IP Library Granted Patent US 12,152,020
Granted Patent B2
US 12,152,020 · App. 17/290,556 · Granted Nov 26, 2024

Pesticidally active azole-amide compounds

Inventors: Amandine Kolleth Krieger (Stein, CH); Andrew Edmunds (Stein, CH); Daniel Emery (Stein, CH); Julien Daniel Henri Gagnepain (Stein, CH); Jürgen Harry Schaetzer (Stein, CH); Thomas Pitterna (Stein, CH); Sebastian Rendler (Stein, CH)
Assignee: SYNGENTA CROP PROTECTION AG
C07D413/14A01N43/653A01N43/82C07D403/04
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Quick Facts
Patent No.
US 12,152,020
App. No.
17/290,556
Granted
Nov 26, 2024
Kind
B2
Abstract

Compounds of formula I wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides.

Claims (20)

1. A compound of the formula I

wherein:

R 1 is hydrogen, C 1 -C 6 alkyl, C 1 -C 6 cyanoalkyl, aminocarbonylC 1 -C 6 alkyl, hydroxycarbonylC 1 -C 6 alkyl, C 1 -C 6 nitroalkyl, trimethylsilaneC 1 -C 6 alkyl, C 1 -C 6 haloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl; C 3 -C 4 cycloalkylC 1 -C 2 alkyl- wherein the C 3 -C 4 cycloalkyl is optionally substituted with 1 or 2 halo atoms; oxetan-3-yl-CH 2 —; or benzyl optionally substituted with halo or C 1 -C 6 haloalkyl;

R 2 is phenyl, pyridine, pyrimidine, pyrazine or pyridazine, wherein the phenyl, pyridine, pyrimidine, pyrazine or pyridazine is optionally substituted with one to three substituents, provided the substituent(s) are not on either carbon adjacent to the carbon C═O is attached, and each substituent is independently selected from: C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, C 1 -C 3 thiohaloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, halogen, NO 2 , SF 5 , CN, CONH 2 , COOH and C(S)NH 2 ;

R 3 is C 1 -C 3 alkyl or C 1 -C 3 haloalkyl;

R 4 is pyridine, pyrimidine, pyrazine or pyridazine, wherein the pyridine, pyrimidine, pyrazine or pyridazine is optionally substituted with one substituent selected from C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, C 1 -C 3 alkoxy, C 3 -C 4 cycloalkyl, halogen or hydroxy;

Z 1 is halogen, CN, NH 2 C(O), amino, (C 1 -C 3 alkyl)amino, di(C 1 -C 3 alkyl)amino, hydroxy, C 3 -C 4 halocycloalkyl, C 3 -C 4 cyanocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, C 1 -C 4 haloalkylsulfanyl, C 1 -C 4 haloalkylsulfinyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylsulfanyl, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 3 alkoxy-C 1 -C 3 alkyl, C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, (C 1 -C 3 alkyl)sulfonylamino, (C 1 -C 3 alkyl)sulfonyl(C 1 -C 3 alkyl)amino, (C 1 -C 3 alkyl)NHC(O), (C 1 -C 3 alkyl) 2 NC(O), (C 1 -C 3 cycloalkyl)NHC(O), (C 1 -C 3 cycloalkyl)(C 1 -C 3 alkyl)NC(O), (C 1 -C 3 alkyl)C(O)(C 1 -C 3 alkyl)N, (C 1 -C 3 alkyl)C(O)NH, (C 1 -C 3 alkyl)C(O), HC(O), diphenylmethanimine, C 1 -C 3 haloalkoxy, phenyl or a 5-membered heteroaromatic ring wherein the phenyl or the 5-membered heteroaromatic ring is optionally substituted with one to three substituents selected from C 1 -C 3 alkyl, C 1 -C 3 haloalkyl, C 1 -C 3 alkoxy, C 3 -C 4 cycloalkyl, halogen, CN or hydroxy; or a stereoisomer, an enantiomer, a tautomer, an N-oxide, or an agrochemically acceptable salt thereof.

2. The compound according to claim 1 , wherein R 3 is methyl.

3. The compound according to claim 1 , wherein R 1 is hydrogen; C 1 -C 6 alkyl optionally substituted with one substituent selected from: CN, CONH 2 , COOH, NO 2 , and —Si(CH 3 ) 3 ; C 1 -C 6 aloalkyl; C 2 -C 6 alkenyl; C 2 -C 6 alkynyl; C 2 -C 6 haloalkynyl; C 3 -C 4 cycloalkyl-C 1 -C 2 alkyl- wherein the C 3 -C 4 cycloalkyl- is optionally substituted with 1 or 2 halo atoms; oxetan-3-yl-CH 2 —; or benzyl optionally substituted with halo or C 1 -C 3 haloalkyl.

4. The compound according to claim 1 , wherein R 2 is one of Y 1 to Y 21

5. The compound according to claim 1 , wherein R 4 is selected from J 1 to J 8

6. The compound according to claim 5 , wherein R 4 is selected from J 1 , J 2 , J 3 , J 4 , J 6 , J 7 , and J 8 .

7. The compound according to claim 4 , wherein R 1 is cyclopropyl-CH 2 —, CH≡CCH 2 —, CH 2 —CHCH 2 —, hydrogen, or methyl; and R 3 is methyl.

