Granted Patent B2

US 12,226,568 · App. 17/338,198 · Granted Feb 18, 2025

Inventors: John Crowder Sigmon, Jr. (Winston-Salem, NC); Shaun D. Gittard (Winston-Salem, NC); Christopher A. Carruthers (Winston-Salem, NC); Liam Breen (Ballina, IE); Vihar C. Surti (Winston-Salem, NC)

Assignee: COOK MEDICAL TECHNOLOGIES LLC

A61M13/00A61J1/2037A61J1/2058A61J1/2065A61M2202/0225A61M2202/064A61M2205/583

Abstract

Claims (39)

1. A system suitable for delivering a therapeutic agent to a target site, the system comprising:

a container for holding the therapeutic agent;

a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container;

a catheter in fluid communication with the container and having a lumen sized for delivery of the therapeutic agent to a target site;

a housing configured to securely retain the container; and

a valve assembly having an inlet port and at least first and second outlet ports, wherein pressurized fluid enters through the inlet port, and in a first state the pressurized fluid is directed through the first outlet port to provide insufflation with the absence of delivery of the therapeutic agent, and in a second state the pressurized fluid is directed through the second outlet port and into the container holding the therapeutic agent to provide delivery of the therapeutic agent,

wherein the valve assembly comprises a plunger configured for linear movement, and

wherein the valve assembly is biased to the first state prior to movement of the plunger.

2. The system of claim 1 , wherein the plunger has a generally tubular body, proximal and distal ends, a lumen extending therebetween, and first and second slots extending through a side surface of the plunger and in communication with the lumen of the plunger, wherein the first slot aligns with the inlet port in both the first and second states, and wherein the second slot selectively aligns with only the first outlet port in the first state and aligns with only the second outlet port in the second state.

3. The system of claim 2 , wherein the first slot comprises a greater axial length than the second slot.

4. The system of claim 1 , wherein the valve assembly comprises a third outlet port that is in selective fluid communication with a reservoir for holding an irrigation fluid, wherein in both the first and second states the pressurized fluid is directed through the third outlet port.

5. The system of claim 4 , wherein an irrigation valve is disposed between the third outlet port of the valve assembly and the catheter, wherein the irrigation valve regulates when the irrigation fluid is delivered through an irrigation lumen of the catheter.

6. A system suitable for delivering a therapeutic agent to a target site, the system comprising:

a container for holding the therapeutic agent;

a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container;

a catheter in fluid communication with the container and having a lumen sized for delivery of the therapeutic agent to a target site; and

a reservoir for holding an irrigation fluid,

wherein the system is able to supply pressure for irrigation, insufflation, and therapeutic agent delivery; and

a valve assembly that routes fluid for each of the irrigation, insufflation and therapeutic agent delivery states, wherein the valve assembly comprises a moveable plunger, and wherein the valve assembly is biased to a first state, prior to movement of the plunger, to provide insufflation.

7. The system of claim 6 wherein the system is able to supply pressure for each of irrigation, insufflation, and therapeutic agent delivery from the same pressure source.

8. The system of claim 6 , wherein the valve assembly has an inlet port and at least first and second outlet ports, wherein pressurized fluid enters through the inlet port, and in the first state the pressurized fluid is directed through the first outlet port to provide insufflation with the absence of delivery of the therapeutic agent, and in a second state the pressurized fluid is directed through the second outlet port and into the container holding the therapeutic agent to provide delivery of the therapeutic agent.

9. The system of claim 6 , further comprising a housing configured to securely retain the container, and wherein the reservoir is securely attached to the housing by an irrigation container, and wherein the irrigation fluid is delivered through an irrigation lumen of the catheter.

10. The system of claim 6 , wherein the plunger is configured for linear movement.

11. A system suitable for delivering a therapeutic agent to a target site, the system comprising:

a container for holding the therapeutic agent;

a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container;

a catheter in fluid communication with the container and having a lumen sized for delivery of the therapeutic agent to a target site;

a housing configured to securely retain the container; and

a valve assembly having an inlet port and at least first and second outlet ports, wherein pressurized fluid enters through the inlet port, and in a first state the pressurized fluid is directed through the first outlet port to provide insufflation with the absence of delivery of the therapeutic agent, and in a second state the pressurized fluid is directed through the second outlet port and into the container holding the therapeutic agent to provide delivery of the therapeutic agent,

wherein the valve assembly comprises a plunger having a generally tubular body, proximal and distal ends, a lumen extending therebetween, and first and second slots extending through a side surface of the plunger and in communication with the lumen of the plunger, wherein the first slot aligns with the inlet port in both the first and second states, and wherein the second slot selectively aligns with only the first outlet port in the first state and aligns with only the second outlet port in the second state.

12. The system of claim 11 , wherein the first slot comprises a greater axial length than the second slot.

13. A system suitable for delivering a therapeutic agent to a target site, the system comprising:

a container for holding the therapeutic agent;

a pressure source having pressurized fluid, the pressure source in selective fluid communication with at least a portion of the container;

a catheter in fluid communication with the container and having a lumen sized for delivery of the therapeutic agent to a target site;

a housing configured to securely retain the container; and

a valve assembly having an inlet port and at least first and second outlet ports, wherein pressurized fluid enters through the inlet port, and in a first state the pressurized fluid is directed through the first outlet port to provide insufflation with the absence of delivery of the therapeutic agent, and in a second state the pressurized fluid is directed through the second outlet port and into the container holding the therapeutic agent to provide delivery of the therapeutic agent,

wherein the valve assembly comprises a third outlet port that is in selective fluid communication with a reservoir for holding an irrigation fluid, wherein in both the first and second states the pressurized fluid is directed through the third outlet port.

14. The system of claim 13 , wherein an irrigation valve is disposed between the third outlet port of the valve assembly and the catheter, wherein the irrigation valve regulates when the irrigation fluid is delivered through an irrigation lumen of the catheter.

Assignments (5)

Continuity (2)

References Cited (400)