Granted Patent
B2
US 12,311,177 · App. 17/300,305 · Granted May 27, 2025
Method and apparatus for multi modal electrical modulation of pain using composite electromagnetic fields
Inventors:
Ricardo Vallejo (Bloomington, IL); David Leonardo Cedeno (Normal, IL); Nathan A. Torgerson (Andover, MN); Brian Andrew Smith (Minneapolis, MN)
Assignee:
Medtronic SG, LLC
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Abstract
Apparatus and methods for managing pain uses a single composite modulation/stimulation signal with variable characteristics to achieve the same results as separate varying electromagnetic signals, including spinal cord stimulation or peripheral nerve stimulation.
Claims (26)
1. A method for managing pain in a subject comprising:
applying via at least one electrode a first phase segment of a biphasic signal to a nerve area, the first phase segment having a frequency of between 750 Hz and 1400 Hz; and
applying via said at least one electrode a second phase segment of the biphasic signal to said nerve area, the second phase segment having a frequency lower than that of the first phase segment.
2. The method of claim 1 wherein first phase segment has a frequency of about 1200 Hz (burst) and 900 Hz (average).
3. The method of claim 1 wherein the second phase segment has a frequency of about 50 Hz.
4. The method of claim 1 wherein the first phase segment and the second phase segment have any of different respective amplitudes, waveform shapes, widths, phase polarities, and phases relative to each other.
5. The method of claim 1 wherein the biphasic signal is an asymmetric biphasic signal.
6. The method of claim 1 wherein the biphasic signal is a frequency modulated signal.
7. The method of claim 1 wherein the biphasic signal is a phase modulated signal.
8. The method of claim 1 wherein the biphasic signal is a pulse width modulated signal.
9. The method of claim 1 wherein application of biphasic signal is performed without the administration of a pharmacological substance to the subject.
10. The method of claim 1 wherein the pulse width of the first phase segment is between about 170 and 400 microseconds.
11. The method of claim 1 , wherein the biphasic signal is derived from a first electric signal having a current amplitude set to a value corresponding to a percentage of perception threshold of the subject.
12. The method of claim 11 , wherein amplitude of the signals are initially set to zero, with subsequent increase until the patient indicates a perception threshold, with subsequent reduction to a predetermined percentage of perception.
13. The method of claim 12 , wherein the percentage perception is between 20% and 90%.
14. The method of claim 13 , wherein the percentage of perception is between 65% and 75%.
15. The method of claim 11 , further comprising generating a program for said biphasic signal as a first pulse on at least one electrode, and further comprising generating an exact or altered copy of said program for use on a separate electrode or group of electrodes.
16. The method of claim 11 , further comprising generating a program for said biphasic signal as a first pulse on at least one electrode, and further comprising separately generating programs for at least one separate electrode or group of electrodes, including independently assessing perception for the patient and adjusting amplitude of the signal up or down therefrom.
17. The method of claim 1 , wherein said nerve area comprises a spinal cord nerve area.
18. The method of claim 1 , wherein said nerve area comprises a peripheral nerve area.
19. The method of claim 1 , wherein said nerve area comprises a cluster of nerves.
20. The method of claim 1 , wherein the first phase segment comprises a priming component.
21. The method of claim 20 , wherein the second phase segment comprises a tonic component.
22. The method of claim 1 , wherein the biphasic signal is derived from:
a first electric signal having a current amplitude set to a value corresponding to a percentage of priming perception threshold (PPT) of the subject; and
a second electric signal having a current amplitude set to a value corresponding to a percentage of tonic perception threshold (TPT).
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 4, 2022
From: VALLEJO, RICARDO; CEDENO, DAVID LEONARDO; TORGERSON, NATHAN A.; SMITH, BRIAN ANDREW
To: MEDTRONIC SG, LLC
Reel/Frame 058889/0762 →
Continuity (2)
Related Publication
20250114603A9
· Apr 10, 2025
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