BIOABSORBABLE POLYMERIC COMPOSITION FOR A MEDICAL DEVICE
A crystallized bioabsorbable polymer scaffold comprises a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold is cold-bendable.
1 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold is cold-bendable.
2 . The bioabsorbable polymer scaffold of claim 1 , wherein the scaffold is cold bendable at temperatures in a range of about 10° C. to about 30° C.
3 . The bioabsorbable polymer scaffold of claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone).
4 . The bioabsorbable polymer scaffold of claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone).
5 . The bioabsorbable polymer scaffold of claim 1 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety.
6 . The bioabsorbable polymer scaffold of claim 1 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water.
7 . The bioabsorbable polymer scaffold of claim 1 , wherein the composition includes amorphous and semicrystalline polymer portions.
8 . The bioabsorbable polymer scaffold of claim 7 , wherein a crystallinity and tensile strength of the composition is adjustable by elongation of the semicrystalline portion.
9 . The bioabsorbable polymer scaffold of claim 1 , further comprising at least one radiopaque marker.
10 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold crystallizes in response to orthogonal strain.
11 . The bioabsorbable polymer scaffold of claim 10 , wherein the scaffold includes struts that orient and crystallize in response to orthogonal strain upon deployment.
12 . The bioabsorbable polymer scaffold of claim 10 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone).
13 . The bioabsorbable polymer scaffold of claim 10 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone).
14 . The bioabsorbable polymer scaffold of claim 10 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety.
15 . The bioabsorbable polymer scaffold of claim 10 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water.
16 . The bioabsorbable polymer scaffold of claim 10 , wherein the composition includes amorphous and semicrystalline polymer portions.
17 . The bioabsorbable polymer scaffold of claim 10 , further comprising at least one radiopaque marker.
18 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) wherein a contaminant monomeric residual fraction in the scaffold does not exceed about 0.5%.
19 . The bioabsorbable polymer scaffold of claim 18 , wherein contaminant monomeric residual fraction in the scaffold does not exceed about 0.3%.
20 . The bioabsorbable polymer scaffold of claim 18 , wherein contaminant monomeric residual fraction in the scaffold does not exceed about 0.2%.
21 . The bioabsorbable polymer scaffold of claim 18 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone).
22 . The bioabsorbable polymer scaffold of claim 18 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone).
23 . The bioabsorbable polymer scaffold of claim 18 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety.
24 . The bioabsorbable polymer scaffold of claim 18 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water.
25 . The bioabsorbable polymer scaffold of claim 18 , wherein the composition includes amorphous and semicrystalline polymer portions.
26 . The bioabsorbable polymer scaffold of claim 25 , wherein a crystallinity and tensile strength of the composition is adjustable by elongation of the semicrystalline portion.
27 . The bioabsorbable polymer scaffold of claim 18 , further comprising at least one radiopaque marker.