IP Library Patent Application 17301236
Patent Application
App. No. 17/301,236

ION ACCELERATION COMPLEX FOR THE TREATMENT OF ATRIAL FIBRILLATIONS

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Quick Facts
Patent No.
US None
App. No.
17/301,236
Abstract

A system ( 12 ) is proposed for the acceleration of ions to treat Atrial Fibrillation (AF), arteriovenous malformations (AVMS) and focal epileptic lesions; this system ( 12 ) includes a pulsed ion source ( 1 ), a pre-accelerator ( 3 ) and one or more linear accelerators or linacs ( 5, 6, 7 ) operating at frequencies above 1 GHz with a repetition rate between 1 Hz and 500 Hz. The particle beam coming out of the complex ( 12 ) can vary (i) in intensity, (ii) in deposition depth and (iii) transversally with respect to the central beam direction. The possibility of adjusting in a few milliseconds and in three orthogonal directions, the location of each energy deposition in the body of the patient makes that system of accelerators ( 12 ) perfectly suited to irradiation of a beating heart.

Claims (22)

1 - 11 . (canceled)

12 . A method of using a linear ion accelerator for the treatment of Atrial Fibrillation (AF) in the heart of a patient in need thereof comprising:

producing beam pulses of accelerated ions with an atomic number between 1 (protons) and 10 (neon ions);

delivering a dose of the beam pulses of accelerated ions to the heart using spot scanning and multi-painting,

wherein a three-dimensional feedback system is used to deliver the dose to treat the AF in the heart without unwanted irradiation of tissues that have to be spared.

13 . The method of claim 12 wherein the feedback system is used to compensate for movements of the irradiated heart.

14 . The method of claim 13 further comprising varying two transverse positions and a depth of each spot before delivering each spot to compensate for movements due to the respiration cycle or to the patient's heartbeat.

15 . The method of claim 14 wherein the variation of the depth corresponds to a variation of energy of the accelerated ions.

16 . A method of using a linear ion accelerator for the treatment of an arteriovenous malformation (AVM) in a patient in need thereof comprising:

producing beam pulses of accelerated ions with an atomic number between 1 (protons) and 10 (neon ions);

delivering a dose of the beam pulses of accelerated ions to the AVM using spot scanning and multi-painting,

wherein a three-dimensional feedback system is used to deliver the dose to the AVM without unwanted irradiation of tissues that have to be spared.

17 . The method of claim 16 wherein the feedback system is used to compensate for movements of the irradiated AVM.

18 . The method of claim 17 further comprising varying two transverse positions and a depth of each spot before delivering each spot to compensate for movements of the AVM.

19 . The method of claim 17 wherein the variation of the depth by the three-dimensional feedback system corresponds to a variation of energy of the accelerated ions.

20 . A method of using a linear ion accelerator for the treatment of an epileptic lesion in a patient in need thereof comprising:

producing beam pulses of accelerated ions with an atomic number between 1 (protons) and 10 (neon ions);

delivering a dose of the beam pulses of accelerated ions to the epileptic lesion using spot scanning and multi-painting,

wherein a three-dimensional feedback system is used to deliver the dose to the epileptic lesion without unwanted irradiation of tissues that have to be spared.

21 . The method of claim 20 wherein the feedback system is used to compensate for movements of the irradiated epileptic lesion.

22 . The method of claim 21 further comprising varying two transverse positions and a depth of each spot before delivering each spot to compensate for movements of the epileptic lesion.

23 . The method of claim 22 wherein the variation of the depth by the three-dimensional feedback system corresponds to a variation of energy of the accelerated ions.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 4, 2022
From: FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA
To: ADVANCED ONCOTHERAPY PLC
Reel/Frame 058545/0650 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2021
From: AMALDI, UGO
To: FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA
Reel/Frame 055763/0028 →