IP Library Granted Patent US 12,161,841
Granted Patent B2
US 12,161,841 · App. 17/303,733 · Granted Dec 10, 2024

Insulin delivery methods, systems and devices

Inventors: Bryan Mazlish (Palo Alto, CA); Lane Desborough (Thousand Oaks, CA)
A61M5/1723A61B5/14532A61M5/14248G16H20/17A61B5/4839A61K38/28A61M5/003A61M5/31568A61M2205/35A61M2205/502A61M2205/52A61M2230/201
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Quick Facts
Patent No.
US 12,161,841
App. No.
17/303,733
Granted
Dec 10, 2024
Kind
B2
Abstract

An insulin delivery monitoring system that includes an insulin delivery device and a controller configured to perform or control performance of operations. A method of insulin delivery include determining a correction dose of insulin and triggering an alert.

Claims (43)

1. A medication delivery monitoring system comprising:

a medication delivery device configured to deliver medication to a user; and

a controller comprising:

at least one processor; and

at least one non-transitory computer-readable storage medium storing instructions thereon that, when executed by the at least one processor, cause the controller to:

responsive to receiving data associated with a previous medication delivery action, determine a correction dose; and

compare the correction dose with a threshold medication delivery amount; and

an alert indicator for indicating an alert responsive to the comparison of the correction dose with the threshold delivery amount.

2. The medication delivery monitoring system of claim 1 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose exceeds the threshold medication delivery amount, trigger an alert.

3. The medication delivery monitoring system of claim 1 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose exceeds the threshold medication delivery amount, adjust parameters for a subsequent medication delivery action.

4. The medication delivery monitoring system of claim 1 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose falls short of the threshold medication delivery amount, cause the medication delivery device to deliver the correction dose.

5. The medication delivery monitoring system of claim 1 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose exceeds the threshold medication delivery amount, exit a feedback mode.

6. The medication delivery monitoring system of claim 1 , wherein determining a correction dose comprises determining the correction dose based at least partially on an equation including:

EGV

-

Target

ISF

-

IOB

7. The medication delivery monitoring system of claim 1 further comprising instructions that, when executed by the at least one processor, cause the controller to: determine the correction dose based at least partially on at least one of (1) a variance between an estimated blood glucose level of a user and a target blood glucose level of the user, (2) a medication sensitivity factor of the user, or (3) an amount of medication on board for the user, the medication on board for the user based at least on an amount of medication delivered by the medication delivery device during the medication delivery action.

8. The medication delivery monitoring system of any of claim 7 , further comprising a blood glucose monitoring device, the blood glucose monitoring device configured to detect the blood glucose level of the user and provide the blood glucose level to the controller.

9. The medication delivery monitoring system of claim 1 , wherein the threshold medication delivery amount is based at least partially on an average total amount of daily basal medication delivered to a user or a nominal basal rate for the user.

10. The medication delivery monitoring system of claim 1 , wherein the threshold medication delivery amount is based at least partially on an estimate of an amount of medication that would typically be administered to a user as basal medication over a period of time between 1 hour and 3 hours.

11. The medication delivery monitoring system of claim 1 , wherein the threshold medication delivery amount comprises a static amount of medication.

12. The medication delivery monitoring system of claim 1 , wherein the threshold medication delivery amount comprises an amount of basal medication delivered during a diurnal time period according to a personalized delivery schedule.

13. A medication delivery monitoring system comprising:

a blood glucose monitoring device, the blood glucose monitoring device configured to detect a blood glucose level of a user; and

a controller comprising:

at least one processor; and

at least one non-transitory computer-readable storage medium storing instructions thereon that, when executed by the at least one processor, cause the controller to:

responsive to determining a correction dose based at least partially on a blood glucose level received from the blood glucose monitoring device, compare the correction dose with a threshold medication delivery amount; and

an alert indicator for indicating an alert responsive to the comparison of the correction dose with the threshold delivery amount.

14. The medication delivery monitoring system of claim 13 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose exceeds the threshold medication delivery amount, trigger an alert.

15. The medication delivery monitoring system of claim 13 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose exceeds the threshold medication delivery amount, adjust parameters for a subsequent medication delivery action.

16. The medication delivery monitoring system of claim 13 , further comprising instructions that, when executed by the at least one processor, cause the controller to: responsive to determining that the correction dose falls short of the threshold medication delivery amount, cause a medication delivery device to deliver the correction dose.

17. The medication delivery monitoring system of claim 13 , further comprising instructions that, when executed by the at least one processor, cause the controller to: estimate a future glucose level.

18. A method of medication delivery monitoring, the method comprising:

receiving data associated an amount of medication delivered by a medication delivery device to a user;

determining a correction dose of medication with a controller in communication;

comparing the correction dose with a threshold medication delivery amount with the controller; and

responsive to the correction dose exceeding the threshold medication delivery amount, triggering an alert with the controller.

19. The method of claim 18 , further comprising: responsive to determining that the correction dose falls short of the threshold medication delivery amount, causing the medication delivery device to deliver the correction dose.

20. The method of claim 18 , further comprising: determining the threshold medication delivery amount based at least partially on at least one of an average total amount of daily basal medication delivered to the user or a nominal basal rate for the user.

Assignments (3)
SECURITY AGREEMENT SUPPLEMENT Recorded Sep 7, 2023
From: INSULET CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS COLLATERAL AGENT
Reel/Frame 064840/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 1, 2023
From: BIGFOOT BIOMEDICAL, INC.
To: INSULET CORPORATION
Reel/Frame 062900/0001 →
RELEASE OF SECURITY INTEREST Recorded Feb 17, 2023
From: MADRYN FUND ADMINISTRATION, LLC
To: BIGFOOT BIOMEDICAL, INC.
Reel/Frame 062793/0316 →
Continuity (3)
Continuation 15870703 · Jan 12, 2018
Provisional Application 62563804 · Sep 27, 2017
Related Publication 20210290845A1 · Sep 23, 2021