IP Library Granted Patent US 12,357,773
Granted Patent B2
US 12,357,773 · App. 17/262,612 · Granted Jul 15, 2025

Nebulizer

Inventors: Tuncay Alan (Clayton, AU); Adrian Neild (Clayton, AU); Nguyen Hoai An Le (Clayton, AU); Jason Brenker (Clayton, AU)
Assignee: Monash University
A61M11/005A61M11/001B05B17/0607B05B17/0615B05B17/0669A61M2205/02A61M2205/0244B05B17/06
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Quick Facts
Patent No.
US 12,357,773
App. No.
17/262,612
Granted
Jul 15, 2025
Kind
B2
Abstract

A nebulizer ( 10 ) having a housing which includes a chamber that has an outlet to the chamber for the egress of atomised fluid particles from within the chamber. The nebulizer ( 10 ) further includes a solid substrate ( 11 ) within the chamber of the housing. A linear channel ( 12 ) is formed in the substrate ( 11 ) that has a closed base, opposite side walls and an opening that opens through an upper surface of the substrate ( 11 ). A vibration generator ( 17 ) is attached to the substrate ( 11 ) at a position spaced from the channel ( 12 ) for generating high frequency vibration that transmits through the substrate ( 11 ) to the channel ( 12 ) to atomise fluid within the channel ( 12 ). A feeding facility ( 15 ) is provided for feeding fluid to the channel ( 12 ).

Claims (46)

1. A nebulizer comprising:

a housing,

the housing defining a chamber and having an outlet to the chamber for the egress of atomised fluid particles from within the chamber,

a solid substrate within the chamber of the housing,

a linear channel formed in the substrate that has a closed base, opposite side walls and an opening that opens through an upper surface of the substrate,

a vibration generator attached to the substrate at a position spaced from the linear channel for generating high frequency vibration that transmits through the substrate to the channel to atomise fluid within the linear channel, and

a feeding facility for feeding fluid to the linear channel,

wherein the linear channel has a high aspect ratio which the depth of the channel is greater than the width, the depth of the channel is in the range of 10.5 micrometres when a linear channel has an aspect ratio of 7:1 and a channel opening of 1.5 micrometres and, up to a 300 micrometers when a channel has aspect ratio of 15:1 and a channel opening of 20 micrometres, and

wherein the linear channel extends fully across the substrate and opens through side edges of the substrate.

2. The nebulizer according to claim 1 , wherein the substrate is a rigid substrate, in particular being formed from silicon.

3. The nebulizer according to claim 1 , wherein the surface of the linear channel is treated to render the surface of the linear channel hydrophilic.

4. The nebulizer according to claim 3 , wherein the surface of the linear channel is treated to render the surface of the linear channel hydrophilic by the application of O 2 plasma to the channel surface.

5. The nebulizer according to claim 1 , wherein the nebulizer includes multiple linear channels that are formed in a parallel array or perpendicular to each other, or in a T or L formation for two channels, or in a C or square/rectangular formation for three or four linear channels.

6. The nebulizer according to claim 1 , wherein the vibration generator is a piezoelectric actuator that employs a piezoelectric disc that is actuated or excited electrically.

7. The nebulizer according to claim 6 , wherein the piezoelectric actuator generates actuation vibrations in a frequency range from 500 KHz to 5 MHz or from 5 MHz to 20 MHz.

8. The nebulizer according to claim 1 , wherein the vibration generator is placed on the upper surface of the substrate.

9. The nebulizer according to claim 1 , wherein the vibration generator is placed on a lower or underneath surface of the substrate opposite to the upper surface through which the linear channel opens.

10. The nebulizer according to claim 9 , wherein the vibration generator is placed directly below the closed base of the linear channel.

11. The nebulizer according to claim 1 , wherein both ends of the linear channel terminate within the substrate.

12. The nebulizer according to claim 1 , wherein the feeding facility has a reservoir into which fluid is fed for subsequent passage or travel into the linear channel.

13. The nebulizer according to claim 12 , wherein the reservoir is formed in the substrate.

14. The nebulizer according to claim 1 , wherein the feeding facility includes a feed conduit or tube that facilitates feed of fluid directly into the linear channel.

15. The nebulizer according to claim 1 , wherein the feeding facility includes an external reservoir spaced from the substrate.

16. A nebulizer comprising:

a housing,

the housing defining a chamber and having an outlet to the chamber for the egress of atomised fluid particles from within the chamber,

a solid substrate within the chamber of the housing,

a linear channel formed in the substrate that has a closed base, opposite side walls and an opening that opens through an upper surface of the substrate,

a vibration generator attached to the substrate at a position spaced from the linear channel for generating high frequency vibration that transmits through the substrate to the channel to atomise fluid within the linear channel, and

a feeding facility for feeding fluid to the linear channel,

wherein the linear channel has a high aspect ratio in which the depth of the channel is greater than the width, the depth of the channel is in the range of 10.5 micrometres when a linear channel has an aspect ratio of 7:1 and a channel opening of 1.5 micrometres and, up to a 300 micrometers when a channel has aspect ratio of 15:1 and a channel opening of 20 micrometres, and

wherein one end of the linear channel opens through one side edge of the substrate and an opposite end of the linear channel terminates within the substrate.

17. A nebulizer comprising:

a solid substrate,

a linear channel formed in the substrate that has a closed base, opposite side walls and an opening that opens through an upper surface of the substrate,

a vibration generator attached to the substrate at a position spaced from the linear channel for generating high frequency vibration that transmits through the substrate to the linear channel to atomise fluid within the linear channel, and

a feeding facility for feeding the fluid to the linear channel,

wherein the linear channel has a high aspect ratio in which the depth of the channel is greater than the width, the depth of the channel is in the range of 10.5 micrometres when a linear channel has an aspect ratio of 7:1 and a channel opening of 1.5 micrometres and, up to a 300 micrometre when a channel has aspect ratio of 15:1 and a channel opening of 20 micrometres, and

wherein the linear channel extends fully across the substrate and opens through side edges of the substrate.

18. A nebulizer comprising:

a solid substrate,

a linear channel formed in the substrate that has a closed base, opposite side walls and an opening that opens through an upper surface of the substrate,

a vibration generator attached to the substrate at a position spaced from the linear channel for generating high frequency vibration that transmits through the substrate to the linear channel to atomise fluid within the linear channel, and

a feeding facility for feeding the fluid to the linear channel,

wherein the linear channel has a high aspect ratio in which the depth of the channel is greater than the width, the depth of the channel is in the range of 10.5 micrometres when a linear channel has an aspect ratio of 7:1 and a channel opening of 1.5 micrometres and, up to a 300 micrometre when a channel has aspect ratio of 15:1 and a channel opening of 20 micrometres, and

wherein one end of the linear channel opens through one side edge of the substrate and an opposite end of the linear channel terminates within the substrate.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 6, 2021
From: ALAN, TUNCAY; NEILD, ADRIAN; HOAI AN LE, NGUYEN; BRENKER, JASON
To: MONASH UNIVERSITY
Reel/Frame 056161/0845 →
Priority Claims (1)
AU 2018902671 · Jul 24, 2018 · national
Continuity (1)
Related Publication 20210268209A1 · Sep 2, 2021
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