8. The compound according to claim 1 , wherein Z 1 is halogen, CN, amino, (C 1 -C 3 alkyl)amino, di(C 1 -C 3 alkyl)amino, hydroxyl, C 3 -C 4 halocycloalkyl, C 3 -C 4 cyanocycloalkyl, C 2 -C 6 alkenyl, C 2 -C 6 haloalkenyl, C 2 -C 6 alkynyl, C 2 -C 6 haloalkynyl, C 1 -C 4 haloalkylsulfanyl, C 1 -C 4 haloalkylsulfinyl, C 1 -C 4 haloalkylsulfonyl, C 1 -C 4 alkylsulfanyl, C 1 -C 4 alkylsulfinyl, C 1 -C 4 alkylsulfonyl, C 1 -C 3 alkoxy-C 1 -C 3 alkyl, (C 1 -C 3 alkyl)sulfonylamino, (C 1 -C 3 alkyl)sulfonyl(C 1 -C 3 alkyl)amino, (C 1 -C 3 alkyl)NHC(O), (C 1 -C 3 alkyl) 2 NC(O), NH 2 C(O), (C 1 -C 3 cycloalkyl)NHC(O), (C 1 -C 3 cycloalkyl)(C 1 -C 3 alkyl)NC(O), (C 1 -C 3 alkyl)C(O)(C 1 -C 3 alkyl)N, (C 1 -C 3 alkyl)C(O)NH, C 1 -C 3 haloalkoxy, (C 1 -C 3 alkyl)C(O), C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, HC(O), or diphenylmethanimine.

9. The compound according to claim 4 , wherein Z 1 is halogen, CN, amino, di(C 1 -C 3 alkyl)amino, hydroxyl, C 3 -C 4 halocycloalkyl, C 3 -C 4 cyanocycloalkyl, (C 1 -C 3 alkyl)NHC(O), (C 1 -C 3 alkyl) 2 NC(O), NH 2 C(O), (C 1 -C 3 cycloalkyl)NHC(O), (C 1 -C 3 cycloalkyl)(C 1 -C 3 alkyl)NC(O), (C 1 -C 3 alkyl)C(O)(C 1 -C 3 alkyl)N, (C 1 -C 3 alkyl)C(O)NH, C 1 -C 3 haloalkoxy, (C 1 -C 3 alkyl)C(O), C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, HC(O), or diphenylmethanimine.

10. A composition comprising a compound as defined in claim 1 , one or more auxiliaries and diluent, and optionally one more other active ingredient.

11. A method of combating and controlling insects, acarines, nematodes or molluscs which comprises applying to a pest, to a locus of a pest, or to a plant susceptible to attack by a pest an insecticidally, acaricidally, nematicidally or molluscicidally effective amount of a compound as defined in claim 1 .

12. A plant propagation material, comprising, or treated with or adhered thereto, a compound as defined in claim 1 .

13. The compound according to 5, wherein Z 1 is halogen, CN, amino, di(C 1 -C 3 alkyl)amino, hydroxyl, C 3 -C 4 halocycloalkyl, C 3 -C 4 cyanocycloalkyl, (C 1 -C 3 alkyl)NHC(O), (C 1 -C 3 alkyl) 2 NC(O), NH 2 C(O), (C 1 -C 3 cycloalkyl)NHC(O), (C 1 -C 3 cycloalkyl)(C 1 -C 3 alkyl)NC(O), (C 1 -C 3 alkyl)C(O)(C 1 -C 3 alkyl)N, (C 1 -C 3 alkyl)C(O)NH, C 1 -C 3 haloalkoxy, (C 1 -C 3 alkyl)C(O), C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, HC(O), or diphenylmethanimine.

14. The compound according to 5, wherein R 1 is cyclopropyl-CH 2 —, CH≡CCH 2 —, CH 2 ═CHCH 2 —, hydrogen, or methyl; and Z 1 is halogen, CN, amino, di(C 1 -C 3 alkyl)amino, hydroxyl, C 3 -C 4 halocycloalkyl, C 3 -C 4 cyanocycloalkyl, (C 1 -C 3 alkyl)NHC(O), (C 1 -C 3 alkyl) 2 NC(O), NH 2 C(O), (C 1 -C 3 cycloalkyl)NHC(O), (C 1 -C 3 cycloalkyl)(C 1 -C 3 alkyl)NC(O), (C 1 -C 3 alkyl)C(O)(C 1 -C 3 alkyl)N, (C 1 -C 3 alkyl)C(O)NH, C 1 -C 3 haloalkoxy, (C 1 -C 3 alkyl)C(O), C 1 -C 3 alkoxy-C 1 -C 3 alkoxy, HC(O), or diphenylmethanimine.

Assignments (2)
MERGER Recorded Jul 31, 2024
From: SYNGENTA PARTICIPATIONS AG
To: SYNGENTA CROP PROTECTION AG
Reel/Frame 068139/0538 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 11, 2021
From: KOLLETH KRIEGER, AMANDINE; EDMUNDS, ANDREW; EMERY, DANIEL; GAGNEPAIN, JULIEN DANIEL HENRI; SCHAETZER, JÜRGEN HARRY; PITTERNA, THOMAS; RENDLER, SEBASTIAN
To: SYNGENTA PARTICIPATIONS AG
Reel/Frame 058080/0485 →
Priority Claims (2)
EP 18204422 · Nov 5, 2018 · regional
EP 19156711 · Feb 12, 2019 · regional
Continuity (1)
Related Publication 20210403462A1 · Dec 30, 2021