eyepiece for receiving at least one eye of a user;

at least one target display visible through said eyepiece;

a light source that outputs light that is directed through the eyepiece to the at least one eye of the user;

an interferometer configured to produce optical interference using light reflected from the at least one eye of the user;

an optical detector disposed so as to detect said optical interference; and

electronics coupled to the at least one target display and said optical detector and configured to provide an output based on optical coherence tomography measurements obtained using said interferometer,

wherein said electronics are further configured to monitor a gaze of the user by tracking detectable structures of the at least one eye using the optical coherence tomography measurements and conduct a functional test based on the gaze of the user, and

wherein said electronics are further configured to compare data from the functional test to a database to generate a risk assessment.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2021
From: WALSH, ALEXANDER C.; UPDIKE, PAUL G.; SADDA, SRINIVAS R.
To: DOHENY EYE INSTITUTE
Reel/Frame 055323/0086 →
Continuity (16)
Continuation 16184772 · Nov 8, 2018
Continuation 15349970 · Nov 11, 2016
Continuation In Part 15249151 · Aug 26, 2016
Continuation 14521392 · Oct 22, 2014
Continuation 14472161 · Aug 28, 2014
Continuation 13717508 · Dec 17, 2012
Continuation 13054481
Continuation 12111894 · Apr 29, 2008
Provisional Application 61222080 · Jun 30, 2009
Provisional Application 61221552 · Jun 29, 2009
Provisional Application 61180837 · May 23, 2009
Provisional Application 61168340 · Apr 10, 2009
Provisional Application 61082175 · Jul 18, 2008
Provisional Application 61082171 · Jul 18, 2008
Provisional Application 61040084 · Mar 27, 2008
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