Transporter systems, assemblies and associated methods for transporting tissue samples
A tissue sample that has been removed from a subject can be properly fixed for evaluation using the disclosed transporter assembly for carrying a tissue sample and method for fixing an unfixed tissue sample. In one embodiment, the disclosed assembly includes a transport container, a fixative in the transport container, and a cooling device that reduces and/or maintains the temperature of the fixative to perform a pre-soaking process at a temperature of less than about 7° C. The pre-soaking process can, for example, be performed during sample transport or during extended periods of storage, such as over a weekend.
1 . A sample transport device comprising:
(a) a thermally insulated main body;
(b) one or more specimen containers;
(c) a cavity disposed within each of the one or more specimen containers;
(d) one or more lids, wherein each of the one or more lids is removably engageable with one of the one or more specimen containers;
(e) one or more cassette clips removably coupled to the one or more lids;
(f) one or more histology cassettes removably coupled to the one or more cassette clips;
(g) one or more data loggers, wherein each data logger of the one or more data loggers includes a temperature sensor;
one or more carrier assemblies, wherein each carrier assembly includes adjacent first and second openings, wherein the first opening is configured to removably hold one specimen container of the one or more specimen containers, and wherein the second opening is configured to removably hold one of data logger of the one or more data loggers, wherein the first and second openings are in thermal communication;
(h) a tray insertable within the thermally insulated main body, wherein the tray comprises a plurality of receptacles, each of the plurality of receptacles configured to removably hold one carrier assembly of the one or more carrier assemblies;
(i) a cover removably engageable with the thermally insulated main body; and
(j) one or more cooling elements in thermal communication with the plurality of receptacles of the tray, wherein the one or more cooling elements are configured to maintain the plurality of receptacles at a temperature ranging from 0° C. to 10° C. for at least 2 hours.
2 . The sample transport device of claim 1 , wherein each cavity is sized to include a predetermined volume of a fixative solution and a tissue sample.
3 . The sample transport device of claim 1 , wherein each cavity is sized to include the histology cassette.
4 . The sample transport device of claim 2 , wherein the fixative solution is a formalin-based fixative solution.
5 . The sample transport device of claim 1 , wherein each specimen container further comprises a radio frequency identification (RFID) tag.
6 . The sample transport device of claim 1 , wherein the one or more cooling elements comprise a phase change material.
7 . The sample transport of claim 1 , further comprising an accelerometer.
8 . The sample transport system of claim 1 , further comprising a temperature sensor coupled to an outer wall of the thermally insulated main body.
9 . The sample transport system of claim 1 , further comprising a fluid sensor.
10 . The sample transport system of claim 1 , further comprising an ambient light sensor.