IP Library Patent Application 17335772
Patent Application
App. No. 17/335,772

METAL DI-AMINO ACID CHELATES OR METAL TRI-AMINO ACID CHELATES

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Quick Facts
Patent No.
US None
App. No.
17/335,772
Abstract

The present disclosure relates to metal di-amino acid chelates and metal tri-amino acid chelates.

Claims (29)

1 . A composition comprising a magnesium di-amino acid chelate complex, the complex comprising a magnesium di-amino acid chelate and a counterion, wherein there is a 1:1 ratio between the magnesium and the di-amino acid.

2 . The composition of claim 1 , wherein the di-amino acid is selected from the group consisting of di-glycine (G2), di-aspartic acid (D2), di-glutamic acid (E2), di-histidine (H2), di-serine (S2), and di-tyrosine (Y2).

3 . The composition of claim 1 , wherein each amino acid of the di-amino acid is selected from the group consisting of glycine (G), aspartic acid (D), glutamic acid (E), histidine (H), serine (S), and tyrosine (Y).

4 . The composition of claim 1 , wherein the di-amino acid is di-glycine.

5 . The composition of claim 1 , further comprising at least one vitamin or additional mineral.

6 . A composition comprising a zinc di-amino acid chelate complex, the complex comprising a zinc di-amino acid chelate and optionally a counterion, wherein there is a 1:1 or 1:2 ratio between the zinc and the di-amino acid.

7 . The composition of claim 6 , wherein the di-amino acid is selected from the group consisting of di-glycine (G2), di-aspartic acid (D2), di-glutamic acid (E2), di-histidine (H2), di-serine (S2), and di-tyrosine (Y2).

8 . The composition of claim 6 , wherein each amino acid of the di-amino acid is selected from the group consisting of glycine (G), aspartic acid (D), glutamic acid (E), histidine (H), serine (S), and tyrosine (Y).

9 . The composition of claim 6 , wherein the di-amino acid is di-glycine.

10 . The composition of claim 6 , further comprising at least one vitamin or additional mineral.

11 . A composition comprising a calcium di-amino acid chelate complex, the complex comprising a calcium di-amino acid chelate and optionally a counterion, wherein there is a 1:1 or 1:2 ratio between the calcium and the di-amino acid.

12 . The composition of claim 11 , wherein the di-amino acid is selected from the group consisting of di-glycine (G2), di-aspartic acid (D2), di-glutamic acid (E2), di-histidine (H2), di-serine (S2), and di-tyrosine (Y2).

13 . The composition of claim 11 , wherein each amino acid of the di-amino acid is selected from the group consisting of glycine (G), aspartic acid (D), glutamic acid (E), histidine (H), serine (S), and tyrosine (Y).

14 . The composition of claim 11 , wherein the di-amino acid is di-glycine.

15 . The composition of claim 11 , further comprising at least one vitamin or additional mineral.

16 . A pharmaceutical formulation, the formulation comprising the composition of any of claim 1 .

17 . The pharmaceutical formulation of claim 16 , wherein the formulation is suitable for oral administration.

18 . The pharmaceutical formulation of claim 16 , wherein the formulation is suitable for parenteral administration.

19 . A method of supplying a metal to a subject deficient in a metal, the method comprising administering the chelate of claim 1 to the subject.

20 . The method of claim 19 , wherein the metal is selected from the group consisting of magnesium, calcium, zinc, iron, and a mixture thereof.

21 . A method of producing a metal di-amino acid chelate complex, the method comprising

(i) creating an aqueous solution of a di-amino acid, a metal compound, and optionally an organic acid,

(ii) stirring the solution of step (i) while optionally heating up to 90° C. for a minimum of 10 min,

(iii) cooling the solution and precipitating the metal di-amino acid chelate complex.

22 . The method of claim 21 , the method comprising individually heating an aqueous solution of the di-amino acid and an aqueous solution of the metal compound and optionally organic acid before combining them to create the solution of step (i).

23 . A metal di-amino acid chelate complex formed by the method comprising

(i) creating an aqueous solution of a di-amino acid, a metal compound, and optionally an organic acid,

(ii) stirring the solution of step (i) while optionally heating the solution to less than 90° C. for a minimum of 10 min,

(iii) cooling the combination and precipitating the metal di-amino acid chelate complex.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2022
From: DOYLE, ROBERT
To: SYRACUSE UNIVERSITY
Reel/Frame 061964/0955 →
SECURITY INTEREST Recorded Jul 28, 2022
From: BALCHEM CORPORATION
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 060655/0691 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2022
From: GONZALEZ, REN
To: BALCHEM CORPORATION
Reel/Frame 059158/0614 →