Vaccine for protection against
The present invention pertains to a vaccine comprising an IgM protease antigen of Streptococcus suis , for use in a method for protecting a pig against Streptococcus suis , characterised in that the IgM protease antigen is a protein according to SEQ ID NO:1.
1. A vaccine comprising a protein consisting of the amino acid sequence of SEQ ID NO:1 and a pharmaceutically acceptable carrier.
2. The vaccine of claim 1 , wherein the vaccine comprises between 1 and 100 μg of the protein per dose.
3. The vaccine of claim 2 , wherein the vaccine comprises between 1 and 50 μg of the protein per dose.
4. A method for protecting a pig against Streptococcus suis , by administering a vaccine comprising an IgM protease antigen of Streptococcus suis to the pig, wherein the protease antigen is a protein consisting of the amino acid sequence of SEQ ID NO:1.
5. The method of claim 4 , wherein the vaccine is administered twice.
6. The method of claim 4 , wherein the vaccine comprises less than 120 μg of the protein per dose.
7. The method of claim 6 , wherein the vaccine is administered twice.
8. The method of claim 4 , wherein the vaccine comprises a dose of between 10 and 100 μg of the protein.
9. The method of claim 8 , wherein the vaccine is administered twice.
10. The method of claim 4 , wherein the protecting of the pig against Streptococcus suis protects the pig against Streptococcus suis infection.
11. The method of claim 10 , wherein the vaccine is administered twice.
12. The method of claim 10 , wherein the vaccine comprises less than 120 μg of the protein per dose.
13. The method of claim 12 , wherein the vaccine is administered twice.
14. The method of claim 10 , wherein the vaccine comprises a dose of between 10 and 100 μg of the protein.
15. The method of claim 14 , wherein the vaccine is administered twice.