IP Library › Granted Patent US 12,257,080
Granted Patent B2
US 12,257,080 · App. 17/340,745 · Granted Mar 25, 2025

Systems, apparatuses, and methods for filtering high voltage noise induced by pulsed electric field ablation

Inventors: Raju Viswanathan (Mountain View, CA); William Bowers (Westminster, CO)
Assignee: Boston Scientific Scimed, Inc.
A61B5/7217A61B5/305A61B5/308A61B18/1206A61B2018/00351A61B2018/00577A61B2018/00839A61B2018/1293A61B18/1492A61N1/3718
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Quick Facts
Patent No.
US 12,257,080
App. No.
17/340,745
Granted
Mar 25, 2025
Kind
B2
Abstract

Systems, apparatuses, and methods for electroporation ablation therapy are disclosed, with a protection device for protecting electronic circuitry, devices, and/or other components from induced currents and voltages generated during a cardiac ablation procedure. A system can include an ablation device near cardiac tissue of a heart. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the ablation device and configured to repeatedly deliver the pulse waveform to the ablation device in synchrony with a set of cardiac cycles of the heart. The system can further include a protection device configured to suppress induced current and voltage in an electronic device coupled to the protection device.

Claims (30)

1. A system, comprising:

a set of electrodes disposable near tissue of a subject;

a signal generator configured to generate a voltage pulse waveform, the signal generator coupleable to the set of electrodes and configured to deliver the voltage pulse waveform to the set of electrodes to ablate the tissue, the set of electrodes configured to induce currents in a first electronic device disposed near the tissue in response to receiving the voltage pulse waveform, wherein the currents induced in the first electronic device include common mode currents; and

a protection device coupleable between the first electronic device and a second electronic device, the protection device configured to reduce the currents induced in the first electronic device, the protection device including a common mode high-impedance element to suppress common mode currents and a capacitor across the high-impedance element to short currents above a predetermined frequency, the high impedance element including a plurality of transformers in series between the first device and the capacitor, the capacitor disposed across the high-impedance element.

2. The system of claim 1 , wherein the first electronic device is a pacing device including a set of leads, and the second electronic device is a cardiac stimulator configured to deliver pacing signals to the pacing device.

3. The system of claim 1 , wherein the currents induced in the first electronic device include differential mode currents, and the plurality of transformers configured to reduce the differential mode currents.

4. The system of claim 3 , wherein each transformer of the one or more transformers includes a toroid core, a first winding around a first portion of the toroid core, and a second winding around a second portion of the toroid core.

5. The system of claim 1 , wherein the protection device includes a plurality of capacitors configured to short currents above a predetermined frequency to reduce the currents induced in the first electronic device.

6. The system of claim 1 , wherein the protection device includes one or more diodes configured to shunt high voltages away from the second electronic device.

7. The system of claim 1 , wherein the protection device includes one or more inductors configured to reduce alternating currents induced in the first electronic device.

8. The system of claim 7 , wherein the one or more inductors includes a first inductor coupled to a first lead of the first electronic device and a second inductor coupled to a second lead of the first electronic device, the first and second inductors configured to reduce alternating currents induced in the first and second leads.

9. The system of claim 1 , wherein:

the capacitor includes a first capacitor and a second capacitor each configured to short voltages above a predetermined frequency;

the plurality of transformers includes a first transformer coupled between the first electronic device and the first capacitor and a second transformer coupled between the first capacitor and the second capacitor; and

the protection device further includes a set of diodes arranged in parallel with the second capacitor and coupled to the second electronic device, the set of diodes configured to shunt high voltages away from the second electronic device.

10. The system of claim 9 , wherein the first and second transformers each are common mode transformers configured to reduce common mode currents induced in the first electronic device.

11. The system of claim 9 , wherein one of the first and second transformers is a differential mode transformer configured to reduce differential mode currents induced in the first electronic device, and the other of the first and second transformers is a common mode transformer configured to reduce common mode currents induced in the first electronic device.

12. The system of claim 1 , wherein the protection device includes one or more balun circuits configured to reduce common mode currents induced in the first electronic device over a predetermined frequency range.

13. The system of claim 12 , wherein the one or more balun circuits includes a plurality of balun circuits each configured to reduce common mode currents induced in the first electronic device over a predetermined frequency range of a set of predetermined frequency ranges, each predetermined frequency range of the set of predetermined frequency ranges at least partially overlapping at least one other predetermined frequency range of the set of predetermined frequency ranges.

14. The system of claim 12 , wherein the protection device includes one or more inductors configured to reduce alternating currents induced in the first electronic device, and the one or more balun circuits are coupled between the one or more inductors and the second electronic device.

15. The system of claim 12 , wherein at least one balun circuit of the one or more balun circuits includes an inductor in parallel with a capacitor and a resistor.

16. The system of claim 12 , wherein at least one balun circuit of the one or more balun circuits includes a coaxial cable winding including first and second conductors, the first conductor coupled to a first lead of the first electronic device and the second conductor coupled to a second lead of the first electronic device.

17. The system of claim 12 , wherein the one or more balun circuits includes a plurality of balun circuits connected in series.

18. The system of claim 1 , wherein the protection device is further coupled between the first electronic device and the signal generator.

19. The system of claim 1 , wherein the protection device is integrated into at least one of the signal generator and the second electronic device.

20. An apparatus, comprising:

a protection device coupleable between a first electronic device and a second electronic device, the first electronic device disposable near tissue of a subject such that currents can be induced in the first electronic device by voltage pulse waveforms delivered to a set of electrodes near tissue, the protection device including:

a set of capacitors each configured to short currents above a predetermined frequency to reduce the currents induced in the first electronic device;

a set of serially coupled transformers each configured to reduce common mode currents or differential mode currents of the currents induced in the first electronic device, wherein a transformer of the set of serially coupled transformers is coupled between two parallel capacitors of the set of capacitors; and

a set of diodes configured to shunt high voltages away from the second electronic device.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2022
From: FARAPULSE, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 060802/0286 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2021
From: VISWANATHAN, RAJU
To: FARAPULSE, INC.
Reel/Frame 056459/0303 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2021
From: BOWERS, WILLIAM
To: CINTRON MEDICAL, INC.
Reel/Frame 056459/0375 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2021
From: CINTRON MEDICAL, INC.
To: FARAPULSE, INC.
Reel/Frame 056459/0387 →
Continuity (4)
Continuation 17091289 · Nov 6, 2020
Continuation PCTUS2019030922 · May 6, 2019
Provisional Application 62667887 · May 7, 2018
Related Publication 20210290172A1 · Sep 23, 2021
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