PURIFICATION AND SEPARATION TECHNIQUES FOR CANNABINOIDS
This disclosure relates to techniques and methods to isolate and purify cannabinoids, such as CBDV, CBD, CBC, THCV, THC, CBN, CBG, CBDA, THCA, or CBGA. Evaporation and sonicating techniques are used to isolate and purify cannabinoids, such as CBDV, CBD, CBC, THCV, THC, CBN, CBG, CBDA, THCA, or CBGA. The resulting compounds find further use within the devices and compositions described herein as well as for preparative and analytical methods.
1 . A method of purifying secondary compounds from plant material, comprising:
adding the plant material to alcohol;
sonicating the alcohol and plant material;
dissolving secondary compounds in the alcohol to create a solution of secondary compounds;
physically separating the plant material from the solution comprising secondary compounds; and
evaporating the alcohol from the solution.
2 . The method of claim 1 , comprising evaporating the alcohol from the solution at a pressure of less than 1 atmosphere.
3 . The method of claim 1 , comprising sonicating the alcohol and plant material at a temperature of between about −80 to 30 degrees Celsius.
4 . The method of claim 3 , comprising sonicating the alcohol and plant material at a temperature of between about −50 to 10 degrees Celsius.
5 . The method of claim 4 , comprising sonicating the alcohol and plant material at a temperature of between about −30 to −10 degrees Celsius.
6 . The method of claim 1 , comprising evaporating the alcohol from the solution at a temperature of between about 20 to 60 degrees Celsius.
7 . The method of claim 1 , wherein the alcohol is chosen from methanol, ethanol, propanol, and butanol.
8 . The method of claim 7 , wherein the alcohol is ethanol.
9 . The method of claim 1 , comprising collecting a precipitated cannabinoid from within an alcoholic solution of secondary compounds.
10 . The method of claim 9 , comprising dissolving the precipitated cannabinoid in an alcohol, creating a second solution, then recrystallizing the precipitated cannabinoid from the second solution.
11 . The method of claim 10 , comprising evaporating alcohol from the second solution.
12 . The method of claim 10 , wherein the alcohol is ethanol.
13 . A product produced by the method of claim 9 .
14 . The product of claim 13 , wherein the said product comprises single crystals of a cannabinoid.
15 . The product of claim 14 , wherein the said single crystals of a cannabinoid are suitable for x-ray diffraction.
16 . A composition comprising the product of claim 13 .
17 . A device comprising the product of claim 13 , attached to a rigid support means.
18 . The device of claim 17 , comprising a rigid transparent vessel;
wherein said product is contained within said rigid transparent vessel; and
wherein said rigid support means is contained within said rigid transparent vessel.
19 . The device of claim 17 , comprising between 0.1 to 1.0 grams of the said product.