Systems and methods for intravascular obstruction removal

1. An intraluminal device, comprising:

a flexible shaft; and

an expandable wire mesh structure extending from the flexible shaft, the wire mesh structure including:

a plurality of pairs of continuous braided wires;

a first expandable section, wherein the plurality of pairs of continuous braided wires form a first braiding arrangement pattern in the first expandable section; and

a second expandable section, wherein the plurality of pairs of continuous braided wires form a second braiding arrangement pattern in the second expandable section, and wherein the second braiding arrangement pattern is different from the first braiding arrangement pattern,

wherein interstices in the first expandable section differ in size from interstices in the second expandable section.

2. The intraluminal device of claim 1 , wherein at least a portion of the first expandable section is braided and at least a portion of the second expandable section is non-braided.

3. The intraluminal device of claim 2 , wherein the interstices of the non-braided portion of the second expandable section are larger than the interstices of the braided portion of the first expandable section.

4. The intraluminal device of claim 2 , wherein the first expandable section includes at least two braided sections separated by a non-braided section.

5. The intraluminal device of claim 2 , wherein the second expandable section includes at least two non-braided sections separated by a braided section.

6. The intraluminal device of claim 2 , wherein the second expandable section includes a plurality of non-braided sections, each disposed between two braided sections.

7. The intraluminal device of claim 2 , further including a control wire extending through the flexible shaft and the expandable mesh structure, the expandable mesh structure being configured to enable a force exerted on the control wire to expand the mesh structure.

8. The intraluminal device of claim 1 , wherein the shaft includes multiple strands of continuous wire that are coiled, and wherein the expandable wire mesh structure is formed from the strands.

9. The intraluminal device of claim 1 , wherein the interstices in the second expandable section are at least three times larger than the interstices in the first expandable section.

10. The intraluminal device of claim 1 , wherein the interstices in the second expandable section are at least five times larger than the interstices in the first expandable section.

11. The intraluminal device of claim 1 , wherein the interstices of the second expandable section are larger than the interstices of the first expandable section, and wherein the wire mesh structure has a third expandable section, wherein the plurality of pairs of continuous braided wires form the first wire braiding arrangement pattern in the third expandable section, the first expandable section and the third expandable section being located on opposing proximal and distal ends of the wire mesh structure.

12. The intraluminal device of claim 1 , wherein when expanded, the second expandable section has an outer diameter greater than an outer diameter of the first expandable section.

13. The intraluminal device of claim 12 , wherein the second expandable section includes a plurality of expandable sections, resulting in an expandable structure with at least two peaks and one valley.

14. The intraluminal device of claim 12 , wherein the first expandable section includes a first plurality of expandable sections, and wherein the second expandable section includes a second plurality of expandable sections, resulting in an expandable structure with a plurality of peaks and a plurality of valleys.

15. The intraluminal device of claim 1 , wherein the plurality of pairs of continuous braided wires include wires having differing cross-sectional shapes.

16. The intraluminal device of claim 1 , wherein the plurality of pairs of continuous braided wires include wires of differing material.

17. The intraluminal device of claim 1 , wherein the plurality of pairs of continuous braided wires include at least one wire having a radio-opacity that differs from a radio-opacity of at least one other wire of the plurality of continuous braided wires.

18. The intraluminal device of claim 1 , wherein the interstices in the second expandable section are at least ten times larger than interstices in the first expandable section.

19. The intraluminal device of claim 1 , wherein the interstices in the second expandable section are twenty times larger than interstices in the first expandable section.

20. A method of removing an obstruction from a vessel, the method comprising:

inserting into the vessel an expandable structure that when expanded, has at least one end region having interstices that are at least three times smaller in size than interstices in a central region, the expandable structure including a plurality of pairs of continuous braided wires, the plurality of pairs of continuous braided wires being in a first braiding arrangement pattern in the at least one end region and in a second braiding arrangement pattern in the central region, the first braiding arrangement pattern being different from the second braiding arrangement pattern;

moving the expandable structure so that at least the central region coincides with the obstruction;

expanding the expandable structure to embed at least a portion of the central region within the obstruction; and

withdrawing from the vessel the expandable structure containing the embedded obstruction.